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Protein
Submitted name:

Brefeldin A esterase

Gene
N/A
Organism
Bacillus subtilis
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sitei202 – 2021Important for catalytic activityCombined sources
Sitei308 – 3081Important for catalytic activityCombined sources
Sitei338 – 3381Important for catalytic activityCombined sources

GO - Molecular functioni

  1. hydrolase activity Source: InterPro
Complete GO annotation...

Protein family/group databases

MEROPSiS09.951.

Names & Taxonomyi

Protein namesi
Submitted name:
Brefeldin A esteraseImported
OrganismiBacillus subtilisImported
Taxonomic identifieri1423 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1JKMX-ray1.85A/B10-370[»]
ProteinModelPortaliO68884.
SMRiO68884. Positions 10-370.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiO68884.

Family & Domainsi

Family and domain databases

Gene3Di3.40.50.1820. 1 hit.
InterProiIPR029058. AB_hydrolase.
IPR013094. AB_hydrolase_3.
[Graphical view]
PfamiPF07859. Abhydrolase_3. 1 hit.
[Graphical view]
SUPFAMiSSF53474. SSF53474. 1 hit.

Sequencei

Sequence statusi: Complete.

O68884-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTVTPERSTY TPPGRLGDES SGPRTDPRFS PAMVEALATF GLDEVAAAPP
60 70 80 90 100
VSASDDLPTV LAAVGASHDG FQAVYDSIAL DLPTDRDDVE TSTETILGVD
110 120 130 140 150
GNEITLHVFR PAGVEGVLPG LVYTHGGGMT ILTTDNRVHR RWCTDLAAAG
160 170 180 190 200
SVVVMVDFRN AWTAEGHHPF PSGVEDCLAA VLWVDEHRES LGLSGVVVQG
210 220 230 240 250
ESGGGNLAIA TTLLAKRRGR LDAIDGVYAS IPYISGGYAW DHERRLTELP
260 270 280 290 300
SLVENDGYFI ENGGMALLVR AYDPTGEHAE DPIAWPYFAS EDELRGLPPF
310 320 330 340 350
VVAVNELDPL RDEGIAFARR LARAGVDVAA RVNIGLVHGA DVIFRHWLPA
360 370
ALESTVRDVA GFAADRARLR RP
Length:372
Mass (Da):39,839
Last modified:August 1, 1998 - v1
Checksum:i088B30BFA596D5DA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF056081 mRNA. Translation: AAC12774.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF056081 mRNA. Translation: AAC12774.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1JKMX-ray1.85A/B10-370[»]
ProteinModelPortaliO68884.
SMRiO68884. Positions 10-370.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

MEROPSiS09.951.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Miscellaneous databases

EvolutionaryTraceiO68884.

Family and domain databases

Gene3Di3.40.50.1820. 1 hit.
InterProiIPR029058. AB_hydrolase.
IPR013094. AB_hydrolase_3.
[Graphical view]
PfamiPF07859. Abhydrolase_3. 1 hit.
[Graphical view]
SUPFAMiSSF53474. SSF53474. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Crystal structure of brefeldin A esterase, a bacterial homolog of the mammalian hormone-sensitive lipase."
    Wei Y., Contreras J.A., Sheffield P., Osterlund T., Derewenda U., Kneusel R.E., Matern U., Holm C., Derewenda Z.S.
    Nat. Struct. Biol. 6:340-345(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiO68884_BACIU
AccessioniPrimary (citable) accession number: O68884
Entry historyi
Integrated into UniProtKB/TrEMBL: August 1, 1998
Last sequence update: August 1, 1998
Last modified: January 7, 2015
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.