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Protein
Submitted name:

Cytochrome c552

Gene

cycB2

Organism
Aquifex aeolicus (strain VF5)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei29 – 291Heme (covalent)Combined sources
Binding sitei32 – 321Heme (covalent)Combined sources
Metal bindingi33 – 331Iron (heme axial ligand); via tele nitrogenCombined sources
Metal bindingi78 – 781Iron (heme axial ligand)Combined sources

GO - Molecular functioni

Complete GO annotation...

Keywords - Ligandi

HemeCombined sources, Iron, Metal-binding

Enzyme and pathway databases

BioCyciAAEO224324:GJBH-1111-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Cytochrome c552Imported
Gene namesi
Name:cycB2Imported
Ordered Locus Names:aq_1550Imported
OrganismiAquifex aeolicus (strain VF5)Imported
Taxonomic identifieri224324 [NCBI]
Taxonomic lineageiBacteriaAquificaeAquificalesAquificaceaeAquifex
Proteomesi
  • UP000000798 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1717Sequence analysisAdd
BLAST
Chaini18 – 10487Sequence analysisPRO_5004159543Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi224324.aq_1550.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2ZXYX-ray1.15A18-104[»]
3X15X-ray1.60A/D/G/J18-104[»]
ProteinModelPortaliO67504.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiO67504.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini15 – 10490Cytochrome cInterPro annotationAdd
BLAST

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG4106BXD. Bacteria.
COG4654. LUCA.
HOGENOMiHOG000254790.
InParanoidiO67504.
KOiK08738.
OMAiKVIGPSI.
OrthoDBiEOG6677VJ.

Family and domain databases

Gene3Di1.10.760.10. 1 hit.
InterProiIPR009056. Cyt_c-like_dom.
IPR002324. Cyt_c_ID.
[Graphical view]
PfamiPF00034. Cytochrom_C. 1 hit.
[Graphical view]
PRINTSiPR00606. CYTCHROMECID.
SUPFAMiSSF46626. SSF46626. 1 hit.
PROSITEiPS51007. CYTC. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O67504-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKKLLLAGLA VAGLTFAADG KAIFQQKGCG SCHQANVDTV GPSLKKIAQA
60 70 80 90 100
YAGKEDQLIK FLKGEAPAIV DPAKEAIMKP QLTMLKGLSD AELKALADFI

LSHK
Length:104
Mass (Da):10,950
Last modified:August 1, 1998 - v1
Checksum:i9AADAB6D445FD07C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000657 Genomic DNA. Translation: AAC07464.1.
PIRiF70434.
RefSeqiNP_214069.1. NC_000918.1.
WP_010881007.1. NC_000918.1.

Genome annotation databases

EnsemblBacteriaiAAC07464; AAC07464; aq_1550.
GeneIDi1193127.
KEGGiaae:aq_1550.
PATRICi20960180. VBIAquAeo85532_1203.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000657 Genomic DNA. Translation: AAC07464.1.
PIRiF70434.
RefSeqiNP_214069.1. NC_000918.1.
WP_010881007.1. NC_000918.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2ZXYX-ray1.15A18-104[»]
3X15X-ray1.60A/D/G/J18-104[»]
ProteinModelPortaliO67504.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi224324.aq_1550.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC07464; AAC07464; aq_1550.
GeneIDi1193127.
KEGGiaae:aq_1550.
PATRICi20960180. VBIAquAeo85532_1203.

Phylogenomic databases

eggNOGiENOG4106BXD. Bacteria.
COG4654. LUCA.
HOGENOMiHOG000254790.
InParanoidiO67504.
KOiK08738.
OMAiKVIGPSI.
OrthoDBiEOG6677VJ.

Enzyme and pathway databases

BioCyciAAEO224324:GJBH-1111-MONOMER.

Miscellaneous databases

EvolutionaryTraceiO67504.

Family and domain databases

Gene3Di1.10.760.10. 1 hit.
InterProiIPR009056. Cyt_c-like_dom.
IPR002324. Cyt_c_ID.
[Graphical view]
PfamiPF00034. Cytochrom_C. 1 hit.
[Graphical view]
PRINTSiPR00606. CYTCHROMECID.
SUPFAMiSSF46626. SSF46626. 1 hit.
PROSITEiPS51007. CYTC. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: VF5Imported.
  2. "Hyperstability and crystal structure of cytochrome c(555) from hyperthermophilic Aquifex aeolicus."
    Obuchi M., Kawahara K., Motooka D., Nakamura S., Yamanaka M., Takeda T., Uchiyama S., Kobayashi Y., Ohkubo T., Sambongi Y.
    Acta Crystallogr. D 65:804-813(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (1.15 ANGSTROMS) OF 18-104 IN COMPLEX WITH HEME.
  3. "Change in structure and ligand binding properties of hyperstable cytochrome c555 from Aquifex aeolicus by domain swapping."
    Yamanaka M., Nagao S., Komori H., Higuchi Y., Hirota S.
    Protein Sci. 24:366-375(2015) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (1.60 ANGSTROMS) OF 18-104 IN COMPLEX WITH HEME.

Entry informationi

Entry nameiO67504_AQUAE
AccessioniPrimary (citable) accession number: O67504
Entry historyi
Integrated into UniProtKB/TrEMBL: August 1, 1998
Last sequence update: August 1, 1998
Last modified: March 16, 2016
This is version 102 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.