Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Chaperone protein DnaK

Gene

dnaK

Organism
Burkholderia pseudomallei (strain K96243)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Acts as a chaperone.By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Chaperone

Keywords - Biological processi

Stress response

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Chaperone protein DnaK
Alternative name(s):
HSP70
Heat shock 70 kDa protein
Heat shock protein 70
Gene namesi
Name:dnaK
Synonyms:grpF
Ordered Locus Names:BPSL2827
OrganismiBurkholderia pseudomallei (strain K96243)
Taxonomic identifieri272560 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderiapseudomallei group
Proteomesi
  • UP000000605 Componenti: Chromosome 1

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000784371 – 650Chaperone protein DnaKAdd BLAST650

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei200Phosphothreonine; by autocatalysisBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PRIDEiO68191.

Expressioni

Inductioni

By stress conditions e.g. heat shock (By similarity).By similarity

Interactioni

Protein-protein interaction databases

STRINGi272560.BPSL2827.

Structurei

3D structure databases

ProteinModelPortaliO68191.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the heat shock protein 70 family.Curated

Phylogenomic databases

eggNOGiENOG4105CFG. Bacteria.
COG0443. LUCA.
HOGENOMiHOG000228136.
KOiK04043.
OMAiFYSAKRF.

Family and domain databases

Gene3Di1.20.1270.10. 1 hit.
2.60.34.10. 1 hit.
HAMAPiMF_00332. DnaK. 1 hit.
InterProiIPR012725. Chaperone_DnaK.
IPR018181. Heat_shock_70_CS.
IPR029048. HSP70_C.
IPR029047. HSP70_peptide-bd.
IPR013126. Hsp_70_fam.
[Graphical view]
PfamiPF00012. HSP70. 1 hit.
[Graphical view]
PRINTSiPR00301. HEATSHOCK70.
SUPFAMiSSF100920. SSF100920. 1 hit.
SSF100934. SSF100934. 1 hit.
TIGRFAMsiTIGR02350. prok_dnaK. 1 hit.
PROSITEiPS00297. HSP70_1. 1 hit.
PS00329. HSP70_2. 1 hit.
PS01036. HSP70_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O68191-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGKIIGIDLG TTNSCVAIME GNQVKVIENS EGARTTPSII AYMDDNEVLV
60 70 80 90 100
GAPAKRQSVT NPKNTLFAVK RLIGRRFEEK EVQKDIGLMP YAIIKADNGD
110 120 130 140 150
AWVEAHGEKL APPQVSAEVL RKMKKTAEDY LGEPVTEAVI TVPAYFNDSQ
160 170 180 190 200
RQATKDAGRI AGLEVKRIIN EPTAAALAFG LDKAEKGDRK IAVYDLGGGT
210 220 230 240 250
FDVSIIEIAD VDGEMQFEVL STNGDTFLGG EDFDQRIIDY IIGEFKKEQG
260 270 280 290 300
VDLSKDVLAL QRLKEAAEKA KIELSSSQQT EINLPYITAD ASGPKHLNLK
310 320 330 340 350
VTRAKLEALV EDLVERTIEP CRTAIKDAGV KVSDIDDVIL VGGQTRMPKV
360 370 380 390 400
QEKVKEFFGK EPRRDVNPDE AVAVGAAIQG QVLSGDRKDV LLLDVTPLSL
410 420 430 440 450
GIETLGGVMT KMINKNTTIP TKHAQVYSTA DDNQGAVTIK VFQGEREMAA
460 470 480 490 500
GNKLLGEFNL EGIPPAPRGV PQIEVTFDID ANGILHVGAK DKATGKENKI
510 520 530 540 550
TIKANSGLSE AEIEKMVKDA EANAAEDHKL RELAESRNQG DALVHSTKKA
560 570 580 590 600
LTEYGDKLEA GEKEKIEAAL KELEDVLKNA SSDKAAIDAK VEAVATASQK
610 620 630 640 650
LGEKMYADMQ AQQAGAAGAA GAAAEGASAQ GGAQPADDVV DADFKEVKKD
Length:650
Mass (Da):69,702
Last modified:November 23, 2004 - v2
Checksum:iA386275A28E174D5
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti624A → T in AAC15473 (Ref. 1) Curated1
Sequence conflicti635P → T in AAC15473 (Ref. 1) Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF016711 Genomic DNA. Translation: AAC15473.1.
BX571965 Genomic DNA. Translation: CAH36837.1.
RefSeqiWP_004194034.1. NZ_CP009538.1.
YP_109422.1. NC_006350.1.

Genome annotation databases

EnsemblBacteriaiCAH36837; CAH36837; BPSL2827.
GeneIDi3093638.
KEGGibps:BPSL2827.
PATRICi19266059. VBIBurPse99623_3225.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF016711 Genomic DNA. Translation: AAC15473.1.
BX571965 Genomic DNA. Translation: CAH36837.1.
RefSeqiWP_004194034.1. NZ_CP009538.1.
YP_109422.1. NC_006350.1.

3D structure databases

ProteinModelPortaliO68191.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi272560.BPSL2827.

Proteomic databases

PRIDEiO68191.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAH36837; CAH36837; BPSL2827.
GeneIDi3093638.
KEGGibps:BPSL2827.
PATRICi19266059. VBIBurPse99623_3225.

Phylogenomic databases

eggNOGiENOG4105CFG. Bacteria.
COG0443. LUCA.
HOGENOMiHOG000228136.
KOiK04043.
OMAiFYSAKRF.

Family and domain databases

Gene3Di1.20.1270.10. 1 hit.
2.60.34.10. 1 hit.
HAMAPiMF_00332. DnaK. 1 hit.
InterProiIPR012725. Chaperone_DnaK.
IPR018181. Heat_shock_70_CS.
IPR029048. HSP70_C.
IPR029047. HSP70_peptide-bd.
IPR013126. Hsp_70_fam.
[Graphical view]
PfamiPF00012. HSP70. 1 hit.
[Graphical view]
PRINTSiPR00301. HEATSHOCK70.
SUPFAMiSSF100920. SSF100920. 1 hit.
SSF100934. SSF100934. 1 hit.
TIGRFAMsiTIGR02350. prok_dnaK. 1 hit.
PROSITEiPS00297. HSP70_1. 1 hit.
PS00329. HSP70_2. 1 hit.
PS01036. HSP70_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiDNAK_BURPS
AccessioniPrimary (citable) accession number: O68191
Secondary accession number(s): Q63R46
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 27, 2001
Last sequence update: November 23, 2004
Last modified: November 2, 2016
This is version 96 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.