Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Response regulator

Gene

vieA

Organism
Vibrio cholerae
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  • DNA binding Source: UniProtKB-KW
  • phosphorelay response regulator activity Source: TIGR

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulationSAAS annotation

Keywords - Ligandi

DNA-bindingSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Response regulatorImported
Submitted name:
Response regulator VieAImported
Gene namesi
Name:vieAImported
ORF Names:ERS013186_00345Imported, ERS013198_00794Imported, ERS013200_00652Imported, ERS013202_00384Imported, ERS013206_00752Imported, ERS013207_00136Imported
OrganismiVibrio choleraeImported
Taxonomic identifieri666 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeVibrio
Proteomesi
  • UP000043247 Componenti: Unassembled WGS sequence
  • UP000040416 Componenti: Unassembled WGS sequence
  • UP000044503 Componenti: Unassembled WGS sequence
  • UP000043560 Componenti: Unassembled WGS sequence
  • UP000038065 Componenti: Unassembled WGS sequence
  • UP000041770 Componenti: Unassembled WGS sequence

Subcellular locationi

GO - Cellular componenti

  • intracellular Source: GOC
Complete GO annotation...

Interactioni

Protein-protein interaction databases

STRINGi345073.VC0395_A1258.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini2 – 122121Response regulatoryInterPro annotationAdd
BLAST
Domaini135 – 384250EALInterPro annotationAdd
BLAST
Domaini520 – 58465HTH luxR-type DNA-bindingInterPro annotationAdd
BLAST

Sequence similaritiesi

Contains HTH luxR-type DNA-binding domain.SAAS annotation
Contains response regulatory domain.SAAS annotation

Phylogenomic databases

eggNOGiENOG4108ITG. Bacteria.
COG2197. LUCA.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
3.20.20.450. 1 hit.
InterProiIPR011006. CheY-like_superfamily.
IPR001633. EAL_dom.
IPR016032. Sig_transdc_resp-reg_C-effctor.
IPR001789. Sig_transdc_resp-reg_receiver.
IPR000792. Tscrpt_reg_LuxR_C.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF00563. EAL. 1 hit.
PF00196. GerE. 1 hit.
PF00072. Response_reg. 1 hit.
[Graphical view]
PRINTSiPR00038. HTHLUXR.
SMARTiSM00052. EAL. 1 hit.
SM00421. HTH_LUXR. 1 hit.
SM00448. REC. 1 hit.
[Graphical view]
SUPFAMiSSF141868. SSF141868. 1 hit.
SSF46894. SSF46894. 1 hit.
SSF52172. SSF52172. 1 hit.
PROSITEiPS50883. EAL. 1 hit.
PS00622. HTH_LUXR_1. 1 hit.
PS50043. HTH_LUXR_2. 1 hit.
PS50110. RESPONSE_REGULATORY. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O68318-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKIMIVEDDR IQATSLKLKL RQLGLDDVIL AENGFAALEL CNKVGIDLMF
60 70 80 90 100
CDIRMPQMDG ISLLSQLSLQ APKLGVVILS AVEDTILELT HNMCSLAGFA
110 120 130 140 150
YVDRLPKPYE VEDLQRVVEG FQKQTEPETS HKPAITLTCD EIEQAFLHDH
160 170 180 190 200
IFNYYQPQFD FRSGAMVGVE ALVRYEHPTH GMLSPAVFLP LIEQCGLHEK
210 220 230 240 250
LFLTVLEKSV SALASIGADL QLSVNISQRN LQHSICDPIL AICERYGFPA
260 270 280 290 300
SKLTLEMTEH EVYNGTPTSL ANLARLRMYG VGLSIDDFGT GYASLGQLAQ
310 320 330 340 350
LPFTELKIDR SFVHDLATNY KHQQLTNMCL LLAQSLGLHC VVEGVENEET
360 370 380 390 400
WQYLRQLGVD TCQGYYAAKP MPIAQLSELY TKNRRQCLGC QSMDDGWQIL
410 420 430 440 450
LVDNHMLSAT ALQKVLNKEE NVSKVFVAQD IEQTLHKLRD LPINLLVVES
460 470 480 490 500
RFLSTISPAA FHELLEPYYR GALLVLHDGL TAEAQEDEPK AIVVKANTLM
510 520 530 540 550
ETSSRILLQA QQSNVRPQAQ QEELAQLSER ELTVAKMLVE GLTNKEIALQ
560 570 580
LDINQKTVST YKTRIMTKLG IKSAMELVRF VTLK
Length:584
Mass (Da):65,465
Last modified:August 1, 1998 - v1
Checksum:i384052D40169583B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF031552 Genomic DNA. Translation: AAC38449.1.
CWPO01000001 Genomic DNA. Translation: CSB19256.1.
CWPZ01000001 Genomic DNA. Translation: CSB37132.1.
CWQG01000001 Genomic DNA. Translation: CSB53289.1.
CWQA01000003 Genomic DNA. Translation: CSB59011.1.
CWQD01000002 Genomic DNA. Translation: CSB75281.1.
CWQY01000003 Genomic DNA. Translation: CSC14140.1.
PIRiT09113.

Genome annotation databases

EnsemblBacteriaiCRZ44783; CRZ44783; ERS013276_01711.
CRZ49062; CRZ49062; ERS013242_02260.
CRZ49707; CRZ49707; ERS013250_02285.
CRZ66896; CRZ66896; ERS013126_00453.
CRZ77857; CRZ77857; ERS013178_00533.
CRZ84028; CRZ84028; ERS013254_00396.
CRZ85631; CRZ85631; ERS013252_00533.
CRZ94945; CRZ94945; ERS013127_01622.
CSA03587; CSA03587; ERS013253_00603.
CSA04990; CSA04990; ERS013182_01846.
CSA14695; CSA14695; ERS013257_01227.
CSA15550; CSA15550; ERS013177_01634.
CSA18849; CSA18849; ERS013135_01772.
CSA20682; CSA20682; ERS013258_01263.
CSA22402; CSA22402; ERS013132_00824.
CSA22902; CSA22902; ERS013180_02084.
CSA27201; CSA27201; ERS013181_02219.
CSA30111; CSA30111; ERS013124_01871.
CSA38325; CSA38325; ERS013125_02634.
CSA41163; CSA41163; ERS013133_01718.
CSA43984; CSA43984; ERS013130_02165.
CSA44249; CSA44249; ERS013131_02010.
CSA49841; CSA49841; ERS013175_02017.
CSA50207; CSA50207; ERS013174_01920.
CSA53059; CSA53059; ERS013183_02029.
CSA56678; CSA56678; ERS013179_02333.
CSB07590; CSB07590; ERS013184_00127.
CSB13992; CSB13992; ERS013195_00153.
CSB19256; CSB19256; ERS013186_00345.
CSB26421; CSB26421; ERS013194_00527.
CSB29220; CSB29220; ERS016137_03331.
CSB37132; CSB37132; ERS013207_00136.
CSB47948; CSB47948; ERS013189_01901.
CSB48039; CSB48039; ERS013145_00483.
CSB49978; CSB49978; ERS013185_02556.
CSB52838; CSB52838; ERS013204_00146.
CSB53289; CSB53289; ERS013202_00384.
CSB56761; CSB56761; ERS013196_01589.
CSB58906; CSB58906; ERS013191_01930.
CSB59011; CSB59011; ERS013198_00794.
CSB70978; CSB70978; ERS013187_02162.
CSB75130; CSB75130; ERS013210_00349.
CSB75281; CSB75281; ERS013206_00752.
CSB82948; CSB82948; ERS013142_00479.
CSB94554; CSB94554; ERS013209_01168.
CSB98910; CSB98910; ERS013146_01880.
CSC03237; CSC03237; ERS013217_01393.
CSC12460; CSC12460; ERS013213_01273.
CSC14140; CSC14140; ERS013200_00652.
CSC14252; CSC14252; ERS013216_00711.
CSC16141; CSC16141; ERS013218_02583.
CSC16181; CSC16181; ERS013212_01551.
CSC17033; CSC17033; ERS013139_01961.
CSC19786; CSC19786; ERS013143_02029.
CSC23107; CSC23107; ERS013205_02145.
CSC26090; CSC26090; ERS013188_02716.
CSC43245; CSC43245; ERS013219_02097.
CSC47804; CSC47804; ERS013221_01185.
CSC48399; CSC48399; ERS013137_02240.
CSC57019; CSC57019; ERS013141_01905.
CSC73725; CSC73725; ERS013211_02228.
CSC77691; CSC77691; ERS013226_02133.
CSC97828; CSC97828; ERS013224_02193.
CSD03161; CSD03161; ERS013225_02262.
CSD15630; CSD15630; ERS013266_01503.
CSD16760; CSD16760; ERS013273_01324.
CSD20818; CSD20818; ERS013265_02211.
CSD23813; CSD23813; ERS013234_01344.
CSD23917; CSD23917; ERS013240_00437.
CSD24259; CSD24259; ERS013268_01650.
CSD27544; CSD27544; ERS013267_01795.
CSD27976; CSD27976; ERS013241_01655.
CSD29343; CSD29343; ERS013232_01698.
CSD31866; CSD31866; ERS013270_01714.
CSD34770; CSD34770; ERS013235_01509.
CSD35192; CSD35192; ERS013237_01478.
CSD35807; CSD35807; ERS013236_01537.
CSD50715; CSD50715; ERS013233_01606.
CSD73170; CSD73170; ERS013244_01957.
CSD75931; CSD75931; ERS013271_02595.
CSD79434; CSD79434; ERS013251_01660.
CSD84432; CSD84432; ERS013248_01782.
CSD84826; CSD84826; ERS013246_01943.
CSD90142; CSD90142; ERS013247_02270.
CSD95891; CSD95891; ERS013243_02178.
CSD96043; CSD96043; ERS013275_01833.
CSD98913; CSD98913; ERS013274_01888.
CSE00507; CSE00507; ERS013278_01983.
CSE01593; CSE01593; ERS013245_02213.
CSE03442; CSE03442; ERS013249_02304.
CSE17223; CSE17223; ERS013282_02014.
PATRICi20082366. VBIVibCho83274_1579.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF031552 Genomic DNA. Translation: AAC38449.1.
CWPO01000001 Genomic DNA. Translation: CSB19256.1.
CWPZ01000001 Genomic DNA. Translation: CSB37132.1.
CWQG01000001 Genomic DNA. Translation: CSB53289.1.
CWQA01000003 Genomic DNA. Translation: CSB59011.1.
CWQD01000002 Genomic DNA. Translation: CSB75281.1.
CWQY01000003 Genomic DNA. Translation: CSC14140.1.
PIRiT09113.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi345073.VC0395_A1258.

Protocols and materials databases

DNASUi2613783.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCRZ44783; CRZ44783; ERS013276_01711.
CRZ49062; CRZ49062; ERS013242_02260.
CRZ49707; CRZ49707; ERS013250_02285.
CRZ66896; CRZ66896; ERS013126_00453.
CRZ77857; CRZ77857; ERS013178_00533.
CRZ84028; CRZ84028; ERS013254_00396.
CRZ85631; CRZ85631; ERS013252_00533.
CRZ94945; CRZ94945; ERS013127_01622.
CSA03587; CSA03587; ERS013253_00603.
CSA04990; CSA04990; ERS013182_01846.
CSA14695; CSA14695; ERS013257_01227.
CSA15550; CSA15550; ERS013177_01634.
CSA18849; CSA18849; ERS013135_01772.
CSA20682; CSA20682; ERS013258_01263.
CSA22402; CSA22402; ERS013132_00824.
CSA22902; CSA22902; ERS013180_02084.
CSA27201; CSA27201; ERS013181_02219.
CSA30111; CSA30111; ERS013124_01871.
CSA38325; CSA38325; ERS013125_02634.
CSA41163; CSA41163; ERS013133_01718.
CSA43984; CSA43984; ERS013130_02165.
CSA44249; CSA44249; ERS013131_02010.
CSA49841; CSA49841; ERS013175_02017.
CSA50207; CSA50207; ERS013174_01920.
CSA53059; CSA53059; ERS013183_02029.
CSA56678; CSA56678; ERS013179_02333.
CSB07590; CSB07590; ERS013184_00127.
CSB13992; CSB13992; ERS013195_00153.
CSB19256; CSB19256; ERS013186_00345.
CSB26421; CSB26421; ERS013194_00527.
CSB29220; CSB29220; ERS016137_03331.
CSB37132; CSB37132; ERS013207_00136.
CSB47948; CSB47948; ERS013189_01901.
CSB48039; CSB48039; ERS013145_00483.
CSB49978; CSB49978; ERS013185_02556.
CSB52838; CSB52838; ERS013204_00146.
CSB53289; CSB53289; ERS013202_00384.
CSB56761; CSB56761; ERS013196_01589.
CSB58906; CSB58906; ERS013191_01930.
CSB59011; CSB59011; ERS013198_00794.
CSB70978; CSB70978; ERS013187_02162.
CSB75130; CSB75130; ERS013210_00349.
CSB75281; CSB75281; ERS013206_00752.
CSB82948; CSB82948; ERS013142_00479.
CSB94554; CSB94554; ERS013209_01168.
CSB98910; CSB98910; ERS013146_01880.
CSC03237; CSC03237; ERS013217_01393.
CSC12460; CSC12460; ERS013213_01273.
CSC14140; CSC14140; ERS013200_00652.
CSC14252; CSC14252; ERS013216_00711.
CSC16141; CSC16141; ERS013218_02583.
CSC16181; CSC16181; ERS013212_01551.
CSC17033; CSC17033; ERS013139_01961.
CSC19786; CSC19786; ERS013143_02029.
CSC23107; CSC23107; ERS013205_02145.
CSC26090; CSC26090; ERS013188_02716.
CSC43245; CSC43245; ERS013219_02097.
CSC47804; CSC47804; ERS013221_01185.
CSC48399; CSC48399; ERS013137_02240.
CSC57019; CSC57019; ERS013141_01905.
CSC73725; CSC73725; ERS013211_02228.
CSC77691; CSC77691; ERS013226_02133.
CSC97828; CSC97828; ERS013224_02193.
CSD03161; CSD03161; ERS013225_02262.
CSD15630; CSD15630; ERS013266_01503.
CSD16760; CSD16760; ERS013273_01324.
CSD20818; CSD20818; ERS013265_02211.
CSD23813; CSD23813; ERS013234_01344.
CSD23917; CSD23917; ERS013240_00437.
CSD24259; CSD24259; ERS013268_01650.
CSD27544; CSD27544; ERS013267_01795.
CSD27976; CSD27976; ERS013241_01655.
CSD29343; CSD29343; ERS013232_01698.
CSD31866; CSD31866; ERS013270_01714.
CSD34770; CSD34770; ERS013235_01509.
CSD35192; CSD35192; ERS013237_01478.
CSD35807; CSD35807; ERS013236_01537.
CSD50715; CSD50715; ERS013233_01606.
CSD73170; CSD73170; ERS013244_01957.
CSD75931; CSD75931; ERS013271_02595.
CSD79434; CSD79434; ERS013251_01660.
CSD84432; CSD84432; ERS013248_01782.
CSD84826; CSD84826; ERS013246_01943.
CSD90142; CSD90142; ERS013247_02270.
CSD95891; CSD95891; ERS013243_02178.
CSD96043; CSD96043; ERS013275_01833.
CSD98913; CSD98913; ERS013274_01888.
CSE00507; CSE00507; ERS013278_01983.
CSE01593; CSE01593; ERS013245_02213.
CSE03442; CSE03442; ERS013249_02304.
CSE17223; CSE17223; ERS013282_02014.
PATRICi20082366. VBIVibCho83274_1579.

Phylogenomic databases

eggNOGiENOG4108ITG. Bacteria.
COG2197. LUCA.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
3.20.20.450. 1 hit.
InterProiIPR011006. CheY-like_superfamily.
IPR001633. EAL_dom.
IPR016032. Sig_transdc_resp-reg_C-effctor.
IPR001789. Sig_transdc_resp-reg_receiver.
IPR000792. Tscrpt_reg_LuxR_C.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF00563. EAL. 1 hit.
PF00196. GerE. 1 hit.
PF00072. Response_reg. 1 hit.
[Graphical view]
PRINTSiPR00038. HTHLUXR.
SMARTiSM00052. EAL. 1 hit.
SM00421. HTH_LUXR. 1 hit.
SM00448. REC. 1 hit.
[Graphical view]
SUPFAMiSSF141868. SSF141868. 1 hit.
SSF46894. SSF46894. 1 hit.
SSF52172. SSF52172. 1 hit.
PROSITEiPS50883. EAL. 1 hit.
PS00622. HTH_LUXR_1. 1 hit.
PS50043. HTH_LUXR_2. 1 hit.
PS50110. RESPONSE_REGULATORY. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Nucleotide sequence and spatiotemporal expression of the Vibrio cholerae vieSAB genes during infection."
    Lee S.H., Angelichio M.J., Mekalanos J.J., Camilli A.
    J. Bacteriol. 180:2298-2305(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C6709-1Imported.
  2. Informatics Pathogen
    Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: A232Imported, A316Imported, A346Imported, A346(2)Imported, A481Imported, A482Imported and A483Imported.

Entry informationi

Entry nameiO68318_VIBCL
AccessioniPrimary (citable) accession number: O68318
Secondary accession number(s): Q7DCU2
Entry historyi
Integrated into UniProtKB/TrEMBL: August 1, 1998
Last sequence update: August 1, 1998
Last modified: May 11, 2016
This is version 126 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.