Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

O67292

- CDSA_AQUAE

UniProt

O67292 - CDSA_AQUAE

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Phosphatidate cytidylyltransferase

Gene

cdsA

Organism
Aquifex aeolicus (strain VF5)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

CTP + phosphatidate = diphosphate + CDP-diacylglycerol.

Pathwayi

GO - Molecular functioni

  1. phosphatidate cytidylyltransferase activity Source: UniProtKB-EC

GO - Biological processi

  1. CDP-diacylglycerol biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Nucleotidyltransferase, Transferase

Keywords - Biological processi

Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism

Enzyme and pathway databases

BioCyciAAEO224324:GJBH-893-MONOMER.
UniPathwayiUPA00557; UER00614.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphatidate cytidylyltransferase (EC:2.7.7.41)
Alternative name(s):
CDP-DAG synthase
CDP-DG synthase
CDP-diacylglycerol synthase
Short name:
CDS
CDP-diglyceride pyrophosphorylase
CDP-diglyceride synthase
CTP:phosphatidate cytidylyltransferase
Gene namesi
Name:cdsA
Synonyms:cds
Ordered Locus Names:aq_1249
OrganismiAquifex aeolicus (strain VF5)
Taxonomic identifieri224324 [NCBI]
Taxonomic lineageiBacteriaAquificaeAquificalesAquificaceaeAquifex
ProteomesiUP000000798: Chromosome

Subcellular locationi

Cell membrane By similarity; Multi-pass membrane protein By similarity

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 259259Phosphatidate cytidylyltransferasePRO_0000090725Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi224324.aq_1249.

Structurei

Transmembrane

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei31 – 5121HelicalSequence AnalysisAdd
BLAST
Transmembranei69 – 8921HelicalSequence AnalysisAdd
BLAST
Transmembranei103 – 12321HelicalSequence AnalysisAdd
BLAST
Transmembranei129 – 14921HelicalSequence AnalysisAdd
BLAST
Transmembranei170 – 19021HelicalSequence AnalysisAdd
BLAST
Transmembranei193 – 21321HelicalSequence AnalysisAdd
BLAST
Transmembranei236 – 25621HelicalSequence AnalysisAdd
BLAST

Family & Domainsi

Sequence similaritiesi

Belongs to the CDS family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG0575.
HOGENOMiHOG000006169.
InParanoidiO67292.
KOiK00981.
OMAiFLMNIYL.
OrthoDBiEOG6TBHJT.

Family and domain databases

InterProiIPR000374. PC_trans.
[Graphical view]
PfamiPF01148. CTP_transf_1. 1 hit.
[Graphical view]
PROSITEiPS01315. CDS. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O67292-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MRITQGERES SGEFLMSREF YGVLIGVTTL LVIFLPKSLF LLVILFLCFA
60 70 80 90 100
ISREVSVALG ENEVFYFSPL VLLTYYFADP LVFPLIGLLS LYFAYKRWEL
110 120 130 140 150
NSFFKSTFLL FYPALFLVYL IKIKEISTYY LLIFIFGIWI NDVFAYYIGK
160 170 180 190 200
NFGKTPLFPK ISPKKTVEGF LGGVLFGSLF FALTLPYGIL NSFLLGTFVL
210 220 230 240 250
TVGVAGDYFK SFIKRQVGIK DFSNVFGEHG GFTDRFDALV FSAPVFYLIM

CAGELNCKL
Length:259
Mass (Da):29,486
Last modified:August 1, 1998 - v1
Checksum:iD5FB386647BD0D0E
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE000657 Genomic DNA. Translation: AAC07246.1.
PIRiA70408.
RefSeqiNP_213856.1. NC_000918.1.
WP_010880794.1. NC_000918.1.

Genome annotation databases

EnsemblBacteriaiAAC07246; AAC07246; aq_1249.
GeneIDi1192730.
KEGGiaae:aq_1249.
PATRICi20959710. VBIAquAeo85532_0973.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE000657 Genomic DNA. Translation: AAC07246.1 .
PIRi A70408.
RefSeqi NP_213856.1. NC_000918.1.
WP_010880794.1. NC_000918.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 224324.aq_1249.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAC07246 ; AAC07246 ; aq_1249 .
GeneIDi 1192730.
KEGGi aae:aq_1249.
PATRICi 20959710. VBIAquAeo85532_0973.

Phylogenomic databases

eggNOGi COG0575.
HOGENOMi HOG000006169.
InParanoidi O67292.
KOi K00981.
OMAi FLMNIYL.
OrthoDBi EOG6TBHJT.

Enzyme and pathway databases

UniPathwayi UPA00557 ; UER00614 .
BioCyci AAEO224324:GJBH-893-MONOMER.

Family and domain databases

InterProi IPR000374. PC_trans.
[Graphical view ]
Pfami PF01148. CTP_transf_1. 1 hit.
[Graphical view ]
PROSITEi PS01315. CDS. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: VF5.

Entry informationi

Entry nameiCDSA_AQUAE
AccessioniPrimary (citable) accession number: O67292
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: August 1, 1998
Last modified: October 29, 2014
This is version 93 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3