ID   O69697_MYCTU            Unreviewed;       346 AA.
AC   O69697; F2GFV2; I6Y4E1; Q7D4Z3;
DT   01-AUG-1998, integrated into UniProtKB/TrEMBL.
DT   01-AUG-1998, sequence version 1.
DT   27-MAR-2024, entry version 132.
DE   RecName: Full=DNA ligase D polymerase domain-containing protein {ECO:0000259|Pfam:PF21686};
GN   OrderedLocusNames=Rv3730c {ECO:0000313|EMBL:CCP46557.1};
OS   Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv).
OC   Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83332 {ECO:0000313|EMBL:CCP46557.1, ECO:0000313|Proteomes:UP000001584};
RN   [1] {ECO:0000313|EMBL:CCP46557.1, ECO:0000313|Proteomes:UP000001584}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 25618 / H37Rv {ECO:0000313|Proteomes:UP000001584};
RX   PubMed=9634230; DOI=10.1038/31159;
RA   Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C., Harris D.,
RA   Gordon S.V., Eiglmeier K., Gas S., Barry C.E.III., Tekaia F., Badcock K.,
RA   Basham D., Brown D., Chillingworth T., Connor R., Davies R., Devlin K.,
RA   Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K.,
RA   Krogh A., McLean J., Moule S., Murphy L., Oliver K., Osborne J.,
RA   Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton J.,
RA   Squares R., Squares S., Sulston J.E., Taylor K., Whitehead S.,
RA   Barrell B.G.;
RT   "Deciphering the biology of Mycobacterium tuberculosis from the complete
RT   genome sequence.";
RL   Nature 393:537-544(1998).
RN   [2] {ECO:0007829|PubMed:21969609}
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=21969609; DOI=10.1074/mcp.M111.011445;
RA   Kelkar D.S., Kumar D., Kumar P., Balakrishnan L., Muthusamy B., Yadav A.K.,
RA   Shrivastava P., Marimuthu A., Anand S., Sundaram H., Kingsbury R.,
RA   Harsha H.C., Nair B., Prasad T.S., Chauhan D.S., Katoch K., Katoch V.M.,
RA   Kumar P., Chaerkady R., Ramachandran S., Dash D., Pandey A.;
RT   "Proteogenomic analysis of Mycobacterium tuberculosis by high resolution
RT   mass spectrometry.";
RL   Mol. Cell. Proteomics 10:M111.011627-M111.011627(2011).
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DR   EMBL; AL123456; CCP46557.1; -; Genomic_DNA.
DR   RefSeq; NP_218247.1; NC_000962.3.
DR   RefSeq; WP_003899657.1; NZ_NVQJ01000009.1.
DR   AlphaFoldDB; O69697; -.
DR   SMR; O69697; -.
DR   STRING; 83332.Rv3730c; -.
DR   PaxDb; 83332-Rv3730c; -.
DR   DNASU; 885201; -.
DR   GeneID; 885201; -.
DR   KEGG; mtu:Rv3730c; -.
DR   PATRIC; fig|83332.111.peg.4149; -.
DR   TubercuList; Rv3730c; -.
DR   eggNOG; COG3285; Bacteria.
DR   InParanoid; O69697; -.
DR   OrthoDB; 4296267at2; -.
DR   PhylomeDB; O69697; -.
DR   Proteomes; UP000001584; Chromosome.
DR   CDD; cd04865; LigD_Pol_like_2; 1.
DR   Gene3D; 3.90.920.10; DNA primase, PRIM domain; 1.
DR   InterPro; IPR014145; LigD_pol_dom.
DR   NCBIfam; TIGR02778; ligD_pol; 1.
DR   PANTHER; PTHR42705:SF3; -; 1.
DR   PANTHER; PTHR42705; BIFUNCTIONAL NON-HOMOLOGOUS END JOINING PROTEIN LIGD; 1.
DR   Pfam; PF21686; LigD_Prim-Pol; 1.
PE   1: Evidence at protein level;
KW   Reference proteome {ECO:0000313|Proteomes:UP000001584}.
FT   DOMAIN          33..287
FT                   /note="DNA ligase D polymerase"
FT                   /evidence="ECO:0000259|Pfam:PF21686"
FT   REGION          309..346
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   346 AA;  38544 MW;  11E77E93FBCD155B CRC64;
     MAAAAEELDV DGIAVRLTSP DRMYFPKLGS HGTKRRLVEY YFAVAGGPML TALRDRPTHL
     QRFPDGVDGE QIYQKRIPRH RPDYLQTCRV TFPSGRMADA LKVTHPAAIV WAAQMGTITL
     HPWQVRCPDT EHPDELRIDL DPQPGTGFVE ARTVAVDVLR SVLDDLGLVG YPKTSGGRGI
     HVFLRIATDW DFVEVRRAGI ALAREVERRA PDAVTTSWWK EERGARIFID FNQNARDRTM
     ASAYSVRPTP IATVSMPLTW EELAGADPDD YTMTTVPELV KIRDDPWAGM DDVAQSIAPL
     LDLAAADEER GLGDMPYPPN YPKMPGEPKR VQPSRDTDLK GGNTSK
//