Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

O67911

- O67911_AQUAE

UniProt

O67911 - O67911_AQUAE

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Submitted name:

Poly A polymerase

Gene

pcnB2

Organism
Aquifex aeolicus (strain VF5)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli

Functioni

Catalytic activityi

A tRNA precursor + 2 CTP + ATP = a tRNA with a 3' CCA end + 3 diphosphate.SAAS annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei45 – 451CTPImported
Binding sitei58 – 581CTPImported
Binding sitei137 – 1371CTP; via carbonyl oxygenImported
Binding sitei222 – 2221CTPImported

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi132 – 1332CTPImported
Nucleotide bindingi182 – 1887CTPImported

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. nucleotidyltransferase activity Source: UniProtKB-KW
  3. RNA binding Source: UniProtKB-KW

GO - Biological processi

  1. RNA processing Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

NucleotidyltransferaseSAAS annotation, Transferase

Keywords - Ligandi

ATP-bindingSAAS annotation, Nucleotide-binding, RNA-bindingUniRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciAAEO224324:GJBH-1545-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Poly A polymeraseImported
Gene namesi
Name:pcnB2Imported
Ordered Locus Names:aq_2158Imported
OrganismiAquifex aeolicus (strain VF5)Imported
Taxonomic identifieri224324 [NCBI]
Taxonomic lineageiBacteriaAquificaeAquificalesAquificaceaeAquifex
ProteomesiUP000000798: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi224324.aq_2158.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3WFOX-ray3.40A/B/C1-512[»]
3WFPX-ray4.00A/B/C/D/E/F/G/H17-450[»]
3WFQX-ray3.62E/F/G/H16-448[»]
3WFRX-ray3.50E/F/G/H16-453[»]
3WFSX-ray3.31C/D16-448[»]
ProteinModelPortaliO67911.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000062915.
InParanoidiO67911.
KOiK00970.
OMAiKDVYAHS.
OrthoDBiEOG64R655.

Family and domain databases

InterProiIPR003607. HD/PDEase_dom.
IPR006674. HD_domain.
IPR002646. PolA_pol_head_dom.
IPR006675. Uncharacterised_HDIG.
[Graphical view]
PfamiPF01966. HD. 1 hit.
PF01743. PolyA_pol. 1 hit.
[Graphical view]
SMARTiSM00471. HDc. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00277. HDIG. 1 hit.

Sequencei

Sequence statusi: Complete.

O67911-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MENIEIVSSG KHTLHGLNFY LSYFDDVAKV LPREHYCFIV GGWVRDRILG
60 70 80 90 100
EPVGYNIDVD FLTTADPVEL AKNFAKRIGG HFFVFEKRGF LIKRPTIASV
110 120 130 140 150
VLHLPPYRYR FDFSPLKGKD LEKALIEDLK ERDFTANAIA VNLDDVLSIG
160 170 180 190 200
AKQTIVYDPT GGIKDLEQGL LRPVSIENLK RDPVRVLRGF RIAIEKNLQL
210 220 230 240 250
TEDFYEFVKE DPRIVLKSAV ERITHELFKI MKEKTAHKVI RELYEYGVLE
260 270 280 290 300
AIIPEIGRLR EVKDQGEHHI YPLDEHTLKT LEYLEQVIED RAKYLSAELL
310 320 330 340 350
ENFGKKRVLG EFTDVELLKW GALFHDIGKP QTFAVREGKV TFYEHDKVGA
360 370 380 390 400
QIVREIGERL RWGDEATEFV AKLVRHHLRP FFLREAFKKG ELKRRGMANF
410 420 430 440 450
WRECGDIAPH LFLLSIADAM ASGDEEEDIK ALMETIAELE SFNRNEMKEE
460 470 480 490 500
IQKPLLNGDE IMEILGIKPG KIVGILKKAL LEAQIDGKVE TKEEAIEFIK
510
RSTKNLKPLD EG
Length:512
Mass (Da):58,913
Last modified:August 1, 1998 - v1
Checksum:i58CDB8FD1A1B6F0F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000657 Genomic DNA. Translation: AAC07883.1.
PIRiC70485.
RefSeqiNP_214480.1. NC_000918.1.
WP_010881416.1. NC_000918.1.

Genome annotation databases

EnsemblBacteriaiAAC07883; AAC07883; aq_2158.
GeneIDi1193900.
KEGGiaae:aq_2158.
PATRICi20961154. VBIAquAeo85532_1668.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000657 Genomic DNA. Translation: AAC07883.1 .
PIRi C70485.
RefSeqi NP_214480.1. NC_000918.1.
WP_010881416.1. NC_000918.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
3WFO X-ray 3.40 A/B/C 1-512 [» ]
3WFP X-ray 4.00 A/B/C/D/E/F/G/H 17-450 [» ]
3WFQ X-ray 3.62 E/F/G/H 16-448 [» ]
3WFR X-ray 3.50 E/F/G/H 16-453 [» ]
3WFS X-ray 3.31 C/D 16-448 [» ]
ProteinModelPortali O67911.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 224324.aq_2158.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAC07883 ; AAC07883 ; aq_2158 .
GeneIDi 1193900.
KEGGi aae:aq_2158.
PATRICi 20961154. VBIAquAeo85532_1668.

Phylogenomic databases

HOGENOMi HOG000062915.
InParanoidi O67911.
KOi K00970.
OMAi KDVYAHS.
OrthoDBi EOG64R655.

Enzyme and pathway databases

BioCyci AAEO224324:GJBH-1545-MONOMER.

Family and domain databases

InterProi IPR003607. HD/PDEase_dom.
IPR006674. HD_domain.
IPR002646. PolA_pol_head_dom.
IPR006675. Uncharacterised_HDIG.
[Graphical view ]
Pfami PF01966. HD. 1 hit.
PF01743. PolyA_pol. 1 hit.
[Graphical view ]
SMARTi SM00471. HDc. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR00277. HDIG. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: VF5Imported.
  2. "Translocation and rotation of tRNA during template-independent RNA polymerization by tRNA nucleotidyltransferase."
    Yamashita S., Takeshita D., Tomita K.
    Structure 22:315-325(2014) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (3.31 ANGSTROMS) OF 16-448 IN COMPLEX WITH CTP.

Entry informationi

Entry nameiO67911_AQUAE
AccessioniPrimary (citable) accession number: O67911
Entry historyi
Integrated into UniProtKB/TrEMBL: August 1, 1998
Last sequence update: August 1, 1998
Last modified: October 29, 2014
This is version 88 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureImported, Complete proteome, Reference proteomeImported

External Data

Dasty 3