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Protein

Glycine--tRNA ligase beta subunit

Gene

glyS

Organism
Aquifex aeolicus (strain VF5)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly).

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Aminoacyl-tRNA synthetase, Ligase

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Glycine--tRNA ligase beta subunit (EC:6.1.1.14)
Alternative name(s):
Glycyl-tRNA synthetase beta subunit
Short name:
GlyRS
Gene namesi
Name:glyS
Ordered Locus Names:aq_2141
OrganismiAquifex aeolicus (strain VF5)
Taxonomic identifieri224324 [NCBI]
Taxonomic lineageiBacteriaAquificaeAquificalesAquificaceaeAquifex
Proteomesi
  • UP000000798 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000728921 – 664Glycine--tRNA ligase beta subunitAdd BLAST664

Interactioni

Subunit structurei

Tetramer of two alpha and two beta subunits.By similarity

Protein-protein interaction databases

STRINGi224324.aq_2141.

Structurei

3D structure databases

ProteinModelPortaliO67898.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiENOG4107RFA. Bacteria.
COG0751. LUCA.
HOGENOMiHOG000264303.
InParanoidiO67898.
KOiK01879.
OMAiIVFHAKL.
OrthoDBiPOG091H00US.

Family and domain databases

HAMAPiMF_00255. Gly_tRNA_synth_beta. 1 hit.
InterProiIPR008909. DALR_anticod-bd.
IPR015944. Gly-tRNA-synth_bsu.
IPR006194. Gly-tRNA-synth_heterodimer.
[Graphical view]
PfamiPF05746. DALR_1. 1 hit.
PF02092. tRNA_synt_2f. 1 hit.
[Graphical view]
PRINTSiPR01045. TRNASYNTHGB.
TIGRFAMsiTIGR00211. glyS. 1 hit.
PROSITEiPS50861. AA_TRNA_LIGASE_II_GLYAB. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O67898-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTNELLIEIG TEELPAGVIN PALDYLKDKI NSLLNARQVK TYGTPRRLTL
60 70 80 90 100
YFKDFENERK EKKEVIWGPP KNVAYDEKGN PTKALEGFLK KNNASLEEVK
110 120 130 140 150
VLKKDKGEYV AIVRKVIEKS PIEKLQEEFE EILLSVPFPK RMRWTSSKRI
160 170 180 190 200
TFSRPVRWIL ALFNGQVLKL RFGELESSNK TYGHRFLSKG EVTINNPADY
210 220 230 240 250
EKTLKEHYVI PDFNERKEII LRALEKSSQE VGGKPSYPEG LVEEVTNLVE
260 270 280 290 300
YPFPVLGKFD EKYLELPPLV ITTVAAHHQR FFCFEKDGKL LNYFLGISNN
310 320 330 340 350
KPNEKIKEGY EKVLRARLED ALFFYREDLK KDLKSLIPEL KKVLFHPKVG
360 370 380 390 400
SMYEKEERME KIAQKLCPLL KCEWEKVKEA VWLSKVDLLT EMVKELDELQ
410 420 430 440 450
GYMGYVYAKA QGYDEEVAKA LWEQYFPRSL EDKVPETTTG TILSLSDKID
460 470 480 490 500
NLYSFFKAGE IPKGSSDPYG LRRSAFGIIK IVDVKNLDLN LEDFKEIYGE
510 520 530 540 550
FKQYPKLVEF LKQRLISYLE DYPVDIVRAV LNVYSPMEPY KVINSVRVLY
560 570 580 590 600
EASKSPEFPS VVEAAKRVIR IIPKDWKNYE VDEKLLSEEA ERELYQKLTE
610 620 630 640 650
FENKELKSPL ELLPLKEYID KFFDNVKVMA EDEKIRNNRI SLLKRVENLF
660
RTFGDFNEIV IKEG
Length:664
Mass (Da):77,524
Last modified:August 1, 1998 - v1
Checksum:i7FFEF7A8F552E3DB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000657 Genomic DNA. Translation: AAC07870.1.
PIRiF70483.
RefSeqiNP_214467.1. NC_000918.1.
WP_010881403.1. NC_000918.1.

Genome annotation databases

EnsemblBacteriaiAAC07870; AAC07870; aq_2141.
GeneIDi1193887.
KEGGiaae:aq_2141.
PATRICi20961124. VBIAquAeo85532_1655.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000657 Genomic DNA. Translation: AAC07870.1.
PIRiF70483.
RefSeqiNP_214467.1. NC_000918.1.
WP_010881403.1. NC_000918.1.

3D structure databases

ProteinModelPortaliO67898.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi224324.aq_2141.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC07870; AAC07870; aq_2141.
GeneIDi1193887.
KEGGiaae:aq_2141.
PATRICi20961124. VBIAquAeo85532_1655.

Phylogenomic databases

eggNOGiENOG4107RFA. Bacteria.
COG0751. LUCA.
HOGENOMiHOG000264303.
InParanoidiO67898.
KOiK01879.
OMAiIVFHAKL.
OrthoDBiPOG091H00US.

Family and domain databases

HAMAPiMF_00255. Gly_tRNA_synth_beta. 1 hit.
InterProiIPR008909. DALR_anticod-bd.
IPR015944. Gly-tRNA-synth_bsu.
IPR006194. Gly-tRNA-synth_heterodimer.
[Graphical view]
PfamiPF05746. DALR_1. 1 hit.
PF02092. tRNA_synt_2f. 1 hit.
[Graphical view]
PRINTSiPR01045. TRNASYNTHGB.
TIGRFAMsiTIGR00211. glyS. 1 hit.
PROSITEiPS50861. AA_TRNA_LIGASE_II_GLYAB. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiSYGB_AQUAE
AccessioniPrimary (citable) accession number: O67898
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: August 1, 1998
Last modified: November 2, 2016
This is version 103 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.