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Protein
Submitted name:

Cytochrome c oxidase subunit I

Gene

coxA1

Organism
Aquifex aeolicus (strain VF5)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotation

Keywords - Biological processi

Electron transport, Respiratory chainUniRule annotation, Transport

Keywords - Ligandi

HemeUniRule annotation, Iron, Metal-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Cytochrome c oxidase subunit IImported
Gene namesi
Name:coxA1Imported
Ordered Locus Names:aq_2191Imported
OrganismiAquifex aeolicus (strain VF5)Imported
Taxonomic identifieri224324 [NCBI]
Taxonomic lineageiBacteriaAquificaeAquificalesAquificaceaeAquifex
Proteomesi
  • UP000000798 Componenti: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei24 – 45HelicalSequence analysisAdd BLAST22
Transmembranei57 – 81HelicalSequence analysisAdd BLAST25
Transmembranei101 – 127HelicalSequence analysisAdd BLAST27
Transmembranei139 – 166HelicalSequence analysisAdd BLAST28
Transmembranei186 – 210HelicalSequence analysisAdd BLAST25
Transmembranei222 – 244HelicalSequence analysisAdd BLAST23
Transmembranei259 – 282HelicalSequence analysisAdd BLAST24
Transmembranei294 – 314HelicalSequence analysisAdd BLAST21
Transmembranei334 – 355HelicalSequence analysisAdd BLAST22
Transmembranei367 – 389HelicalSequence analysisAdd BLAST23
Transmembranei409 – 430HelicalSequence analysisAdd BLAST22

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Interactioni

Protein-protein interaction databases

STRINGi224324.aq_2191.

Structurei

3D structure databases

ProteinModelPortaliO67935.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 470COX1InterPro annotationAdd BLAST470

Sequence similaritiesi

Belongs to the heme-copper respiratory oxidase family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG4105BZ9. Bacteria.
COG0843. LUCA.
HOGENOMiHOG000085274.
InParanoidiO67935.
OMAiMDITTND.
OrthoDBiPOG091H042R.

Family and domain databases

Gene3Di1.20.210.10. 1 hit.
InterProiIPR000883. COX1.
IPR023616. Cyt_c_oxase-like_su1_dom.
IPR023615. Cyt_c_Oxase_su1_BS.
[Graphical view]
PANTHERiPTHR10422. PTHR10422. 1 hit.
PfamiPF00115. COX1. 1 hit.
[Graphical view]
PRINTSiPR01165. CYCOXIDASEI.
SUPFAMiSSF81442. SSF81442. 1 hit.
PROSITEiPS50855. COX1. 1 hit.
PS00077. COX1_CUB. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O67935-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPGMQVVDFK TYNYLLTGHG VGMLFWWAIA AHIGGFGNFL LPLMIGAKDV
60 70 80 90 100
AFPRLNALSW WAFFAANVLF LMTLIPGNHI MTMWTGYPPF SLNNDAGVTA
110 120 130 140 150
LYVFVMHLLG ASSIATAVNF LVTYITMRAP GYTFFKTNLF VHTLIAANVI
160 170 180 190 200
QLVGVPSLAG AVTMLFLDKY LGTNFFNPAK GGDPLIYQNI FWFYSHPVVY
210 220 230 240 250
VQVLPVFGFY SEIIPVFARR PLFGYTSMVF AVWAITAVSF FLWIHHMFVS
260 270 280 290 300
GVPNWTRVLF SYTTLLIAVP TGIKIFNWML TLYRGAIHFR SQMLYALGGV
310 320 330 340 350
FMFLIGGLTG LPLGMVAIDL GVSDSLFVVG HFHYVLGMAI TLGILGAVIH
360 370 380 390 400
WFPLATGKYY PENLGKLSFW LIFAGANIFY FLQMVAGMLG NPRRYPDYPP
410 420 430 440 450
IPEWTTLHVI QTIGALILGV GVVIFTYGII KGLKSGEKAS DNPWKSPSLE
460 470 480
WKVGVPARAH GHGDHPPRVE PDWHPYRYDK EEILK
Length:485
Mass (Da):54,170
Last modified:August 1, 1998 - v1
Checksum:i4F7EEBA1DBEC18A7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000657 Genomic DNA. Translation: AAC07899.1.
PIRiC70488.

Genome annotation databases

EnsemblBacteriaiAAC07899; AAC07899; aq_2191.
PATRICi20961208. VBIAquAeo85532_1694.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000657 Genomic DNA. Translation: AAC07899.1.
PIRiC70488.

3D structure databases

ProteinModelPortaliO67935.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi224324.aq_2191.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC07899; AAC07899; aq_2191.
PATRICi20961208. VBIAquAeo85532_1694.

Phylogenomic databases

eggNOGiENOG4105BZ9. Bacteria.
COG0843. LUCA.
HOGENOMiHOG000085274.
InParanoidiO67935.
OMAiMDITTND.
OrthoDBiPOG091H042R.

Family and domain databases

Gene3Di1.20.210.10. 1 hit.
InterProiIPR000883. COX1.
IPR023616. Cyt_c_oxase-like_su1_dom.
IPR023615. Cyt_c_Oxase_su1_BS.
[Graphical view]
PANTHERiPTHR10422. PTHR10422. 1 hit.
PfamiPF00115. COX1. 1 hit.
[Graphical view]
PRINTSiPR01165. CYCOXIDASEI.
SUPFAMiSSF81442. SSF81442. 1 hit.
PROSITEiPS50855. COX1. 1 hit.
PS00077. COX1_CUB. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiO67935_AQUAE
AccessioniPrimary (citable) accession number: O67935
Entry historyi
Integrated into UniProtKB/TrEMBL: August 1, 1998
Last sequence update: August 1, 1998
Last modified: November 30, 2016
This is version 102 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.