Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Deoxycytidine triphosphate deaminase

Gene

dcd

Organism
Aquifex aeolicus (strain VF5)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

dCTP + H2O = dUTP + NH3.

Pathwayi

GO - Molecular functioni

  1. dCTP deaminase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. dUMP biosynthetic process Source: UniProtKB-UniPathway
  2. dUTP biosynthetic process Source: InterPro
  3. pyrimidine ribonucleotide biosynthetic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Biological processi

Nucleotide metabolism

Enzyme and pathway databases

BioCyciAAEO224324:GJBH-1146-MONOMER.
UniPathwayiUPA00610; UER00665.

Names & Taxonomyi

Protein namesi
Recommended name:
Deoxycytidine triphosphate deaminase (EC:3.5.4.13)
Short name:
dCTP deaminase
Gene namesi
Name:dcd
Ordered Locus Names:aq_1607
OrganismiAquifex aeolicus (strain VF5)
Taxonomic identifieri224324 [NCBI]
Taxonomic lineageiBacteriaAquificaeAquificalesAquificaceaeAquifex
ProteomesiUP000000798: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 180180Deoxycytidine triphosphate deaminasePRO_0000155963Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi224324.aq_1607.

Structurei

3D structure databases

ProteinModelPortaliO67539.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the dCTP deaminase family.Curated

Phylogenomic databases

eggNOGiCOG0717.
HOGENOMiHOG000228601.
InParanoidiO67539.
KOiK01494.
OMAiGWIDAGF.
OrthoDBiEOG67DPKR.

Family and domain databases

Gene3Di2.70.40.10. 1 hit.
HAMAPiMF_00146. dCTP_deaminase.
InterProiIPR011962. dCTP_deam.
IPR029054. dUTPase-like.
IPR008180. dUTPase/dCTP_deaminase.
[Graphical view]
PfamiPF00692. dUTPase. 1 hit.
[Graphical view]
SUPFAMiSSF51283. SSF51283. 1 hit.
TIGRFAMsiTIGR02274. dCTP_deam. 1 hit.

Sequencei

Sequence statusi: Complete.

O67539-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MILSDRSIRE LIEKGELKVE PYEPSHVQCS SLDLRLGNQI ALYEGEGVID
60 70 80 90 100
VKKGTKGVRI LEFEEYFDIM PKQFLLATTL EYISLPPYVT AFVEGRSSLG
110 120 130 140 150
RLGLFIENAG WVDAGFEGQI TLELFNANDR PIRLYRGMRI CQLVFARLDR
160 170 180
PPERVYSGKY KGQKGVVPSR IHMDEELKSE
Length:180
Mass (Da):20,545
Last modified:August 1, 1998 - v1
Checksum:iB2710421A2FA48D6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000657 Genomic DNA. Translation: AAC07499.1.
PIRiA70439.
RefSeqiNP_214104.1. NC_000918.1.

Genome annotation databases

EnsemblBacteriaiAAC07499; AAC07499; aq_1607.
GeneIDi1193162.
KEGGiaae:aq_1607.
PATRICi20960256. VBIAquAeo85532_1241.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000657 Genomic DNA. Translation: AAC07499.1.
PIRiA70439.
RefSeqiNP_214104.1. NC_000918.1.

3D structure databases

ProteinModelPortaliO67539.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi224324.aq_1607.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC07499; AAC07499; aq_1607.
GeneIDi1193162.
KEGGiaae:aq_1607.
PATRICi20960256. VBIAquAeo85532_1241.

Phylogenomic databases

eggNOGiCOG0717.
HOGENOMiHOG000228601.
InParanoidiO67539.
KOiK01494.
OMAiGWIDAGF.
OrthoDBiEOG67DPKR.

Enzyme and pathway databases

UniPathwayiUPA00610; UER00665.
BioCyciAAEO224324:GJBH-1146-MONOMER.

Family and domain databases

Gene3Di2.70.40.10. 1 hit.
HAMAPiMF_00146. dCTP_deaminase.
InterProiIPR011962. dCTP_deam.
IPR029054. dUTPase-like.
IPR008180. dUTPase/dCTP_deaminase.
[Graphical view]
PfamiPF00692. dUTPase. 1 hit.
[Graphical view]
SUPFAMiSSF51283. SSF51283. 1 hit.
TIGRFAMsiTIGR02274. dCTP_deam. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: VF5.

Entry informationi

Entry nameiDCD_AQUAE
AccessioniPrimary (citable) accession number: O67539
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: August 1, 1998
Last modified: March 4, 2015
This is version 90 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.