Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

O68280

- GLMS_NOSS9

UniProt

O68280 - GLMS_NOSS9

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Glutamine--fructose-6-phosphate aminotransferase [isomerizing]

Gene

glmS

Organism
Nostoc sp. (strain PCC 9229)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.UniRule annotation

Catalytic activityi

L-glutamine + D-fructose 6-phosphate = L-glutamate + D-glucosamine 6-phosphate.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei2 – 21Nucleophile; for GATase activityUniRule annotation
Active sitei622 – 6221For Fru-6P isomerization activityUniRule annotation

GO - Molecular functioni

  1. carbohydrate binding Source: InterPro
  2. glutamine-fructose-6-phosphate transaminase (isomerizing) activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbohydrate biosynthetic process Source: InterPro
  2. glutamine metabolic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Aminotransferase, Transferase

Protein family/group databases

MEROPSiC44.971.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]UniRule annotation (EC:2.6.1.16UniRule annotation)
Alternative name(s):
D-fructose-6-phosphate amidotransferaseUniRule annotation
GFATUniRule annotation
Glucosamine-6-phosphate synthaseUniRule annotation
Hexosephosphate aminotransferaseUniRule annotation
L-glutamine--D-fructose-6-phosphate amidotransferaseUniRule annotation
Gene namesi
Name:glmSUniRule annotation
Synonyms:nodM
OrganismiNostoc sp. (strain PCC 9229)
Taxonomic identifieri70817 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaNostocalesNostocaceaeNostoc

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methioninei1 – 11RemovedUniRule annotation
Chaini2 – 627626Glutamine--fructose-6-phosphate aminotransferase [isomerizing]PRO_0000135362Add
BLAST

Interactioni

Subunit structurei

Homodimer.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliO68280.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini2 – 224223Glutamine amidotransferase type-2UniRule annotationAdd
BLAST
Domaini293 – 442150SIS 1UniRule annotationAdd
BLAST
Domaini476 – 617142SIS 2UniRule annotationAdd
BLAST

Sequence similaritiesi

Contains 1 glutamine amidotransferase type-2 domain.UniRule annotation
Contains 2 SIS domains.UniRule annotation

Keywords - Domaini

Glutamine amidotransferase, Repeat

Family and domain databases

Gene3Di3.60.20.10. 1 hit.
HAMAPiMF_00164. GlmS.
InterProiIPR017932. GATase_2_dom.
IPR005855. GlmS_trans.
IPR029055. Ntn_hydrolases_N.
IPR001347. SIS.
[Graphical view]
PANTHERiPTHR10937:SF0. PTHR10937:SF0. 1 hit.
PfamiPF01380. SIS. 2 hits.
[Graphical view]
SUPFAMiSSF56235. SSF56235. 1 hit.
TIGRFAMsiTIGR01135. glmS. 1 hit.
PROSITEiPS51278. GATASE_TYPE_2. 1 hit.
PS51464. SIS. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

O68280-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MCGIVGYIGT QAATDILLAG LEKLEYRGYD SAGIATVWEG EINCVRAKGK
60 70 80 90 100
LHNLRSKLEL IETPAQIGIG HTRWATHGKP EEYNAHPHVD TAMPVAVQNG
110 120 130 140 150
IIENYRELRE ELKAKGHVFR SETDTEVIPH LIAEILKNFS ASSSSSDFLE
160 170 180 190 200
AVSQAVNRLE GAFALAVVCA DYPDELIVVR QQAPLVIGFG QGEFFCASDT
210 220 230 240 250
PAIVAYTRAV LPLENGEIAR LTPLGIEIYN FAGHRLKKQP RLLNLNPTMV
260 270 280 290 300
VKTGFKHFML KEIHEQPGVV RASLEAYFNN GRGKWRSPIN LRLPENLYTD
310 320 330 340 350
LEQIHIVACG TSWHAALIGK YLIEQLAGIS TQVHYASEYR YAPSPLTSNT
360 370 380 390 400
LIIGVTQSGE TADTLAALAM EKERRQGKEA KYEARLLGIT NRPESSLLSH
410 420 430 440 450
LVPNIISTLA GIEIGVLATK TFTAQLMAFY ALALDLAAHR QTASKETLEK
460 470 480 490 500
IINGLREIPK DIESTLESQE RLTEQLAHEF AETQDFIFLG RGINFPIALE
510 520 530 540 550
GALKLKEISY IHAEGYPAGE MKHGPIALLD AKVPVVAIAV PGSVYEKVIS
560 570 580 590 600
NAQEAKARDS RLIGVTPVKD GEAGEIFNDL LPVSHVEELL SPLLTVVPLQ
610 620
LLAYHIAARR GLDVDQPRNL AKSVTVE
Length:627
Mass (Da):68,770
Last modified:January 23, 2007 - v3
Checksum:i0DCA6B695C177708
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF028734 Genomic DNA. Translation: AAC17973.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF028734 Genomic DNA. Translation: AAC17973.1 .

3D structure databases

ProteinModelPortali O68280.
ModBasei Search...
MobiDBi Search...

Protein family/group databases

MEROPSi C44.971.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Family and domain databases

Gene3Di 3.60.20.10. 1 hit.
HAMAPi MF_00164. GlmS.
InterProi IPR017932. GATase_2_dom.
IPR005855. GlmS_trans.
IPR029055. Ntn_hydrolases_N.
IPR001347. SIS.
[Graphical view ]
PANTHERi PTHR10937:SF0. PTHR10937:SF0. 1 hit.
Pfami PF01380. SIS. 2 hits.
[Graphical view ]
SUPFAMi SSF56235. SSF56235. 1 hit.
TIGRFAMsi TIGR01135. glmS. 1 hit.
PROSITEi PS51278. GATASE_TYPE_2. 1 hit.
PS51464. SIS. 2 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Characterization of a nodM homologous gene in the symbiotic cyanobacterium Nostoc PCC 9229."
    Viterbo A., Matveyev A., Rasmussen U., Bergman B.
    Submitted (OCT-1997) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Entry informationi

Entry nameiGLMS_NOSS9
AccessioniPrimary (citable) accession number: O68280
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: January 23, 2007
Last modified: October 29, 2014
This is version 69 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3