ID   O68600_9PROT            Unreviewed;       269 AA.
AC   O68600;
DT   01-AUG-1998, integrated into UniProtKB/TrEMBL.
DT   01-AUG-1998, sequence version 1.
DT   27-MAR-2024, entry version 73.
DE   SubName: Full=4-chlorobenzoyl CoA dehalogenase {ECO:0000313|EMBL:AAC05576.1};
GN   Name=fcbB {ECO:0000313|EMBL:AAC05576.1};
OS   Pseudomonas sp. DJ-12.
OC   Bacteria; Pseudomonadota.
OX   NCBI_TaxID=74138 {ECO:0000313|EMBL:AAC05576.1};
RN   [1] {ECO:0000313|EMBL:AAC05576.1}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=10340479;
RA   Chae J.C., Kim Y., Min K.H., Kim Y.C., Kim C.K.;
RT   "Cloning and sequencing of the fcbB gene encoding 4-chlorobenzoate-coenzyme
RT   A dehalogenase from Pseudomonas sp. DJ-12.";
RL   Mol. Cells 9:225-229(1999).
RN   [2] {ECO:0000313|EMBL:AAC05576.1}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=11111048; DOI=10.1016/S0378-1119(00)00419-4;
RA   Chae J.C., Kim Y., Kim Y.C., Zylstra G.J., Kim C.K.;
RT   "Genetic structure and functional implication of the fcb gene cluster for
RT   hydrolytic dechlorination of 4-chlorobenzoate from Pseudomonas sp. DJ-12.";
RL   Gene 258:109-116(2000).
RN   [3] {ECO:0000313|EMBL:AAC05576.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Gaut B.S., Morton B.R., Clegg M.T., Duvall M.R.;
RL   Submitted (JAN-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the enoyl-CoA hydratase/isomerase family.
CC       {ECO:0000256|ARBA:ARBA00005254, ECO:0000256|RuleBase:RU003707}.
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DR   EMBL; AF051771; AAC05576.1; -; Genomic_DNA.
DR   AlphaFoldDB; O68600; -.
DR   DrugBank; DB01652; 4-hydroxybenzoyl-CoA.
DR   BRENDA; 3.8.1.6; 5085.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   CDD; cd06558; crotonase-like; 1.
DR   Gene3D; 1.10.12.10; Lyase 2-enoyl-coa Hydratase, Chain A, domain 2; 1.
DR   InterPro; IPR029045; ClpP/crotonase-like_dom_sf.
DR   InterPro; IPR018376; Enoyl-CoA_hyd/isom_CS.
DR   InterPro; IPR001753; Enoyl-CoA_hydra/iso.
DR   InterPro; IPR014748; Enoyl-CoA_hydra_C.
DR   PANTHER; PTHR43684; -; 1.
DR   PANTHER; PTHR43684:SF4; ENOYL-COA HYDRATASE_ISOMERASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_1G01890); 1.
DR   Pfam; PF00378; ECH_1; 1.
DR   SUPFAM; SSF52096; ClpP/crotonase; 1.
DR   PROSITE; PS00166; ENOYL_COA_HYDRATASE; 1.
PE   3: Inferred from homology;
SQ   SEQUENCE   269 AA;  29806 MW;  BAEEE873D25C20AE CRC64;
     MYEAIGHRVQ DGVAEITINL PRHRNALSVK AMQEITDALN RAEEDDNVGA VMITGAADAF
     CAGFYLREIP LDNGVAGIRD HFRVAALWWH QMIHKIIRVK RPVLAAVNGV AAGGGLGVLL
     ASDMAICSDN AKFVCAWHSI GIGNDTATSY SLTRAVGMRR AMELMLTNRT LQPSEACDWG
     IVNRVYPQAQ FRDIAWKAAR ELASVPTHLQ VMAKERFHAG WMQPVEECTE FEIQNVISSV
     THPHFMPRLK RFLDGDKADR AQVELPSGF
//