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O69582

- COX3_MYCLE

UniProt

O69582 - COX3_MYCLE

Protein

Probable cytochrome c oxidase subunit 3

Gene

ctaE

Organism
Mycobacterium leprae (strain TN)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 90 (01 Oct 2014)
      Sequence version 1 (01 Aug 1998)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

    GO - Molecular functioni

    1. cytochrome-c oxidase activity Source: UniProtKB-EC

    GO - Biological processi

    1. aerobic electron transport chain Source: InterPro

    Keywords - Molecular functioni

    Oxidoreductase

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable cytochrome c oxidase subunit 3 (EC:1.9.3.1)
    Alternative name(s):
    Cytochrome aa3 subunit 3
    Cytochrome c oxidase polypeptide III
    Gene namesi
    Name:ctaE
    Ordered Locus Names:ML0882
    OrganismiMycobacterium leprae (strain TN)
    Taxonomic identifieri272631 [NCBI]
    Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacterium
    ProteomesiUP000000806: Chromosome

    Organism-specific databases

    LepromaiML0882.

    Subcellular locationi

    Cell membrane By similarity; Multi-pass membrane protein By similarity

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. plasma membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cell membrane, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 202202Probable cytochrome c oxidase subunit 3PRO_0000183882Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi272631.ML0882.

    Structurei

    3D structure databases

    ProteinModelPortaliO69582.
    ModBaseiSearch...
    MobiDBiSearch...

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei30 – 5021HelicalSequence AnalysisAdd
    BLAST
    Transmembranei69 – 8921HelicalSequence AnalysisAdd
    BLAST
    Transmembranei101 – 12121HelicalSequence AnalysisAdd
    BLAST
    Transmembranei141 – 16121HelicalSequence AnalysisAdd
    BLAST
    Transmembranei178 – 19821HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiCOG1845.
    HOGENOMiHOG000086399.
    KOiK02276.
    OMAiMEGDRKH.
    OrthoDBiEOG6SFPBZ.

    Family and domain databases

    Gene3Di1.20.120.80. 1 hit.
    InterProiIPR024791. Cyt_c/ubiquinol_Oxase_su3.
    IPR013833. Cyt_c_oxidase_su3_a-hlx.
    IPR000298. Cyt_c_oxidase_su3_dom.
    [Graphical view]
    PANTHERiPTHR11403. PTHR11403. 1 hit.
    PfamiPF00510. COX3. 1 hit.
    [Graphical view]
    SUPFAMiSSF81452. SSF81452. 1 hit.
    PROSITEiPS50253. COX3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    O69582-1 [UniParc]FASTAAdd to Basket

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    MTSTVGTLGT AITSRVHSLN RPNMVSVGTV VWLSSELMFF AGLFAMYFTA    50
    RAQAGGKWPP STELNLYQAV PVTLVLIASS FTCQMGVFSA ERGDVFGLRR 100
    WYVITLLMGL FFVLGQGYEY YHLITHGTTI PSSAYGSVFY LATGFHGLHV 150
    TGGLIAFIFL LARTTMSKFT PAQATASIVV SYYWHFVDIV WIALFTVIYF 200
    IR 202
    Length:202
    Mass (Da):22,377
    Last modified:August 1, 1998 - v1
    Checksum:i1BAB52B96C136B69
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL022602 Genomic DNA. Translation: CAA18701.1.
    AL583920 Genomic DNA. Translation: CAC31263.1.
    PIRiD87019.
    RefSeqiNP_301668.1. NC_002677.1.
    WP_010907992.1. NC_002677.1.

    Genome annotation databases

    EnsemblBacteriaiCAC31263; CAC31263; CAC31263.
    GeneIDi909884.
    KEGGimle:ML0882.
    PATRICi18053336. VBIMycLep78757_1613.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL022602 Genomic DNA. Translation: CAA18701.1 .
    AL583920 Genomic DNA. Translation: CAC31263.1 .
    PIRi D87019.
    RefSeqi NP_301668.1. NC_002677.1.
    WP_010907992.1. NC_002677.1.

    3D structure databases

    ProteinModelPortali O69582.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 272631.ML0882.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CAC31263 ; CAC31263 ; CAC31263 .
    GeneIDi 909884.
    KEGGi mle:ML0882.
    PATRICi 18053336. VBIMycLep78757_1613.

    Organism-specific databases

    Lepromai ML0882.

    Phylogenomic databases

    eggNOGi COG1845.
    HOGENOMi HOG000086399.
    KOi K02276.
    OMAi MEGDRKH.
    OrthoDBi EOG6SFPBZ.

    Family and domain databases

    Gene3Di 1.20.120.80. 1 hit.
    InterProi IPR024791. Cyt_c/ubiquinol_Oxase_su3.
    IPR013833. Cyt_c_oxidase_su3_a-hlx.
    IPR000298. Cyt_c_oxidase_su3_dom.
    [Graphical view ]
    PANTHERi PTHR11403. PTHR11403. 1 hit.
    Pfami PF00510. COX3. 1 hit.
    [Graphical view ]
    SUPFAMi SSF81452. SSF81452. 1 hit.
    PROSITEi PS50253. COX3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: TN.

    Entry informationi

    Entry nameiCOX3_MYCLE
    AccessioniPrimary (citable) accession number: O69582
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 26, 2005
    Last sequence update: August 1, 1998
    Last modified: October 1, 2014
    This is version 90 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3