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Reviewed, UniProtKB/Swiss-Prot O69159 (ACPS_BRAJA)

Last modified November 3, 2009. Version 64. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Holo-[acyl-carrier-protein] synthase
      Short name=Holo-ACP synthase
    EC=2.7.8.7
Alternative name(s):
    4'-phosphopantetheinyl transferase acpS
Gene names
Name: acpS
Ordered Locus Names: bll5063
OrganismBradyrhizobium japonicum [Complete proteome] [HAMAP]
Taxonomic identifier375 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBradyrhizobiaceaeBradyrhizobium

Protein attributes

Sequence length139 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

General annotation (Comments)

Function

Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein By similarity.

Catalytic activity

CoA-(4'-phosphopantetheine) + apo-[acyl-carrier-protein] = adenosine 3',5'-bisphosphate + holo-[acyl-carrier-protein]. HAMAP MF_00101

Cofactor

Magnesium By similarity.

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the P-Pant transferase superfamily. AcpS family.

Ontologies

Keywords
   Biological processFatty acid biosynthesis
Lipid synthesis
   Cellular componentCytoplasm
   LigandMagnesium
Metal-binding
   Molecular functionTransferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processfatty acid biosynthetic process

Inferred from electronic annotation. Source: HAMAP

macromolecule biosynthetic process

Inferred from electronic annotation. Source: InterPro

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionholo-[acyl-carrier-protein] synthase activity

Inferred from electronic annotation. Source: HAMAP

magnesium ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 139139Holo-[acyl-carrier-protein] synthase HAMAP MF_00101
PRO_0000175618

Sites

Metal binding81Magnesium By similarity
Metal binding611Magnesium By similarity

Sequences

Sequence LengthMass (Da)Tools
O69159-1 [UniParc].

Last modified August 1, 1998. Version 1.
Checksum: 2FD4A315845FC788

FASTA13915,193
        10         20         30         40         50         60 
MIIGIGSDLI DITRVGKVIE RHGERFLDRI FTAAERAKAE RRAKNEKMVV ATYAKRFAAK 

        70         80         90        100        110        120 
EACSKALGTG IRRGVWWRDM GVVNLPGGRP TMQLTGGALA RLQALTPDGF EARIDVSITD 

       130 
DWPLAQAFVI ISAVPLAKS 

« Hide

References

« Hide 'large scale' references
[1]"A second gene for type I signal peptidase in Bradyrhizobium japonicum, sipF, is located near genes involved in RNA processing and cell division."
Bairl A., Mueller P.
Mol. Gen. Genet. 260:346-356(1998) [PubMed: 9870699] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: USDA 110spc4.
[2]"Complete genomic sequence of nitrogen-fixing symbiotic bacterium Bradyrhizobium japonicum USDA110."
Kaneko T., Nakamura Y., Sato S., Minamisawa K., Uchiumi T., Sasamoto S., Watanabe A., Idesawa K., Iriguchi M., Kawashima K., Kohara M., Matsumoto M., Shimpo S., Tsuruoka H., Wada T., Yamada M., Tabata S.
DNA Res. 9:189-197(2002) [PubMed: 12597275] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: USDA 110.

Cross-references

Sequence databases

AF065159 Genomic DNA. Translation: AAD02937.1.
BA000040 Genomic DNA. Translation: BAC50328.1.
RefSeqNP_771703.1.

3D structure databases

HSSPHSSP built from PDB template 1F7L based on UniProtKB P96618.
ModBaseSearch...

Genome annotation databases

GeneID1051811.
GenomeReviewsGene locus bll5063 in contig BA000040_GR.
KEGGbja:bll5063.
NMPDRfig|224911.1.peg.5063.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMO69159.
OMAMGVVNLP.

Enzyme and pathway databases

BioCycBJAP224911:BLL5063-MON.
BRENDA2.7.8.7. 280.

Family and domain databases

HAMAPMF_00101.
[Tree]
InterProIPR008278. 4-PPantetheinyl_Trfase.
IPR002582. ACPS.
IPR004568. PPantethiene-prot_Trfase.
[Graphical view]
PfamPF01648. ACPS. 1 hit.
[Graphical view]
ProDomPD004282. ACPS. 1 hit.
[Graphical view] [Entries sharing at least one domain]
TIGRFAMsTIGR00516. acpS. 1 hit.
TIGR00556. pantethn_trn. 1 hit.
ProtoNetSearch...

Entry information

Entry nameACPS_BRAJA
AccessionPrimary (citable) accession number: O69159
Entry history
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: August 1, 1998
Last modified: November 3, 2009
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Relevant documents

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents