O69259 (O69259_BORPT) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
P.69C protein EMBL CAA09475.1

Submitted name:
Pertactin EMBL CAA06898.2
Submitted name:
Pertactin outer membrane protein EMBL AAK92093.1

Gene names

Name:	prn EMBL CAA06898.2
Synonyms:	prn3 EMBL CAA09475.1, prnA EMBL AAK92093.1

Organism

Bordetella pertussis EMBL CAA06898.2

Taxonomic identifier

520 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Alcaligenaceae › Bordetella

Protein attributes

Sequence length	910 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Predicted

Ontologies

Keywords
Domain	Signal EMBL CAA06898.2
Gene Ontology (GO)
Biological_process	cell adhesion Inferred from electronic annotation. Source: InterPro
Cellular_component	outer membrane Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 34	34	Potential EMBL CAA06898.2
	Chain	35 – 910	876	P.69C protein EMBL CAA09475.1		PRO_5000064544
	Chain	35 – 910	876	Pertactin EMBL CAA06898.2		PRO_5000064401

Sequences

	Sequence		Length	Mass (Da)
	O69259 [UniParc]. Last modified May 1, 2000. Version 2. Checksum: 9035EE1F07A52BC8	FASTA	910	93,487
	10 20 30 40 50 60 MNMSLSRIVK AAPLRRTTLA MALGALGAAP AAHADWNNQS IVKTGERQHG IHIQGSDPGG 70 80 90 100 110 120 VRTASGTTIK VSGRQAQGIL LENPAAELQF RNGSVTSSGQ LSDDGIRRFL GTVTVKAGKL 130 140 150 160 170 180 VADHATLANV GDTWDDDGIA LYVAGEQAQA SIADSTLQGA GGVQIERGAN VTVQRSAIVD 190 200 210 220 230 240 GGLHIGALQS LQPEDLPPSR VVLRDTNVTA VPASGAPAAV SVLGASELTL DGGHITGGRA 250 260 270 280 290 300 AGVAAMQGAV VHLQRATIRR GDAPAGGAVP GGAVPGGFGP GGFGPGGFGP VLDGWYGVDV 310 320 330 340 350 360 SGSSVELAQS IVEAPELGAA IRVGRGARVT VSGGSLSAPH GNVIETGGAR RFAPQAAPLS 370 380 390 400 410 420 ITLQAGAHAQ GKALLYRVLP EPVKLTLTGG ADAQGDIVAT ELPSIPGTSI GPLDVALASQ 430 440 450 460 470 480 ARWTGATRAV DSLSIDNATW VMTDNSNVGA LRLASDGSVD FQQPAEAGRF KVLTVNTLAG 490 500 510 520 530 540 SGLFRMNVFA DLGLSDKLVV MQDASGQHRL WVRNSGSEPA SANTLLLVQT PLGSAATFTL 550 560 570 580 590 600 ANKDGKVDIG TYRYRLAANG NGQWSLVGAK APPAPKPAPQ PGPQPPQPPQ PQPEAPAPQP 610 620 630 640 650 660 PAGRELSAAA NAAVNTGGVG LASTLWYAES NALSKRLGEL RLNPDAGGAW GRGFAQRQQL 670 680 690 700 710 720 DNRAGRRFDQ KVAGFELGAD HAVAVAGGRW HLGGLAGYTR GDRGFTGDGG GHTDSVHVGG 730 740 750 760 770 780 YATYIADSGF YLDATLRASR LENDFKVAGS DGYAVKGKYR THGVGASLEA GRRFTHADGW 790 800 810 820 830 840 FLEPQAELAV FRAGGGAYRA ANGLRVRDEG GSSVLGRLGL EVGKRIELAG GRQVQPYIKA 850 860 870 880 890 900 SVLQEFDGAG TVHTNGIAHR TELRGTRAEL GLGMAAALGR GHSLYASYEY SKGPKLAMPW 910 TFHAGYRYSW

References

[1]	"Polymorphism in the Bordetella pertussis virulence factors P.69/pertactin and pertussis toxin in The Netherlands: temporal trends and evidence for vaccine-driven evolution." Mooi F.R., van Oirschot H., Heuvelman K., van der Heide H.G., Gaastra W., Willems R.J. Infect. Immun. 66:670-675(1998) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: B343 EMBL CAA09475.1.
[2]	"Intranasal murine model of Bordetella pertussis infection: II. Sequence variation and protection induced by a tricomponent acellular vaccine." Boursaux-Eude C., Thiberge S., Carletti G., Guiso N. Vaccine 17:2651-2660(1999) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: 287 EMBL CAA06898.2 and Al1561 EMBL CAA07477.1.
[3]	"Genotypic variation in the Bordetella pertussis virulence factors pertactin and pertussis toxin in historical and recent clinical isolates in the United Kingdom." Fry N.K., Neal S., Harrison T.G., Miller E., Matthews R., George R.C. Infect. Immun. 69:5520-5528(2001) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: 99K45 EMBL AAK92093.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF348485 Genomic DNA. Translation: AAK92093.1. AJ006156 Genomic DNA. Translation: CAA06898.2. AJ007362 Genomic DNA. Translation: CAA07477.1. AJ011093 Genomic DNA. Translation: CAA09475.1.
3D structure databases
HSSP	HSSP built from PDB template 1DAB based on UniProtKB P14283.
ProteinModelPortal	O69259.
SMR	O69259. Positions 35-573.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
Gene3D	2.160.20.20. 1 hit.
InterPro	IPR005546. Auto_transptbeta. IPR006315. OM_autotransptr_brl. IPR012332. P22_tailspike_C-like. IPR011050. Pectin_lyase_fold/virulence. IPR003992. Pertactin. IPR004899. Pertactin_central. IPR003991. Pertactin_virulence_factor. [Graphical view]
Pfam	PF03797. Autotransporter. 1 hit. PF03212. Pertactin. 1 hit. [Graphical view]
PRINTS	PR01482. PERTACTIN. PR01484. PRTACTNFAMLY.
SMART	SM00869. Autotransporter. 1 hit. [Graphical view]
SUPFAM	SSF103515. Auto_transptbeta. 1 hit. SSF51126. Pectin_lyas_like. 1 hit.
TIGRFAMs	TIGR01414. autotrans_barl. 1 hit.
PROSITE	PS51208. AUTOTRANSPORTER. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

O69259_BORPT

Accession

Primary (citable) accession number: O69259

Entry history

Integrated into UniProtKB/TrEMBL:	August 1, 1998
Last sequence update:	May 1, 2000
Last modified:	April 3, 2013
This is version 58 of the entry and version 2 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)