O69002 (O69002_PSEAI) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Iron-starvation protein PigA EMBL AAC15188.1

Gene names

Name:

pigA EMBL AAC15188.1

Organism

Pseudomonas aeruginosa EMBL AAC15188.1

Taxonomic identifier

287 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Pseudomonas

Protein attributes

Sequence length	198 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

Ontologies

Keywords
Ligand	Heme PDB 1SK7 Iron Metal-binding
Technical term	3D-structure PDB 1SK7
Gene Ontology (GO)
Biological process	heme oxidation Inferred from electronic annotation. Source: InterPro
Molecular function	heme oxygenase (decyclizing) activity Inferred from electronic annotation. Source: InterPro metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Metal binding	26	1	Iron (heme axial ligand); via tele nitrogen PDB 1SK7

Sequences

	Sequence		Length	Mass (Da)
	O69002 [UniParc]. Last modified August 1, 1998. Version 1. Checksum: 4308A9BE04B03B95	FASTA	198	21,954
	10 20 30 40 50 60 MDTLAPESTR QNLRSQRLNL LTNEPHQRLE SLVKSKEPFA SRDNFARFVA AQYLFQHDLE 70 80 90 100 110 120 PLYRNEALAR LFPGLASRAR DDAARADLAD LGHPVPEGDQ SVREADLSLA EALGWLFVSE 130 140 150 160 170 180 GSKLGAAFLF KKAAALELDE NFGARHLAEP EGGRAQGWKS FVAILDGIEL NEEEERLAAK 190 GASDAFNRFG DLLERTFA

References

[1]	"Gene repression by the ferric uptake regulator in Pseudomonas aeruginosa: cycle selection of iron-regulated genes." Ochsner U.A., Vasil M.L. Proc. Natl. Acad. Sci. U.S.A. 93:4409-4414(1996) [PubMed: 8633080] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: PAO1 EMBL AAC15188.1.
[2]	Ochsner U.A., Johnson Z., Vasil A.I., Vasil M.L. Submitted (APR-1998) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: PAO1 EMBL AAC15188.1.
[3]	"Structural basis for novel delta-regioselective heme oxygenation in the opportunistic pathogen Pseudomonas aeruginosa." Friedman J., Lad L., Li H., Wilks A., Poulos T.L. Biochemistry 43:5239-5245(2004) [PubMed: 15122889] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (1.60 ANGSTROMS) IN COMPLEX WITH HEME.
+	Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

AF060193 Genomic DNA. Translation: AAC15188.1.

PIR

A83562.

RefSeq

NP_249363.1. NC_002516.2.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
1SK7	X-ray	1.60	A	1-198	[»]

ProteinModelPortal

O69002.

SMR

O69002. Positions 12-198.

ModBase

Search...

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Genome annotation databases

GeneID

880820.

GenomeReviews

Gene locus PA0672 in contig AE004091_GR.

KEGG

pae:PA0672.

PATRIC

19835616. VBIPseAer58763_0703.

Organism-specific databases

PseudoCAP

PA0672.

Phylogenomic databases

HOGENOM

HBG575983.

OMA

VVAQYLF.

ProtClustDB

CLSK2517257.

Enzyme and pathway databases

BioCyc

PAER208964:PA0672-MONOMER.

Family and domain databases

InterPro

IPR016053. Haem_Oase-like.
IPR016084. Haem_Oase-like_multi-hlx.
[Graphical view]

Gene3D

G3DSA:1.20.910.10. Haem_Oase-like_multi-hlx. 1 hit.

KO

K07215.

Pfam

PF01126. Heme_oxygenase. 1 hit.
[Graphical view]

SUPFAM

SSF48613. Heme_oxygenase. 1 hit.

ProtoNet

Search...

Entry information

Entry name

O69002_PSEAI

Accession

Primary (citable) accession number: O69002
Secondary accession number(s): Q7DCI2

Entry history

Integrated into UniProtKB/TrEMBL:	August 1, 1998
Last sequence update:	August 1, 1998
Last modified:	January 25, 2012
This is version 60 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)