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O67911

- O67911_AQUAE

UniProt

O67911 - O67911_AQUAE

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Protein
Submitted name:

Poly A polymerase

Gene
pcnB2, aq_2158
Organism
Aquifex aeolicus (strain VF5)
Status
Unreviewed - Annotation score: 3 out of 5 - Experimental evidence at protein leveli

Functioni

Catalytic activityi

A tRNA precursor + 2 CTP + ATP = a tRNA with a 3' CCA end + 3 diphosphate.SAAS annotations

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei45 – 451CTPImported
Binding sitei58 – 581CTPImported
Binding sitei137 – 1371CTP; via carbonyl oxygenImported
Binding sitei222 – 2221CTPImported

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi132 – 1332CTPImported
Nucleotide bindingi182 – 1887CTPImported

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. metal ion binding Source: InterPro
  3. nucleotidyltransferase activity Source: UniProtKB-KW
  4. phosphoric diester hydrolase activity Source: InterPro
  5. RNA binding Source: UniProtKB-KW

GO - Biological processi

  1. RNA processing Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

NucleotidyltransferaseSAAS annotations, Transferase

Keywords - Ligandi

ATP-bindingSAAS annotations, Nucleotide-binding, RNA-bindingUniRule annotationSAAS annotations

Enzyme and pathway databases

BioCyciAAEO224324:GJBH-1545-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Poly A polymeraseImported
Gene namesi
Name:pcnB2Imported
Ordered Locus Names:aq_2158Imported
OrganismiAquifex aeolicus (strain VF5)Imported
Taxonomic identifieri224324 [NCBI]
Taxonomic lineageiBacteriaAquificaeAquificalesAquificaceaeAquifex
ProteomesiUP000000798: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi224324.aq_2158.

Structurei

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3WFOX-ray3.40A/B/C1-512[»]
3WFPX-ray4.00A/B/C/D/E/F/G/H17-450[»]
3WFQX-ray3.62E/F/G/H16-448[»]
3WFRX-ray3.50E/F/G/H16-453[»]
3WFSX-ray3.31C/D16-448[»]
ProteinModelPortaliO67911.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

HOGENOMiHOG000062915.
KOiK00970.
OMAiKDVYAHS.
OrthoDBiEOG64R655.

Family and domain databases

InterProiIPR003607. HD/PDEase_dom.
IPR006674. HD_domain.
IPR002646. PolA_pol_head_dom.
IPR006675. Uncharacterised_HDIG.
[Graphical view]
PfamiPF01966. HD. 1 hit.
PF01743. PolyA_pol. 1 hit.
[Graphical view]
SMARTiSM00471. HDc. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00277. HDIG. 1 hit.

Sequencei

Sequence statusi: Complete.

O67911-1 [UniParc]FASTAAdd to Basket

« Hide

MENIEIVSSG KHTLHGLNFY LSYFDDVAKV LPREHYCFIV GGWVRDRILG    50
EPVGYNIDVD FLTTADPVEL AKNFAKRIGG HFFVFEKRGF LIKRPTIASV 100
VLHLPPYRYR FDFSPLKGKD LEKALIEDLK ERDFTANAIA VNLDDVLSIG 150
AKQTIVYDPT GGIKDLEQGL LRPVSIENLK RDPVRVLRGF RIAIEKNLQL 200
TEDFYEFVKE DPRIVLKSAV ERITHELFKI MKEKTAHKVI RELYEYGVLE 250
AIIPEIGRLR EVKDQGEHHI YPLDEHTLKT LEYLEQVIED RAKYLSAELL 300
ENFGKKRVLG EFTDVELLKW GALFHDIGKP QTFAVREGKV TFYEHDKVGA 350
QIVREIGERL RWGDEATEFV AKLVRHHLRP FFLREAFKKG ELKRRGMANF 400
WRECGDIAPH LFLLSIADAM ASGDEEEDIK ALMETIAELE SFNRNEMKEE 450
IQKPLLNGDE IMEILGIKPG KIVGILKKAL LEAQIDGKVE TKEEAIEFIK 500
RSTKNLKPLD EG 512
Length:512
Mass (Da):58,913
Last modified:August 1, 1998 - v1
Checksum:i58CDB8FD1A1B6F0F
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE000657 Genomic DNA. Translation: AAC07883.1.
PIRiC70485.
RefSeqiNP_214480.1. NC_000918.1.

Genome annotation databases

EnsemblBacteriaiAAC07883; AAC07883; aq_2158.
GeneIDi1193900.
KEGGiaae:aq_2158.
PATRICi20961154. VBIAquAeo85532_1668.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE000657 Genomic DNA. Translation: AAC07883.1 .
PIRi C70485.
RefSeqi NP_214480.1. NC_000918.1.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
3WFO X-ray 3.40 A/B/C 1-512 [» ]
3WFP X-ray 4.00 A/B/C/D/E/F/G/H 17-450 [» ]
3WFQ X-ray 3.62 E/F/G/H 16-448 [» ]
3WFR X-ray 3.50 E/F/G/H 16-453 [» ]
3WFS X-ray 3.31 C/D 16-448 [» ]
ProteinModelPortali O67911.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 224324.aq_2158.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAC07883 ; AAC07883 ; aq_2158 .
GeneIDi 1193900.
KEGGi aae:aq_2158.
PATRICi 20961154. VBIAquAeo85532_1668.

Phylogenomic databases

HOGENOMi HOG000062915.
KOi K00970.
OMAi KDVYAHS.
OrthoDBi EOG64R655.

Enzyme and pathway databases

BioCyci AAEO224324:GJBH-1545-MONOMER.

Family and domain databases

InterProi IPR003607. HD/PDEase_dom.
IPR006674. HD_domain.
IPR002646. PolA_pol_head_dom.
IPR006675. Uncharacterised_HDIG.
[Graphical view ]
Pfami PF01966. HD. 1 hit.
PF01743. PolyA_pol. 1 hit.
[Graphical view ]
SMARTi SM00471. HDc. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR00277. HDIG. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: VF5Imported.
  2. "Translocation and Rotation of tRNA during Template-Independent RNA Polymerization by tRNA Nucleotidyltransferase."
    Yamashita S., Takeshita D., Tomita K.
    Submitted (JUL-2013) to the PDB data bank
    Cited for: X-RAY CRYSTALLOGRAPHY (3.50 ANGSTROMS) OF 16-453 IN COMPLEX WITH CTP.

Entry informationi

Entry nameiO67911_AQUAE
AccessioniPrimary (citable) accession number: O67911
Entry historyi
Integrated into UniProtKB/TrEMBL: August 1, 1998
Last sequence update: August 1, 1998
Last modified: September 3, 2014
This is version 86 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureImported, Complete proteome, Reference proteome

External Data

Dasty 3

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