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Protein

Transcription termination/antitermination protein NusG

Gene

nusG

Organism
Aquifex aeolicus (strain VF5)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Participates in transcription elongation, termination and antitermination.UniRule annotation

GO - Biological processi

Keywordsi

Biological processTranscription, Transcription antitermination, Transcription regulation, Transcription termination

Enzyme and pathway databases

BioCyciAAEO224324:G1G15-1384-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Transcription termination/antitermination protein NusGUniRule annotation
Gene namesi
Name:nusGUniRule annotation
Ordered Locus Names:aq_1931
OrganismiAquifex aeolicus (strain VF5)
Taxonomic identifieri224324 [NCBI]
Taxonomic lineageiBacteriaAquificaeAquificalesAquificaceaeAquifex
Proteomesi
  • UP000000798 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Pathology & Biotechi

Chemistry databases

DrugBankiDB02325 Isopropyl Alcohol

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001139141 – 248Transcription termination/antitermination protein NusGAdd BLAST248

Interactioni

Subunit structurei

Monomer (PubMed:12198166). Homodimer (PubMed:12600194).2 Publications

Protein-protein interaction databases

STRINGi224324.aq_1931

Structurei

Secondary structure

1248
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi12 – 18Combined sources7
Helixi23 – 36Combined sources14
Helixi40 – 42Combined sources3
Beta strandi43 – 47Combined sources5
Beta strandi49 – 58Combined sources10
Beta strandi61 – 71Combined sources11
Beta strandi73 – 78Combined sources6
Beta strandi80 – 88Combined sources9
Beta strandi93 – 97Combined sources5
Helixi103 – 106Combined sources4
Beta strandi116 – 119Combined sources4
Turni120 – 123Combined sources4
Beta strandi124 – 131Combined sources8
Beta strandi133 – 135Combined sources3
Beta strandi138 – 143Combined sources6
Helixi147 – 154Combined sources8
Beta strandi159 – 162Combined sources4
Beta strandi164 – 169Combined sources6
Helixi174 – 183Combined sources10
Beta strandi200 – 203Combined sources4
Turni207 – 210Combined sources4
Beta strandi212 – 219Combined sources8
Turni220 – 223Combined sources4
Beta strandi224 – 231Combined sources8
Beta strandi234 – 241Combined sources8
Beta strandi244 – 248Combined sources5

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1M1GX-ray2.00A/B/C/D1-248[»]
1M1HX-ray1.95A1-248[»]
1NPPX-ray2.00A/B/C/D1-248[»]
1NPRX-ray2.21A1-248[»]
ProteinModelPortaliO67757
SMRiO67757
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiO67757

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini197 – 227KOWUniRule annotationAdd BLAST31

Domaini

Contains an N-terminal RNP-like domain, a C-terminal element with a KOW sequence motif and a species-specific immunoglobulin-like fold.1 Publication

Sequence similaritiesi

Belongs to the NusG family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4107WP1 Bacteria
COG0250 LUCA
HOGENOMiHOG000219265
InParanoidiO67757
KOiK02601
OMAiIEGPFMN
OrthoDBiPOG091H02IB

Family and domain databases

Gene3Di2.30.30.30, 1 hit
2.60.320.10, 1 hit
3.30.70.940, 2 hits
HAMAPiMF_00948 NusG, 1 hit
InterProiView protein in InterPro
IPR005824 KOW
IPR006645 NGN_dom
IPR036735 NGN_dom_sf
IPR038690 NusG_2_sf
IPR024045 NusG_dom2
IPR014722 Rib_L2_dom2
IPR001062 Transcrpt_antiterm_NusG
IPR015869 Transcrpt_antiterm_NusG_bac_CS
IPR008991 Translation_prot_SH3-like_sf
PANTHERiPTHR30265:SF2 PTHR30265:SF2, 1 hit
PfamiView protein in Pfam
PF00467 KOW, 1 hit
PF02357 NusG, 1 hit
PF07009 NusG_II, 1 hit
PRINTSiPR00338 NUSGTNSCPFCT
SMARTiView protein in SMART
SM00739 KOW, 1 hit
SM00738 NGN, 1 hit
SUPFAMiSSF50104 SSF50104, 1 hit
SSF82679 SSF82679, 2 hits
TIGRFAMsiTIGR00922 nusG, 1 hit
PROSITEiView protein in PROSITE
PS01014 NUSG, 1 hit

Sequencei

Sequence statusi: Complete.

O67757-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSEQQVQELE KKWYALQVEP GKENEAKENL LKVLELEGLK DLVDEVIVPA
60 70 80 90 100
EEKVVIRAQG KEKYRLSLKG NARDISVLGK KGVTTFRIEN GEVKVVESVE
110 120 130 140 150
GDTCVNAPPI SKPGQKITCK ENKTEAKIVL DNKIFPGYIL IKAHMNDKLL
160 170 180 190 200
MAIEKTPHVF RPVMVGGKPV PLKEEEVQNI LNQIKRGVKP SKVEFEKGDQ
210 220 230 240
VRVIEGPFMN FTGTVEEVHP EKRKLTVMIS IFGRMTPVEL DFDQVEKI
Length:248
Mass (Da):27,999
Last modified:August 1, 1998 - v1
Checksum:iCECE083CA19D8482
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000657 Genomic DNA Translation: AAC07722.1
PIRiA70466
RefSeqiNP_214326.1, NC_000918.1
WP_010881262.1, NC_000918.1

Genome annotation databases

EnsemblBacteriaiAAC07722; AAC07722; aq_1931
GeneIDi1193654
KEGGiaae:aq_1931
PATRICifig|224324.8.peg.1496

Similar proteinsi

Entry informationi

Entry nameiNUSG_AQUAE
AccessioniPrimary (citable) accession number: O67757
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 20, 2001
Last sequence update: August 1, 1998
Last modified: April 25, 2018
This is version 122 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

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