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Protein

Chaperone protein DnaK

Gene

dnaK

Organism
Lysinibacillus sphaericus (Bacillus sphaericus)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Acts as a chaperone.By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChaperone
Biological processStress response
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Chaperone protein DnaK
Alternative name(s):
HSP70
Heat shock 70 kDa protein
Heat shock protein 70
Gene namesi
Name:dnaK
OrganismiLysinibacillus sphaericus (Bacillus sphaericus)
Taxonomic identifieri1421 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeLysinibacillus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedBy similarity
ChainiPRO_00000784182 – 611Chaperone protein DnaKAdd BLAST610

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei173Phosphothreonine; by autocatalysisBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PRIDEiO69268

Expressioni

Inductioni

By stress conditions e.g. heat shock (By similarity).By similarity

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliO69268
SMRiO69268
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the heat shock protein 70 family.Curated

Phylogenomic databases

eggNOGiENOG4105CFG Bacteria
COG0443 LUCA

Family and domain databases

Gene3Di1.20.1270.10, 1 hit
2.60.34.10, 1 hit
HAMAPiMF_00332 DnaK, 1 hit
InterProiView protein in InterPro
IPR012725 Chaperone_DnaK
IPR018181 Heat_shock_70_CS
IPR029048 HSP70_C_sf
IPR029047 HSP70_peptide-bd_sf
IPR013126 Hsp_70_fam
PANTHERiPTHR19375 PTHR19375, 1 hit
PfamiView protein in Pfam
PF00012 HSP70, 2 hits
PRINTSiPR00301 HEATSHOCK70
SUPFAMiSSF100920 SSF100920, 1 hit
SSF100934 SSF100934, 1 hit
TIGRFAMsiTIGR02350 prok_dnaK, 1 hit
PROSITEiView protein in PROSITE
PS00297 HSP70_1, 1 hit
PS00329 HSP70_2, 1 hit
PS01036 HSP70_3, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

O69268-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSKIIGIDLG TTNSCVSVLE GGEPKVIPNP EGNRTTPSVV AFKNGERQVG
60 70 80 90 100
EVAKRQSVTN PNTIISIKSK MGTAEKVTVE DKDYTPQEVS AMILQYLKGY
110 120 130 140 150
AEDYLGEKVT KAVITVPAYF NDAQRQATKD AGKIAGLEVE RIINEPTAAA
160 170 180 190 200
LRYGLDKQDQ DQKVLVFDLG GGTFDVSILE LGDGVFEVLA TAGDNKLGGD
210 220 230 240 250
DFDDAIIEYL VAEFKKENGI DLSKDKMAMQ RLKDAAEKAK KDLSGVTSTQ
260 270 280 290 300
ISLPFITAGE AGPLHLEISL TRAKFDEITL PLVNRTVGPV RQALSDAGLS
310 320 330 340 350
TSEIDQVILV GGSTRIPAVQ EAVRKETNKE PHRGVNPDEV VAMGAAVQGG
360 370 380 390 400
VLTGDVKDVV LLDVTPLSLG IETMGGVFTK LIDRNTTIPT SKSQVFSTAA
410 420 430 440 450
DNQPAVDIHV LQGERSMAAD NKTLGRFQLA DIPPAPRGVP QIEVTFDIDK
460 470 480 490 500
NGIVSVKAKD LGTNKEQTIV IQSDSGLSEA EIERMVKDAE ANRDADAKRK
510 520 530 540 550
EEADLRNEAD QLVFQVDKTI TDLGEQITED EKKSVEDARD ELKKALEAGE
560 570 580 590 600
LEGIKAAKEK LEGVLQPLVM KVYEQAAAAA QARQGGEADA GAGKKDDGVV
610
DADFEEVKDD K
Length:611
Mass (Da):65,558
Last modified:January 23, 2007 - v3
Checksum:i24FA34E461B8AE54
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y17157 Genomic DNA Translation: CAA76663.1

Similar proteinsi

Entry informationi

Entry nameiDNAK_LYSSH
AccessioniPrimary (citable) accession number: O69268
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: January 23, 2007
Last modified: May 23, 2018
This is version 85 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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