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O69582 (COX3_MYCLE) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 88. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable cytochrome c oxidase subunit 3

EC=1.9.3.1
Alternative name(s):
Cytochrome aa3 subunit 3
Cytochrome c oxidase polypeptide III
Gene names
Name:ctaE
Ordered Locus Names:ML0882
OrganismMycobacterium leprae (strain TN) [Complete proteome] [HAMAP]
Taxonomic identifier272631 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacterium

Protein attributes

Sequence length202 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

Subcellular location

Cell membrane; Multi-pass membrane protein By similarity.

Sequence similarities

Belongs to the cytochrome c oxidase subunit 3 family.

Ontologies

Keywords
   Cellular componentCell membrane
Membrane
   DomainTransmembrane
Transmembrane helix
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processaerobic electron transport chain

Inferred from electronic annotation. Source: InterPro

   Cellular_componentintegral component of membrane

Inferred from electronic annotation. Source: UniProtKB-KW

plasma membrane

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functioncytochrome-c oxidase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 202202Probable cytochrome c oxidase subunit 3
PRO_0000183882

Regions

Transmembrane30 – 5021Helical; Potential
Transmembrane69 – 8921Helical; Potential
Transmembrane101 – 12121Helical; Potential
Transmembrane141 – 16121Helical; Potential
Transmembrane178 – 19821Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
O69582 [UniParc].

Last modified August 1, 1998. Version 1.
Checksum: 1BAB52B96C136B69

FASTA20222,377
        10         20         30         40         50         60 
MTSTVGTLGT AITSRVHSLN RPNMVSVGTV VWLSSELMFF AGLFAMYFTA RAQAGGKWPP 

        70         80         90        100        110        120 
STELNLYQAV PVTLVLIASS FTCQMGVFSA ERGDVFGLRR WYVITLLMGL FFVLGQGYEY 

       130        140        150        160        170        180 
YHLITHGTTI PSSAYGSVFY LATGFHGLHV TGGLIAFIFL LARTTMSKFT PAQATASIVV 

       190        200 
SYYWHFVDIV WIALFTVIYF IR 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AL022602 Genomic DNA. Translation: CAA18701.1.
AL583920 Genomic DNA. Translation: CAC31263.1.
PIRD87019.
RefSeqNP_301668.1. NC_002677.1.

3D structure databases

ProteinModelPortalO69582.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING272631.ML0882.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAC31263; CAC31263; CAC31263.
GeneID909884.
KEGGmle:ML0882.
PATRIC18053336. VBIMycLep78757_1613.

Organism-specific databases

LepromaML0882.
CMRSearch...

Phylogenomic databases

eggNOGCOG1845.
HOGENOMHOG000086399.
KOK02276.
OMAMEGDRKH.
OrthoDBEOG6SFPBZ.

Family and domain databases

Gene3D1.20.120.80. 1 hit.
InterProIPR024791. Cyt_c/ubiquinol_Oxase_su3.
IPR000298. Cyt_c_oxidase_su3.
IPR013833. Cyt_c_oxidase_su3_a-hlx.
[Graphical view]
PANTHERPTHR11403. PTHR11403. 1 hit.
PfamPF00510. COX3. 1 hit.
[Graphical view]
SUPFAMSSF81452. SSF81452. 1 hit.
PROSITEPS50253. COX3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCOX3_MYCLE
AccessionPrimary (citable) accession number: O69582
Entry history
Integrated into UniProtKB/Swiss-Prot: April 26, 2005
Last sequence update: August 1, 1998
Last modified: May 14, 2014
This is version 88 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families