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O67305

- TATC_AQUAE

UniProt

O67305 - TATC_AQUAE

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Protein
Sec-independent protein translocase protein TatC
Gene
tatC, aq_1267
Organism
Aquifex aeolicus (strain VF5)
Status
Reviewed - Annotation score: 2 out of 5 - Experimental evidence at protein leveli

Functioni

Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes By similarity.UniRule annotation

GO - Molecular functioni

  1. protein transmembrane transporter activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. protein transport by the Tat complex Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Biological processi

Protein transport, Translocation, Transport

Enzyme and pathway databases

BioCyciAAEO224324:GJBH-906-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Sec-independent protein translocase protein TatC
Gene namesi
Name:tatC
Ordered Locus Names:aq_1267
OrganismiAquifex aeolicus (strain VF5)
Taxonomic identifieri224324 [NCBI]
Taxonomic lineageiBacteriaAquificaeAquificalesAquificaceaeAquifex
ProteomesiUP000000798: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei15 – 3521Helical; Reviewed prediction
Add
BLAST
Transmembranei61 – 8121Helical; Reviewed prediction
Add
BLAST
Transmembranei103 – 12321Helical; Reviewed prediction
Add
BLAST
Transmembranei152 – 17221Helical; Reviewed prediction
Add
BLAST
Transmembranei191 – 21121Helical; Reviewed prediction
Add
BLAST
Transmembranei212 – 23221Helical; Reviewed prediction
Add
BLAST

GO - Cellular componenti

  1. TAT protein transport complex Source: UniProtKB-HAMAP
  2. integral component of plasma membrane Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 240240Sec-independent protein translocase protein TatCUniRule annotation
PRO_0000098093Add
BLAST

Interactioni

Subunit structurei

Forms a complex with TatA By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi224324.aq_1267.

Structurei

Secondary structure

Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Helixi6 – 3025
Helixi32 – 4615
Beta strandi56 – 583
Helixi60 – 8829
Turni89 – 924
Turni97 – 1004
Helixi101 – 12020
Helixi122 – 1287
Turni129 – 1313
Beta strandi133 – 1353
Beta strandi138 – 1414
Helixi146 – 16318
Helixi166 – 17510
Helixi181 – 20222
Helixi206 – 22520

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4B4AX-ray3.50A1-240[»]
4HTSX-ray4.00A1-232[»]
4HTTX-ray6.80A/B1-235[»]

Family & Domainsi

Sequence similaritiesi

Belongs to the TatC family.

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG0805.
HOGENOMiHOG000245380.
KOiK03118.
OMAiVILHQIW.
OrthoDBiEOG60SCQS.

Family and domain databases

HAMAPiMF_00902. TatC.
InterProiIPR019820. Sec-indep_translocase_CS.
IPR002033. TatC.
[Graphical view]
PfamiPF00902. TatC. 1 hit.
[Graphical view]
PRINTSiPR01840. TATCFAMILY.
TIGRFAMsiTIGR00945. tatC. 1 hit.
PROSITEiPS01218. TATC. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O67305-1 [UniParc]FASTAAdd to Basket

« Hide

MPLTEHLREL RYRLIISIIA FLIGSGIAFY FAKYVFEILK EPILKSYPEV    50
ELITLSPTEP LFILIKISLA VGFIIASPVI LYQFWRFIEP ALYSHEKRAF 100
IPLLLGSILL FMLGALFAYF IVLPLALKFL LGLGFTQLLA TPYLSVDMYI 150
SFVLKLVVAF GIAFEMPIVL YVLQKAGVIT PEQLASFRKY FIVIAFVIGA 200
IIAPDVSTQV LMAIPLLLLY EISIFLGKLA TRKKKEIQKA 240
Length:240
Mass (Da):27,129
Last modified:August 1, 1998 - v1
Checksum:iFC3125C54D5B9047
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE000657 Genomic DNA. Translation: AAC07267.1.
PIRiF70409.
RefSeqiNP_213869.1. NC_000918.1.
WP_010880807.1. NC_000918.1.

Genome annotation databases

EnsemblBacteriaiAAC07267; AAC07267; aq_1267.
GeneIDi1192743.
KEGGiaae:aq_1267.
PATRICi20959740. VBIAquAeo85532_0988.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE000657 Genomic DNA. Translation: AAC07267.1 .
PIRi F70409.
RefSeqi NP_213869.1. NC_000918.1.
WP_010880807.1. NC_000918.1.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
4B4A X-ray 3.50 A 1-240 [» ]
4HTS X-ray 4.00 A 1-232 [» ]
4HTT X-ray 6.80 A/B 1-235 [» ]
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 224324.aq_1267.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAC07267 ; AAC07267 ; aq_1267 .
GeneIDi 1192743.
KEGGi aae:aq_1267.
PATRICi 20959740. VBIAquAeo85532_0988.

Phylogenomic databases

eggNOGi COG0805.
HOGENOMi HOG000245380.
KOi K03118.
OMAi VILHQIW.
OrthoDBi EOG60SCQS.

Enzyme and pathway databases

BioCyci AAEO224324:GJBH-906-MONOMER.

Family and domain databases

HAMAPi MF_00902. TatC.
InterProi IPR019820. Sec-indep_translocase_CS.
IPR002033. TatC.
[Graphical view ]
Pfami PF00902. TatC. 1 hit.
[Graphical view ]
PRINTSi PR01840. TATCFAMILY.
TIGRFAMsi TIGR00945. tatC. 1 hit.
PROSITEi PS01218. TATC. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: VF5.

Entry informationi

Entry nameiTATC_AQUAE
AccessioniPrimary (citable) accession number: O67305
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: August 1, 1998
Last modified: September 3, 2014
This is version 90 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi