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Protein
Submitted name:

Uncharacterized protein

Gene

aq_1447

Organism
Aquifex aeolicus (strain VF5)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi502 – 5021CalciumCombined sources
Metal bindingi683 – 6831CalciumCombined sources

GO - Molecular functioni

Complete GO annotation...

Keywords - Ligandi

CalciumCombined sources, Metal-bindingCombined sources

Enzyme and pathway databases

BioCyciAAEO224324:GJBH-1040-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Ordered Locus Names:aq_1447Imported
OrganismiAquifex aeolicus (strain VF5)Imported
Taxonomic identifieri224324 [NCBI]
Taxonomic lineageiBacteriaAquificaeAquificalesAquificaceaeAquifex
Proteomesi
  • UP000000798 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

DIPiDIP-29161N.
STRINGi224324.aq_1447.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1YVUX-ray2.90A1-706[»]
2F8SX-ray3.00A/B1-706[»]
2F8TX-ray3.10A/B1-706[»]
2NUBX-ray3.20A1-706[»]
ProteinModelPortaliO67434.
SMRiO67434. Positions 3-706.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiO67434.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini419 – 694276PiwiInterPro annotationAdd
BLAST

Phylogenomic databases

eggNOGiENOG4108X5X. Bacteria.
COG1431. LUCA.
InParanoidiO67434.
KOiK07578.
OrthoDBiEOG6DG2QH.

Family and domain databases

Gene3Di3.30.420.10. 1 hit.
InterProiIPR003100. PAZ_dom.
IPR003165. Piwi.
IPR012337. RNaseH-like_dom.
[Graphical view]
PfamiPF02171. Piwi. 1 hit.
[Graphical view]
SMARTiSM00950. Piwi. 1 hit.
[Graphical view]
SUPFAMiSSF101690. SSF101690. 1 hit.
SSF53098. SSF53098. 1 hit.
PROSITEiPS50822. PIWI. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O67434-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGKEALLNLY RIEYRPKDTT FTVFKPTHEI QKEKLNKVRW RVFLQTGLPT
60 70 80 90 100
FRREDEFWCA GKVEKDTLYL TLSNGEIVEL KRVGEEEFRG FQNERECQEL
110 120 130 140 150
FRDFLTKTKV KDKFISDFYK KFRDKITVQG KNRKIALIPE VNEKVLKSEE
160 170 180 190 200
GYFLLHLDLK FRIQPFETLQ TLLERNDFNP KRIRVKPIGI DFVGRVQDVF
210 220 230 240 250
KAKEKGEEFF RLCMERSTHK SSKKAWEELL KNRELREKAF LVVLEKGYTY
260 270 280 290 300
PATILKPVLT YENLEDEERN EVADIVRMEP GKRLNLIRYI LRRYVKALRD
310 320 330 340 350
YGWYISPEEE RAKGKLNFKD TVLDAKGKNT KVITNLRKFL ELCRPFVKKD
360 370 380 390 400
VLSVEIISVS VYKKLEWRKE EFLKELINFL KNKGIKLKIK GKSLILAQTR
410 420 430 440 450
EEAKEKLIPV INKIKDVDLV IVFLEEYPKV DPYKSFLLYD FVKRELLKKM
460 470 480 490 500
IPSQVILNRT LKNENLKFVL LNVAEQVLAK TGNIPYKLKE IEGKVDAFVG
510 520 530 540 550
IDISRITRDG KTVNAVAFTK IFNSKGELVR YYLTSYPAFG EKLTEKAIGD
560 570 580 590 600
VFSLLEKLGF KKGSKIVVHR DGRLYRDEVA AFKKYGELYG YSLELLEIIK
610 620 630 640 650
RNNPRFFSNE KFIKGYFYKL SEDSVILATY NQVYEGTHQP IKVRKVYGEL
660 670 680 690 700
PVEVLCSQIL SLTLMNYSSF QPIKLPATVH YSDKITKLML RGIEPIKKEG

DIMYWL
Length:706
Mass (Da):83,122
Last modified:August 1, 1998 - v1
Checksum:i6211641D88BA850D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000657 Genomic DNA. Translation: AAC07406.1.
PIRiH70425.
RefSeqiNP_213999.1. NC_000918.1.
WP_010880937.1. NC_000918.1.

Genome annotation databases

EnsemblBacteriaiAAC07406; AAC07406; aq_1447.
GeneIDi1192965.
KEGGiaae:aq_1447.
PATRICi20960030. VBIAquAeo85532_1129.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000657 Genomic DNA. Translation: AAC07406.1.
PIRiH70425.
RefSeqiNP_213999.1. NC_000918.1.
WP_010880937.1. NC_000918.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1YVUX-ray2.90A1-706[»]
2F8SX-ray3.00A/B1-706[»]
2F8TX-ray3.10A/B1-706[»]
2NUBX-ray3.20A1-706[»]
ProteinModelPortaliO67434.
SMRiO67434. Positions 3-706.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

DIPiDIP-29161N.
STRINGi224324.aq_1447.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC07406; AAC07406; aq_1447.
GeneIDi1192965.
KEGGiaae:aq_1447.
PATRICi20960030. VBIAquAeo85532_1129.

Phylogenomic databases

eggNOGiENOG4108X5X. Bacteria.
COG1431. LUCA.
InParanoidiO67434.
KOiK07578.
OrthoDBiEOG6DG2QH.

Enzyme and pathway databases

BioCyciAAEO224324:GJBH-1040-MONOMER.

Miscellaneous databases

EvolutionaryTraceiO67434.

Family and domain databases

Gene3Di3.30.420.10. 1 hit.
InterProiIPR003100. PAZ_dom.
IPR003165. Piwi.
IPR012337. RNaseH-like_dom.
[Graphical view]
PfamiPF02171. Piwi. 1 hit.
[Graphical view]
SMARTiSM00950. Piwi. 1 hit.
[Graphical view]
SUPFAMiSSF101690. SSF101690. 1 hit.
SSF53098. SSF53098. 1 hit.
PROSITEiPS50822. PIWI. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: VF5Imported.
  2. "Crystal structure of A. aeolicus argonaute, a site-specific DNA-guided endoribonuclease, provides insights into RISC-mediated mRNA cleavage."
    Yuan Y.R., Pei Y., Ma J.B., Kuryavyi V., Zhadina M., Meister G., Chen H.Y., Dauter Z., Tuschl T., Patel D.J.
    Mol. Cell 19:405-419(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.90 ANGSTROMS) IN COMPLEX WITH CALCIUM.
  3. "A potential protein-RNA recognition event along the RISC-loading pathway from the structure of A. aeolicus Argonaute with externally bound siRNA."
    Yuan Y.R., Pei Y., Chen H.Y., Tuschl T., Patel D.J.
    Structure 14:1557-1565(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (3.00 ANGSTROMS).
  4. "Structure of Aquifex aeolicus argonaute highlights conformational flexibility of the PAZ domain as a potential regulator of RNA-induced silencing complex function."
    Rashid U.J., Paterok D., Koglin A., Gohlke H., Piehler J., Chen J.C.
    J. Biol. Chem. 282:13824-13832(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (3.20 ANGSTROMS).

Entry informationi

Entry nameiO67434_AQUAE
AccessioniPrimary (citable) accession number: O67434
Entry historyi
Integrated into UniProtKB/TrEMBL: August 1, 1998
Last sequence update: August 1, 1998
Last modified: March 16, 2016
This is version 93 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.