Reviewed,
UniProtKB/Swiss-Prot O68891 (PARC_ENTSA)
Last modified
June 16, 2009.
Version 42.
History...
Clusters with 100%,
90%,
50% identity |
Documents (1) |
Third-party data |
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Names and origin
| Protein names | Recommended name: DNA topoisomerase 4 subunit A EC=5.99.1.- Alternative name(s): Topoisomerase IV subunit A | ||
| Gene names |
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| Organism | Enterobacter sakazakii | ||
| Taxonomic identifier | 28141 [NCBI] | ||
| Taxonomic lineage | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Cronobacter |
Protein attributes
| Sequence length | 110 AA. |
| Sequence status | Fragment. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Inferred from homology. |
General annotation (Comments)
| Function | Topoisomerase IV is essential for chromosome segregation. It has relaxation of supercoiled DNA activity. Performs the decatenation events required during the replication of a circular DNA molecule By similarity. |
| Subunit structure | Composed of two subunits: parC and parE. |
| Subcellular location | Cell membrane; Peripheral membrane protein By similarity. |
| Sequence similarities | Belongs to the topoisomerase gyrA/parC subunit family. |
Ontologies
| Keywords | |
|---|---|
| Cellular component | Cell membrane Membrane |
| Ligand | DNA-binding |
| Molecular function | Isomerase Topoisomerase |
| Gene Ontology (GO) | |
| Biological process | DNA topological change Inferred from electronic annotation. Source: InterPro |
| Cellular component | chromosome Inferred from electronic annotation. Source: InterPro plasma membraneInferred from electronic annotation. Source: UniProtKB-SubCell |
| Molecular function | ATP binding Inferred from electronic annotation. Source: InterPro DNA topoisomerase (ATP-hydrolyzing) activityInferred from electronic annotation. Source: InterPro |
| Complete GO annotation... | |
Sequence annotation (Features)
Sequences
References
| [1] | Pirapatrungsuriya K., Amyes S.G.B., Thomson C.J. Submitted (MAR-1998) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: NCTC 5920. |
Cross-references
Sequence databases | |
|---|---|
| AF056287 Genomic DNA. Translation: AAC13494.1. | |
3D structure databases | |
| HSSP | HSSP built from PDB template 1AB4 based on UniProtKB P09097. |
| SMR | O68891. Positions 6-110. |
| ModBase | Search... |
Family and domain databases | |
| InterPro | IPR002205. Topo_IIA_A/C. IPR013758. Topo_IIA_A/C_ab. [Graphical view] |
| Gene3D | G3DSA:3.90.199.10. Topo_IIA_A/C_ab. 1 hit. |
| Pfam | PF00521. DNA_topoisoIV. 1 hit. [Graphical view] |
| ProDom | PD000742. DNA_topoisoIV. 1 hit. [Graphical view] [Entries sharing at least one domain] |
| SMART | SM00434. TOP4c. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Other Resources | |
| BindingDB | O68891. |
Entry information
| Entry name | PARC_ENTSA | ||||||||
| Accession | Primary (citable) accession number: O68891 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes) | ||||||||

Clusters with


