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Protein

Sec-independent protein translocase protein TatC

Gene

tatC

Organism
Aquifex aeolicus (strain VF5)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.UniRule annotation

GO - Molecular functioni

  1. protein transmembrane transporter activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. protein transport by the Tat complex Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Biological processi

Protein transport, Translocation, Transport

Enzyme and pathway databases

BioCyciAAEO224324:GJBH-906-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Sec-independent protein translocase protein TatCUniRule annotation
Gene namesi
Name:tatCUniRule annotation
Ordered Locus Names:aq_1267
OrganismiAquifex aeolicus (strain VF5)
Taxonomic identifieri224324 [NCBI]
Taxonomic lineageiBacteriaAquificaeAquificalesAquificaceaeAquifex
ProteomesiUP000000798: Chromosome

Subcellular locationi

Cell inner membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei15 – 3521HelicalUniRule annotationAdd
BLAST
Transmembranei61 – 8121HelicalUniRule annotationAdd
BLAST
Transmembranei103 – 12321HelicalUniRule annotationAdd
BLAST
Transmembranei152 – 17221HelicalUniRule annotationAdd
BLAST
Transmembranei191 – 21121HelicalUniRule annotationAdd
BLAST
Transmembranei212 – 23221HelicalUniRule annotationAdd
BLAST

GO - Cellular componenti

  1. integral component of plasma membrane Source: UniProtKB-HAMAP
  2. TAT protein transport complex Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 240240Sec-independent protein translocase protein TatCPRO_0000098093Add
BLAST

Interactioni

Subunit structurei

Forms a complex with TatA.UniRule annotation

Protein-protein interaction databases

STRINGi224324.aq_1267.

Structurei

Secondary structure

1
240
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Helixi6 – 3025Combined sources
Helixi32 – 4615Combined sources
Beta strandi56 – 583Combined sources
Helixi60 – 8829Combined sources
Turni89 – 924Combined sources
Turni97 – 1004Combined sources
Helixi101 – 12020Combined sources
Helixi122 – 1287Combined sources
Turni129 – 1313Combined sources
Beta strandi133 – 1353Combined sources
Beta strandi138 – 1414Combined sources
Helixi146 – 16318Combined sources
Helixi166 – 17510Combined sources
Helixi181 – 20222Combined sources
Helixi206 – 22520Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4B4AX-ray3.50A1-240[»]
4HTSX-ray4.00A1-232[»]
4HTTX-ray6.80A/B1-235[»]
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the TatC family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG0805.
HOGENOMiHOG000245380.
InParanoidiO67305.
KOiK03118.
OMAiATQIYKF.
OrthoDBiEOG60SCQS.

Family and domain databases

HAMAPiMF_00902. TatC.
InterProiIPR019820. Sec-indep_translocase_CS.
IPR002033. TatC.
[Graphical view]
PANTHERiPTHR30371:SF0. PTHR30371:SF0. 1 hit.
PfamiPF00902. TatC. 1 hit.
[Graphical view]
PRINTSiPR01840. TATCFAMILY.
TIGRFAMsiTIGR00945. tatC. 1 hit.
PROSITEiPS01218. TATC. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O67305-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPLTEHLREL RYRLIISIIA FLIGSGIAFY FAKYVFEILK EPILKSYPEV
60 70 80 90 100
ELITLSPTEP LFILIKISLA VGFIIASPVI LYQFWRFIEP ALYSHEKRAF
110 120 130 140 150
IPLLLGSILL FMLGALFAYF IVLPLALKFL LGLGFTQLLA TPYLSVDMYI
160 170 180 190 200
SFVLKLVVAF GIAFEMPIVL YVLQKAGVIT PEQLASFRKY FIVIAFVIGA
210 220 230 240
IIAPDVSTQV LMAIPLLLLY EISIFLGKLA TRKKKEIQKA
Length:240
Mass (Da):27,129
Last modified:August 1, 1998 - v1
Checksum:iFC3125C54D5B9047
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000657 Genomic DNA. Translation: AAC07267.1.
PIRiF70409.
RefSeqiNP_213869.1. NC_000918.1.

Genome annotation databases

EnsemblBacteriaiAAC07267; AAC07267; aq_1267.
GeneIDi1192743.
KEGGiaae:aq_1267.
PATRICi20959740. VBIAquAeo85532_0988.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000657 Genomic DNA. Translation: AAC07267.1.
PIRiF70409.
RefSeqiNP_213869.1. NC_000918.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4B4AX-ray3.50A1-240[»]
4HTSX-ray4.00A1-232[»]
4HTTX-ray6.80A/B1-235[»]
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi224324.aq_1267.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC07267; AAC07267; aq_1267.
GeneIDi1192743.
KEGGiaae:aq_1267.
PATRICi20959740. VBIAquAeo85532_0988.

Phylogenomic databases

eggNOGiCOG0805.
HOGENOMiHOG000245380.
InParanoidiO67305.
KOiK03118.
OMAiATQIYKF.
OrthoDBiEOG60SCQS.

Enzyme and pathway databases

BioCyciAAEO224324:GJBH-906-MONOMER.

Family and domain databases

HAMAPiMF_00902. TatC.
InterProiIPR019820. Sec-indep_translocase_CS.
IPR002033. TatC.
[Graphical view]
PANTHERiPTHR30371:SF0. PTHR30371:SF0. 1 hit.
PfamiPF00902. TatC. 1 hit.
[Graphical view]
PRINTSiPR01840. TATCFAMILY.
TIGRFAMsiTIGR00945. tatC. 1 hit.
PROSITEiPS01218. TATC. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: VF5.

Entry informationi

Entry nameiTATC_AQUAE
AccessioniPrimary (citable) accession number: O67305
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: August 1, 1998
Last modified: February 4, 2015
This is version 95 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.