Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

O68014 (BENM_ACIAD) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 92. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
HTH-type transcriptional regulator BenM
Alternative name(s):
Ben and cat operon transcriptional regulator
Gene names
Name:benM
Synonyms:benR
Ordered Locus Names:ACIAD1435
OrganismAcinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1) [Complete proteome] [HAMAP]
Taxonomic identifier62977 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesMoraxellaceaeAcinetobacter

Protein attributes

Sequence length304 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Positive regulator of the ben and cat genes for benzoate degradation. BenM is necessary for ben gene expression but not for expression of the cat genes, which can be regulated by CatM. Binds to the inducers cis,cis-muconate and benzoate.

Sequence similarities

Contains 1 HTH lysR-type DNA-binding domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 304304HTH-type transcriptional regulator BenM
PRO_0000105594

Regions

Domain1 – 5858HTH lysR-type
DNA binding18 – 3720H-T-H motif Potential

Experimental info

Sequence conflict1571T → S in AAC46441. Ref.1

Secondary structure

.................................................. 304
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
O68014 [UniParc].

Last modified August 31, 2004. Version 2.
Checksum: 23E5837E73039122

FASTA30434,532
        10         20         30         40         50         60 
MELRHLRYFV AVVEEQSFTK AADKLCIAQP PLSRQIQNLE EELGIQLLER GSRPVKTTPE 

        70         80         90        100        110        120 
GHFFYQYAIK LLSNVDQMVS MTKRIASVEK TIRIGFVGSL LFGLLPRIIH LYRQAHPNLR 

       130        140        150        160        170        180 
IELYEMGTKA QTEALKEGRI DAGFGRLKIS DPAIKRTLLR NERLMVAVHA SHPLNQMKDK 

       190        200        210        220        230        240 
GVHLNDLIDE KILLYPSSPK PNFSTHVMNI FSDHGLEPTK INEVREVQLA LGLVAAGEGI 

       250        260        270        280        290        300 
SLVPASTQSI QLFNLSYVPL LDPDAITPIY IAVRNMEEST YIYSLYETIR QIYAYEGFTE 


PPNW 

« Hide

References

« Hide 'large scale' references
[1]"Regulation of benzoate degradation in Acinetobacter sp. strain ADP1 by BenM, a LysR-type transcriptional activator."
Collier L.S., Gaines G.L. III, Neidel E.L.
J. Bacteriol. 180:2493-2501(1998) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]"Unique features revealed by the genome sequence of Acinetobacter sp. ADP1, a versatile and naturally transformation competent bacterium."
Barbe V., Vallenet D., Fonknechten N., Kreimeyer A., Oztas S., Labarre L., Cruveiller S., Robert C., Duprat S., Wincker P., Ornston L.N., Weissenbach J., Marliere P., Cohen G.N., Medigue C.
Nucleic Acids Res. 32:5766-5779(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 33305 / BD413 / ADP1.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF009224 Genomic DNA. Translation: AAC46441.1.
CR543861 Genomic DNA. Translation: CAG68299.1.
RefSeqYP_046121.1. NC_005966.1.

3D structure databases

PDBe
RCSB-PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
2F6GX-ray1.91A/B81-304[»]
2F6PX-ray2.00A/B81-304[»]
2F78X-ray2.05A/B81-304[»]
2F7AX-ray1.90A/B81-304[»]
2F8DX-ray2.70A/B81-304[»]
2F97X-ray2.20A81-304[»]
2H99X-ray1.85A/B1-304[»]
2H9BX-ray1.80A/B1-304[»]
3K1MX-ray2.29A/B1-304[»]
3K1NX-ray2.99A/B1-304[»]
3K1PX-ray3.00A/B1-304[»]
3M1EX-ray1.80A1-87[»]
4IHSX-ray3.10A/B/C/D1-87[»]
4IHTX-ray3.00A/B/C/D1-87[»]
ProteinModelPortalO68014.
SMRO68014. Positions 84-304.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING62977.ACIAD1435.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAG68299; CAG68299; ACIAD1435.
GeneID2880312.
KEGGaci:ACIAD1435.
PATRIC20740682. VBIAciSp98416_1293.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0583.
HOGENOMHOG000233514.
OMADTGRFFY.
OrthoDBEOG686NGM.

Enzyme and pathway databases

BioCycASP62977:GJVV-1363-MONOMER.

Family and domain databases

Gene3D1.10.10.10. 1 hit.
InterProIPR005119. LysR_subst-bd.
IPR000847. Tscrpt_reg_HTH_LysR.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamPF00126. HTH_1. 1 hit.
PF03466. LysR_substrate. 1 hit.
[Graphical view]
PRINTSPR00039. HTHLYSR.
PROSITEPS50931. HTH_LYSR. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

EvolutionaryTraceO68014.

Entry information

Entry nameBENM_ACIAD
AccessionPrimary (citable) accession number: O68014
Secondary accession number(s): Q6FCB2
Entry history
Integrated into UniProtKB/Swiss-Prot: June 20, 2001
Last sequence update: August 31, 2004
Last modified: February 19, 2014
This is version 92 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PDB cross-references

Index of Protein Data Bank (PDB) cross-references