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O67853

- TRPF_AQUAE

UniProt

O67853 - TRPF_AQUAE

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Protein

N-(5'-phosphoribosyl)anthranilate isomerase

Gene
trpF, aq_2076
Organism
Aquifex aeolicus (strain VF5)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. phosphoribosylanthranilate isomerase activity Source: UniProtKB-EC

GO - Biological processi

  1. tryptophan biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Amino-acid biosynthesis, Aromatic amino acid biosynthesis, Tryptophan biosynthesis

Enzyme and pathway databases

BioCyciAAEO224324:GJBH-1485-MONOMER.
UniPathwayiUPA00035; UER00042.

Names & Taxonomyi

Protein namesi
Recommended name:
N-(5'-phosphoribosyl)anthranilate isomerase (EC:5.3.1.24)
Short name:
PRAI
Gene namesi
Name:trpF
Ordered Locus Names:aq_2076
OrganismiAquifex aeolicus (strain VF5)
Taxonomic identifieri224324 [NCBI]
Taxonomic lineageiBacteriaAquificaeAquificalesAquificaceaeAquifex
ProteomesiUP000000798: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 204204N-(5'-phosphoribosyl)anthranilate isomeraseUniRule annotationPRO_0000154342Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi224324.aq_2076.

Structurei

3D structure databases

ProteinModelPortaliO67853.

Family & Domainsi

Sequence similaritiesi

Belongs to the TrpF family.

Phylogenomic databases

eggNOGiCOG0135.
HOGENOMiHOG000161598.
KOiK01817.
OMAiHIMANSG.
OrthoDBiEOG6N94DF.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
HAMAPiMF_00135. PRAI.
InterProiIPR013785. Aldolase_TIM.
IPR001240. PRAI_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view]
PfamiPF00697. PRAI. 1 hit.
[Graphical view]
SUPFAMiSSF51366. SSF51366. 1 hit.

Sequencei

Sequence statusi: Complete.

O67853-1 [UniParc]FASTAAdd to Basket

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MVKVKICGIT NLEDALFCAK EGADYIGVIT YPKSPRYTSK EKRLEIIKAL    50
EGLNVKKVAV VVNEPYEFIK ELLDEGFDLI QLHGDEDIEL GKRVGLDKVI 100
KVFRVKEEIP KVGEWEKAYA ILLDTFSKEA YGGTGKTFNW EIAKKLVEEG 150
HKVFLSGGLN PENVKEGIEF VKPYGVDVSS GVEKEKGKKD FKKVREFIKR 200
TKSE 204
Length:204
Mass (Da):23,061
Last modified:August 1, 1998 - v1
Checksum:iFDEA387E0602A10E
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE000657 Genomic DNA. Translation: AAC07811.1.
PIRiA70478.
RefSeqiNP_214422.1. NC_000918.1.

Genome annotation databases

EnsemblBacteriaiAAC07811; AAC07811; aq_2076.
GeneIDi1193842.
KEGGiaae:aq_2076.
PATRICi20961012. VBIAquAeo85532_1599.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE000657 Genomic DNA. Translation: AAC07811.1 .
PIRi A70478.
RefSeqi NP_214422.1. NC_000918.1.

3D structure databases

ProteinModelPortali O67853.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 224324.aq_2076.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAC07811 ; AAC07811 ; aq_2076 .
GeneIDi 1193842.
KEGGi aae:aq_2076.
PATRICi 20961012. VBIAquAeo85532_1599.

Phylogenomic databases

eggNOGi COG0135.
HOGENOMi HOG000161598.
KOi K01817.
OMAi HIMANSG.
OrthoDBi EOG6N94DF.

Enzyme and pathway databases

UniPathwayi UPA00035 ; UER00042 .
BioCyci AAEO224324:GJBH-1485-MONOMER.

Family and domain databases

Gene3Di 3.20.20.70. 1 hit.
HAMAPi MF_00135. PRAI.
InterProi IPR013785. Aldolase_TIM.
IPR001240. PRAI_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view ]
Pfami PF00697. PRAI. 1 hit.
[Graphical view ]
SUPFAMi SSF51366. SSF51366. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: VF5.

Entry informationi

Entry nameiTRPF_AQUAE
AccessioniPrimary (citable) accession number: O67853
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: August 1, 1998
Last modified: May 14, 2014
This is version 82 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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