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Protein
Submitted name:

Cation transporting ATPase (E1-E2 family)

Gene

ctrA2

Organism
Aquifex aeolicus (strain VF5)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi12PROSITE-ProRule annotation1
Metal bindingi15PROSITE-ProRule annotation1

GO - Molecular functioni

Keywordsi

Molecular functionHydrolaseUniRule annotation
LigandMetal-bindingPROSITE-ProRule annotation

Enzyme and pathway databases

BioCyciAAEO224324:G1G15-1031-MONOMER
BRENDAi3.6.3.4 396

Protein family/group databases

TCDBi3.A.3.5.21 the p-type atpase (p-atpase) superfamily

Names & Taxonomyi

Protein namesi
Submitted name:
Cation transporting ATPase (E1-E2 family)Imported
Gene namesi
Name:ctrA2Imported
Ordered Locus Names:aq_1445Imported
OrganismiAquifex aeolicus (strain VF5)Imported
Taxonomic identifieri224324 [NCBI]
Taxonomic lineageiBacteriaAquificaeAquificalesAquificaceaeAquifex
Proteomesi
  • UP000000798 Componenti: Chromosome

Subcellular locationi

  • Cell membrane UniRule annotation

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei75 – 95HelicalUniRule annotationAdd BLAST21
Transmembranei311 – 332HelicalUniRule annotationAdd BLAST22
Transmembranei344 – 369HelicalUniRule annotationAdd BLAST26
Transmembranei628 – 647HelicalUniRule annotationAdd BLAST20
Transmembranei659 – 677HelicalUniRule annotationAdd BLAST19

GO - Cellular componenti

Keywords - Cellular componenti

Membrane

Interactioni

Protein-protein interaction databases

STRINGi224324.aq_1445

Structurei

3D structure databases

ProteinModelPortaliO67432
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini2 – 68HMAInterPro annotationAdd BLAST67

Sequence similaritiesi

Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily. [View classification]UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotation

Phylogenomic databases

eggNOGiENOG4105C59 Bacteria
COG2217 LUCA
HOGENOMiHOG000250397
InParanoidiO67432
KOiK01533
OMAiLFLYPTY
OrthoDBiPOG091H00YH

Family and domain databases

CDDicd00371 HMA, 1 hit
Gene3Di3.40.1110.10, 1 hit
3.40.50.1000, 2 hits
InterProiView protein in InterPro
IPR023299 ATPase_P-typ_cyto_dom_N
IPR018303 ATPase_P-typ_P_site
IPR023298 ATPase_P-typ_TM_dom_sf
IPR008250 ATPase_P-typ_transduc_dom_A_sf
IPR036412 HAD-like_sf
IPR023214 HAD_sf
IPR017969 Heavy-metal-associated_CS
IPR006121 HMA_dom
IPR036163 HMA_dom_sf
IPR027256 P-typ_ATPase_IB
IPR001757 P_typ_ATPase
PfamiView protein in Pfam
PF00403 HMA, 1 hit
SUPFAMiSSF55008 SSF55008, 1 hit
SSF56784 SSF56784, 3 hits
SSF81653 SSF81653, 1 hit
SSF81660 SSF81660, 1 hit
SSF81665 SSF81665, 3 hits
TIGRFAMsiTIGR01525 ATPase-IB_hvy, 1 hit
TIGR01494 ATPase_P-type, 1 hit
PROSITEiView protein in PROSITE
PS00154 ATPASE_E1_E2, 1 hit
PS01047 HMA_1, 1 hit
PS50846 HMA_2, 1 hit

Sequencei

Sequence statusi: Complete.

O67432-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRKAFKVYGM SCVNCARAIE ITLKRTEGVK NVNVSFELGR VEVEFDEDLI
60 70 80 90 100
SEEEIVKKIE ELGYSVERKK DYDKLFLGLG VLSSLFFLVG MFFTFPLKYE
110 120 130 140 150
LQFLLSSIVQ FTAGWKFYRG AYSSLKKGIG SMDTLVALGT TGAYVYSVLS
160 170 180 190 200
YFNLINSTPF FETNVFLITF VRLGKFIEEK AKERAVKGLK ELVNLSFRKV
210 220 230 240 250
KVLEGEKEVE KNVREVFKGE KVVYRSGEQI LLDGVIIKGE GLVNEAVITG
260 270 280 290 300
EPVPILKKEG DEVYSGSVLE KGYIITKVTK TFESSFINTM KKLVEESLKE
310 320 330 340 350
KPKIQRISDK VSHYFVLFVV ILSVITFLTW FIKTGEINRA VQFSLAVLVV
360 370 380 390 400
SCPCAFGIAV PLAVSVGIYK AVKRGILPKK GTIFEVAPKV DTVIFDKTGT
410 420 430 440 450
LTEGKLKVKE INVPEKYFDV LYSMENYSNH PVAKAVREYL KPYVKREAKL
460 470 480 490 500
EGCEEILGVG VRCGEFIAGK AELWGKNSQN GVIRVGFGTK DKLIGEIILE
510 520 530 540 550
DSVRKEAKEV VEFLKGKGIN VILLTGDTKE NAQRIAKELG IKEVIANVKP
560 570 580 590 600
EEKLKVVKEL QEKGRKVCMV GDGVNDAPAL AQSDLGIAVA EGTDLAKLSG
610 620 630 640 650
DVVIHKLSSL PQVFTLSERV YRKIKENFFW AFAYNVTFIP IAAGVLWSKG
660 670
IYLKPEFAGL LMALSSVSVV LNTLRLLKD
Length:679
Mass (Da):75,717
Last modified:August 1, 1998 - v1
Checksum:iCE5A3ABBD95E1CDE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000657 Genomic DNA Translation: AAC07388.1
PIRiF70425
RefSeqiNP_213997.1, NC_000918.1
WP_010880935.1, NC_000918.1

Genome annotation databases

EnsemblBacteriaiAAC07388; AAC07388; aq_1445
GeneIDi1192963
KEGGiaae:aq_1445

Entry informationi

Entry nameiO67432_AQUAE
AccessioniPrimary (citable) accession number: O67432
Entry historyiIntegrated into UniProtKB/TrEMBL: August 1, 1998
Last sequence update: August 1, 1998
Last modified: April 25, 2018
This is version 146 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health