O67802 (DLHH_AQUAE) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative carboxymethylenebutenolidase
EC=3.1.1.45

Alternative name(s):
Dienelactone hydrolase
Short name=DLH

Gene names

Ordered Locus Names:

aq_1997

Organism

Aquifex aeolicus (strain VF5)

Taxonomic identifier

224324 [NCBI]

Taxonomic lineage

Bacteria › Aquificae › Aquificales › Aquificaceae › Aquifex

Protein attributes

Sequence length	231 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	4-carboxymethylenebut-2-en-4-olide + H2O = 4-oxohex-2-enedioate.
Sequence similarities	Belongs to the dienelactone hydrolase family.

Ontologies

Keywords
Molecular function	Hydrolase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Molecular function	carboxymethylenebutenolidase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 231	231	Putative carboxymethylenebutenolidase		PRO_0000161576
Sites
	Active site	118	1	By similarity
	Active site	167	1	By similarity
	Active site	199	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	O67802 [UniParc]. Last modified August 1, 1998. Version 1. Checksum: 8268DA32A6980751	FASTA	231	26,357
	10 20 30 40 50 60 MGQMVEFEKN GVKVRGYIAT PKWAGPAVLV FHEWWGLESP LSNIKEICDK LADEGFVAFA 70 80 90 100 110 120 PDFYKGQYAD NPDDAGKLMT EMFEKRMDEV DRIFQASVEF VKECRYTYPK KVGITGFCCG 130 140 150 160 170 180 GTLAMYFAAK FPEMVDASLP FYGLPQLTQI NAENIKVPIF FILAEKDEFV NNDEVIDIAK 190 200 210 220 230 TVWKNGVDVQ VKVFSGVTHA FLNEKREDVY DPKRACEAWE LAVNFFKTYL K

References

[1]

"The complete genome of the hyperthermophilic bacterium Aquifex aeolicus." Deckert G., Warren P.V., Gaasterland T., Young W.G., Lenox A.L., Graham D.E., Overbeek R., Snead M.A., Keller M., Aujay M., Huber R., Feldman R.A., Short J.M., Olsen G.J., Swanson R.V. Nature 392:353-358(1998) [PubMed: 9537320] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: VF5.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE000657 Genomic DNA. Translation: AAC07773.1.
PIR	F70471.
RefSeq	NP_214371.1. NC_000918.1.
3D structure databases
ProteinModelPortal	O67802.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1193699.
GenomeReviews	Gene locus aq_1997 in contig AE000657_GR.
KEGG	aae:aq_1997.
NMPDR	fig|224324.1.peg.1386.
PATRIC	20960898. VBIAquAeo85532_1544.
Phylogenomic databases
HOGENOM	HBG673102.
OMA	TWMTRYL.
PhylomeDB	O67802.
ProtClustDB	CLSK2299900.
Enzyme and pathway databases
BioCyc	AAEO224324:AQ_1997-MONOMER.
Family and domain databases
InterPro	IPR002925. Dienelactn_hydro. [Graphical view]
KO	K01061.
Pfam	PF01738. DLH. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

DLHH_AQUAE

Accession

Primary (citable) accession number: O67802

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 15, 1998
Last sequence update:	August 1, 1998
Last modified:	January 25, 2012
This is version 63 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program