O67942 (CH10_AQUAE) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
10 kDa chaperonin

Alternative name(s):
GroES protein
Protein Cpn10

Gene names

Name:	groS
Synonyms:	groES, mopB
Ordered Locus Names:	aq_2199

Organism

Aquifex aeolicus (strain VF5)

Taxonomic identifier

224324 [NCBI]

Taxonomic lineage

Bacteria › Aquificae › Aquificales › Aquificaceae › Aquifex

Protein attributes

Sequence length	122 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. HAMAP MF_00580
Subunit structure	Heptamer of 7 subunits arranged in a ring By similarity.
Subcellular location	Cytoplasm By similarity HAMAP MF_00580.
Sequence similarities	Belongs to the GroES chaperonin family.

Ontologies

Keywords
Cellular component	Cytoplasm
Molecular function	Chaperone
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	protein folding Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 122	122	10 kDa chaperonin HAMAP MF_00580		PRO_0000174687

Sequences

	Sequence		Length	Mass (Da)
	O67942 [UniParc]. Last modified August 1, 1998. Version 1. Checksum: 700D5FBC30C6C080	FASTA	122	13,639
	10 20 30 40 50 60 MKLRPLYDKI VVERLEEKEE KTPSGIIIPD TAKEKPQLGK VVAVGPGKLL DNGELKPLSV 70 80 90 100 110 120 KEGDVVLFNK YAGNEVEIEG KIYLVMSEDE VLAVVEDYSS LIGGEVRWQQ RQLSTTRKQG QN

References

[1]	"The complete genome of the hyperthermophilic bacterium Aquifex aeolicus." Deckert G., Warren P.V., Gaasterland T., Young W.G., Lenox A.L., Graham D.E., Overbeek R., Snead M.A., Keller M., Aujay M., Huber R., Feldman R.A., Short J.M., Olsen G.J., Swanson R.V. Nature 392:353-358(1998) [PubMed: 9537320] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: VF5.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE000657 Genomic DNA. Translation: AAC07898.1.
PIR	B70489.
RefSeq	NP_214511.1. NC_000918.1.
3D structure databases
ProteinModelPortal	O67942.
SMR	O67942. Positions 1-96.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1193992.
GenomeReviews	Gene locus aq_2199 in contig AE000657_GR.
KEGG	aae:aq_2199.
NMPDR	fig|224324.1.peg.1526.
PATRIC	20961224. VBIAquAeo85532_1702.
Phylogenomic databases
HOGENOM	HBG703377.
OMA	YGVKVEK.
PhylomeDB	O67942.
Enzyme and pathway databases
BioCyc	AAEO224324:AQ_2199-MONOMER.
Family and domain databases
HAMAP	MF_00580. CH10. [Tree]
InterPro	IPR020818. Chaperonin_Cpn10. IPR011032. GroES-like. [Graphical view]
Gene3D	G3DSA:2.30.33.40. Chaprnin_Cpn10. 1 hit.
KO	K04078.
PANTHER	PTHR10772. Chaprnin_Cpn10. 1 hit.
Pfam	PF00166. Cpn10. 1 hit. [Graphical view]
PRINTS	PR00297. CHAPERONIN10.
SMART	SM00883. Cpn10. 1 hit. [Graphical view]
SUPFAM	SSF50129. GroES_like. 1 hit.
PROSITE	PS00681. CHAPERONINS_CPN10. False negative. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

CH10_AQUAE

Accession

Primary (citable) accession number: O67942

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 10, 2002
Last sequence update:	August 1, 1998
Last modified:	January 25, 2012
This is version 63 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program