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O69582

- COX3_MYCLE

UniProt

O69582 - COX3_MYCLE

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Protein

Probable cytochrome c oxidase subunit 3

Gene
ctaE, ML0882
Organism
Mycobacterium leprae (strain TN)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

GO - Molecular functioni

  1. cytochrome-c oxidase activity Source: UniProtKB-EC

GO - Biological processi

  1. aerobic electron transport chain Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Names & Taxonomyi

Protein namesi
Recommended name:
Probable cytochrome c oxidase subunit 3 (EC:1.9.3.1)
Alternative name(s):
Cytochrome aa3 subunit 3
Cytochrome c oxidase polypeptide III
Gene namesi
Name:ctaE
Ordered Locus Names:ML0882
OrganismiMycobacterium leprae (strain TN)
Taxonomic identifieri272631 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacterium
ProteomesiUP000000806: Chromosome

Organism-specific databases

LepromaiML0882.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei30 – 5021Helical; Reviewed predictionAdd
BLAST
Transmembranei69 – 8921Helical; Reviewed predictionAdd
BLAST
Transmembranei101 – 12121Helical; Reviewed predictionAdd
BLAST
Transmembranei141 – 16121Helical; Reviewed predictionAdd
BLAST
Transmembranei178 – 19821Helical; Reviewed predictionAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 202202Probable cytochrome c oxidase subunit 3PRO_0000183882Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi272631.ML0882.

Structurei

3D structure databases

ProteinModelPortaliO69582.

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG1845.
HOGENOMiHOG000086399.
KOiK02276.
OMAiMEGDRKH.
OrthoDBiEOG6SFPBZ.

Family and domain databases

Gene3Di1.20.120.80. 1 hit.
InterProiIPR024791. Cyt_c/ubiquinol_Oxase_su3.
IPR013833. Cyt_c_oxidase_su3_a-hlx.
IPR000298. Cyt_c_oxidase_su3_dom.
[Graphical view]
PANTHERiPTHR11403. PTHR11403. 1 hit.
PfamiPF00510. COX3. 1 hit.
[Graphical view]
SUPFAMiSSF81452. SSF81452. 1 hit.
PROSITEiPS50253. COX3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O69582-1 [UniParc]FASTAAdd to Basket

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MTSTVGTLGT AITSRVHSLN RPNMVSVGTV VWLSSELMFF AGLFAMYFTA    50
RAQAGGKWPP STELNLYQAV PVTLVLIASS FTCQMGVFSA ERGDVFGLRR 100
WYVITLLMGL FFVLGQGYEY YHLITHGTTI PSSAYGSVFY LATGFHGLHV 150
TGGLIAFIFL LARTTMSKFT PAQATASIVV SYYWHFVDIV WIALFTVIYF 200
IR 202
Length:202
Mass (Da):22,377
Last modified:August 1, 1998 - v1
Checksum:i1BAB52B96C136B69
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL022602 Genomic DNA. Translation: CAA18701.1.
AL583920 Genomic DNA. Translation: CAC31263.1.
PIRiD87019.
RefSeqiNP_301668.1. NC_002677.1.
WP_010907992.1. NC_002677.1.

Genome annotation databases

EnsemblBacteriaiCAC31263; CAC31263; CAC31263.
GeneIDi909884.
KEGGimle:ML0882.
PATRICi18053336. VBIMycLep78757_1613.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL022602 Genomic DNA. Translation: CAA18701.1 .
AL583920 Genomic DNA. Translation: CAC31263.1 .
PIRi D87019.
RefSeqi NP_301668.1. NC_002677.1.
WP_010907992.1. NC_002677.1.

3D structure databases

ProteinModelPortali O69582.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 272631.ML0882.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAC31263 ; CAC31263 ; CAC31263 .
GeneIDi 909884.
KEGGi mle:ML0882.
PATRICi 18053336. VBIMycLep78757_1613.

Organism-specific databases

Lepromai ML0882.

Phylogenomic databases

eggNOGi COG1845.
HOGENOMi HOG000086399.
KOi K02276.
OMAi MEGDRKH.
OrthoDBi EOG6SFPBZ.

Family and domain databases

Gene3Di 1.20.120.80. 1 hit.
InterProi IPR024791. Cyt_c/ubiquinol_Oxase_su3.
IPR013833. Cyt_c_oxidase_su3_a-hlx.
IPR000298. Cyt_c_oxidase_su3_dom.
[Graphical view ]
PANTHERi PTHR11403. PTHR11403. 1 hit.
Pfami PF00510. COX3. 1 hit.
[Graphical view ]
SUPFAMi SSF81452. SSF81452. 1 hit.
PROSITEi PS50253. COX3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: TN.

Entry informationi

Entry nameiCOX3_MYCLE
AccessioniPrimary (citable) accession number: O69582
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 26, 2005
Last sequence update: August 1, 1998
Last modified: September 3, 2014
This is version 89 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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