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O67853

- TRPF_AQUAE

UniProt

O67853 - TRPF_AQUAE

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Protein

N-(5'-phosphoribosyl)anthranilate isomerase

Gene

trpF

Organism
Aquifex aeolicus (strain VF5)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate.

Pathwayi

GO - Molecular functioni

  1. phosphoribosylanthranilate isomerase activity Source: UniProtKB-EC

GO - Biological processi

  1. tryptophan biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Amino-acid biosynthesis, Aromatic amino acid biosynthesis, Tryptophan biosynthesis

Enzyme and pathway databases

BioCyciAAEO224324:GJBH-1485-MONOMER.
UniPathwayiUPA00035; UER00042.

Names & Taxonomyi

Protein namesi
Recommended name:
N-(5'-phosphoribosyl)anthranilate isomerase (EC:5.3.1.24)
Short name:
PRAI
Gene namesi
Name:trpF
Ordered Locus Names:aq_2076
OrganismiAquifex aeolicus (strain VF5)
Taxonomic identifieri224324 [NCBI]
Taxonomic lineageiBacteriaAquificaeAquificalesAquificaceaeAquifex
ProteomesiUP000000798: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 204204N-(5'-phosphoribosyl)anthranilate isomerasePRO_0000154342Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi224324.aq_2076.

Structurei

3D structure databases

ProteinModelPortaliO67853.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the TrpF family.Curated

Phylogenomic databases

eggNOGiCOG0135.
HOGENOMiHOG000161598.
InParanoidiO67853.
KOiK01817.
OMAiHIMANSG.
OrthoDBiEOG6N94DF.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
HAMAPiMF_00135. PRAI.
InterProiIPR013785. Aldolase_TIM.
IPR001240. PRAI_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view]
PfamiPF00697. PRAI. 1 hit.
[Graphical view]
SUPFAMiSSF51366. SSF51366. 1 hit.

Sequencei

Sequence statusi: Complete.

O67853-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MVKVKICGIT NLEDALFCAK EGADYIGVIT YPKSPRYTSK EKRLEIIKAL
60 70 80 90 100
EGLNVKKVAV VVNEPYEFIK ELLDEGFDLI QLHGDEDIEL GKRVGLDKVI
110 120 130 140 150
KVFRVKEEIP KVGEWEKAYA ILLDTFSKEA YGGTGKTFNW EIAKKLVEEG
160 170 180 190 200
HKVFLSGGLN PENVKEGIEF VKPYGVDVSS GVEKEKGKKD FKKVREFIKR

TKSE
Length:204
Mass (Da):23,061
Last modified:August 1, 1998 - v1
Checksum:iFDEA387E0602A10E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000657 Genomic DNA. Translation: AAC07811.1.
PIRiA70478.
RefSeqiNP_214422.1. NC_000918.1.
WP_010881358.1. NC_000918.1.

Genome annotation databases

EnsemblBacteriaiAAC07811; AAC07811; aq_2076.
GeneIDi1193842.
KEGGiaae:aq_2076.
PATRICi20961012. VBIAquAeo85532_1599.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000657 Genomic DNA. Translation: AAC07811.1 .
PIRi A70478.
RefSeqi NP_214422.1. NC_000918.1.
WP_010881358.1. NC_000918.1.

3D structure databases

ProteinModelPortali O67853.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 224324.aq_2076.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAC07811 ; AAC07811 ; aq_2076 .
GeneIDi 1193842.
KEGGi aae:aq_2076.
PATRICi 20961012. VBIAquAeo85532_1599.

Phylogenomic databases

eggNOGi COG0135.
HOGENOMi HOG000161598.
InParanoidi O67853.
KOi K01817.
OMAi HIMANSG.
OrthoDBi EOG6N94DF.

Enzyme and pathway databases

UniPathwayi UPA00035 ; UER00042 .
BioCyci AAEO224324:GJBH-1485-MONOMER.

Family and domain databases

Gene3Di 3.20.20.70. 1 hit.
HAMAPi MF_00135. PRAI.
InterProi IPR013785. Aldolase_TIM.
IPR001240. PRAI_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view ]
Pfami PF00697. PRAI. 1 hit.
[Graphical view ]
SUPFAMi SSF51366. SSF51366. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: VF5.

Entry informationi

Entry nameiTRPF_AQUAE
AccessioniPrimary (citable) accession number: O67853
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: August 1, 1998
Last modified: October 29, 2014
This is version 84 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3