O67325 (O67325_AQUAE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
ATP-dependent Clp protease EMBL AAC07290.1

Gene names

Name:	clpC EMBL AAC07290.1
Ordered Locus Names:	aq_1296 EMBL AAC07290.1

Organism

Aquifex aeolicus (strain VF5) [Reference proteome] [HAMAP] EMBL AAC07290.1

Taxonomic identifier

224324 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Aquificae › Aquificae › Aquificales › Aquificaceae › Aquifex › Aquifex aeolicus

Protein attributes

Sequence length	810 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the clpA/clpB family. RuleBase RU004432

Ontologies

Keywords
Ligand	ATP-binding RuleBase RU004433 Nucleotide-binding
Molecular function	Chaperone SAAS SAAS023150 RuleBase RU004433 Hydrolase Protease EMBL AAC07290.1
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	proteolysis Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW nucleoside-triphosphatase activity Inferred from electronic annotation. Source: InterPro peptidase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	O67325 [UniParc]. Last modified August 1, 1998. Version 1. Checksum: 5DC9A95904AA38E7	FASTA	810	92,356
	10 20 30 40 50 60 MFEKFTERAR QVILRAREEA LELGHSYLGS EHILLALIKD EDIPVLVLSK LGVSPEKIRK 70 80 90 100 110 120 AIMGQITKGS HSGEVLFAPD AKRVIEFAVE EARILHHQFV GPEHLLIGVV REKTGLGGRI 130 140 150 160 170 180 LRSFGLDEYS VRREVLQLLG ELPPQESQRY VSTPNLDRFS RDLTQMAREG KLDPVIGREK 190 200 210 220 230 240 EIERVIQILV RRRKNNPVLL GDPGVGKTAI VEGLAQRIAN KEVPEPLLNK RVVALDLAAL 250 260 270 280 290 300 VAGTKYRGQF EERLKNILKE LEKANNVILF IDELHTLVGA GSAEGSIDAS NMLKPALARG 310 320 330 340 350 360 EIQVIGATTV DEYRKYIEKD GALERRFQPV YVEQPSPEDT IQILYGLKPK FEEFHKVEYT 370 380 390 400 410 420 PEAIEKAVEL SVKYITDRNL PDKAIDVMDE AGALVKLKAT QLPPELKEIE EKIKELEKEK 430 440 450 460 470 480 EKAVKEQDYE KAAKIRDEEL RLRAKFETMK AKWKEEMEKN RPKVTDEDVA EVVARWTGVP 490 500 510 520 530 540 VKRVHESDAE KLLHIEEELK KRVVGQDEAI KAVAKAIRRS RVGLKGKHRP IGVFMFLGPT 550 560 570 580 590 600 GVGKTETAKA LAEYLFGTED ALIRFDMSEY MEKHTVSRLI GAPPGYVGYE EGGQLTEAVR 610 620 630 640 650 660 RRPYSVLLFD EIEKAHPDVF NIFLQIFDDG RLTDGLGRTV DFSNTIIIMT SNLGARLITG 670 680 690 700 710 720 GTMGFEKKQG LLNFEEMRKN VLDQVKRTFS PEFLNRLDEI IVFRPLEKKD IEQILELQLK 730 740 750 760 770 780 EINEKLKDWN VRVKLHKSFV NWIIEKEYKP EFGARSLKRA LQRHVEDLLA EELIKGTLKG 790 800 810 VEEVEIRVRN DKPYLKPVKK KEKVEALLEK

References

[1]

"The complete genome of the hyperthermophilic bacterium Aquifex aeolicus." Deckert G., Warren P.V., Gaasterland T., Young W.G., Lenox A.L., Graham D.E., Overbeek R., Snead M.A., Keller M., Aujay M., Huber R., Feldman R.A., Short J.M., Olsen G.J., Swanson R.V. Nature 392:353-358(1998) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: VF5 EMBL AAC07290.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE000657 Genomic DNA. Translation: AAC07290.1.
PIR	B70412.
RefSeq	NP_213889.1. NC_000918.1.
3D structure databases
HSSP	HSSP built from PDB template 1JBK based on UniProtKB P03815.
ProteinModelPortal	O67325.
SMR	O67325. Positions 156-344.
ModBase	Search...
Protein-protein interaction databases
STRING	224324.aq_1296.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAC07290; AAC07290; aq_1296.
GeneID	1192763.
KEGG	aae:aq_1296.
PATRIC	20959792. VBIAquAeo85532_1013.
Phylogenomic databases
HOGENOM	HOG000218210.
KO	K03696.
OMA	YLGSEHI.
ProtClustDB	CLSK2299650.
Enzyme and pathway databases
BioCyc	AAEO224324:GJBH-927-MONOMER.
Family and domain databases
Gene3D	1.10.1780.10. 1 hit. 4.10.860.10. 1 hit.
InterPro	IPR003593. AAA+_ATPase. IPR013093. ATPase_AAA-2. IPR003959. ATPase_AAA_core. IPR018368. Chaperonin_ClpA/B_CS. IPR001270. Chaprnin_ClpA/B. IPR019489. Clp_ATPase_C. IPR004176. Clp_N. IPR023150. Dbl_Clp-N. IPR001943. UVR_dom. [Graphical view]
Pfam	PF00004. AAA. 1 hit. PF07724. AAA_2. 1 hit. PF02861. Clp_N. 2 hits. PF10431. ClpB_D2-small. 1 hit. PF02151. UVR. 1 hit. [Graphical view]
PRINTS	PR00300. CLPPROTEASEA.
SMART	SM00382. AAA. 2 hits. SM01086. ClpB_D2-small. 1 hit. [Graphical view]
PROSITE	PS00870. CLPAB_1. 1 hit. PS00871. CLPAB_2. 1 hit. PS50151. UVR. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

O67325_AQUAE

Accession

Primary (citable) accession number: O67325

Entry history

Integrated into UniProtKB/TrEMBL:	August 1, 1998
Last sequence update:	August 1, 1998
Last modified:	May 1, 2013
This is version 81 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)