##gff-version 3
O69548	UniProtKB	Chain	1	947	.	.	.	ID=PRO_0000145158;Note=DNA topoisomerase 1	
O69548	UniProtKB	Domain	16	140	.	.	.	Note=Toprim;Ontology_term=ECO:0000255;evidence=ECO:0000255|HAMAP-Rule:MF_00952	
O69548	UniProtKB	Domain	155	614	.	.	.	Note=Topo IA-type catalytic;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU01383	
O69548	UniProtKB	Region	189	194	.	.	.	Note=Interaction with DNA;Ontology_term=ECO:0000255;evidence=ECO:0000255|HAMAP-Rule:MF_00952	
O69548	UniProtKB	Region	733	771	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
O69548	UniProtKB	Region	846	888	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
O69548	UniProtKB	Region	910	947	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
O69548	UniProtKB	Compositional bias	733	752	.	.	.	Note=Basic and acidic residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
O69548	UniProtKB	Compositional bias	917	933	.	.	.	Note=Basic residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
O69548	UniProtKB	Active site	343	343	.	.	.	Note=O-(5'-phospho-DNA)-tyrosine intermediate;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU01383	
O69548	UniProtKB	Binding site	22	22	.	.	.	Ontology_term=ECO:0000255;evidence=ECO:0000255|HAMAP-Rule:MF_00952	
O69548	UniProtKB	Binding site	109	109	.	.	.	Ontology_term=ECO:0000255;evidence=ECO:0000255|HAMAP-Rule:MF_00952	
O69548	UniProtKB	Site	46	46	.	.	.	Note=Interaction with DNA;Ontology_term=ECO:0000255;evidence=ECO:0000255|HAMAP-Rule:MF_00952	
O69548	UniProtKB	Site	165	165	.	.	.	Note=Interaction with DNA;Ontology_term=ECO:0000255;evidence=ECO:0000255|HAMAP-Rule:MF_00952	
O69548	UniProtKB	Site	166	166	.	.	.	Note=Interaction with DNA;Ontology_term=ECO:0000255;evidence=ECO:0000255|HAMAP-Rule:MF_00952	
O69548	UniProtKB	Site	169	169	.	.	.	Note=Interaction with DNA;Ontology_term=ECO:0000255;evidence=ECO:0000255|HAMAP-Rule:MF_00952	
O69548	UniProtKB	Site	174	174	.	.	.	Note=Interaction with DNA;Ontology_term=ECO:0000255;evidence=ECO:0000255|HAMAP-Rule:MF_00952	
O69548	UniProtKB	Site	181	181	.	.	.	Note=Interaction with DNA;Ontology_term=ECO:0000255;evidence=ECO:0000255|HAMAP-Rule:MF_00952	
O69548	UniProtKB	Site	345	345	.	.	.	Note=Interaction with DNA;Ontology_term=ECO:0000255;evidence=ECO:0000255|HAMAP-Rule:MF_00952	
O69548	UniProtKB	Site	545	545	.	.	.	Note=Interaction with DNA;Ontology_term=ECO:0000255;evidence=ECO:0000255|HAMAP-Rule:MF_00952