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Protein

Flagellar biosynthesis protein FlhA

Gene

flhA

Organism
Aquifex aeolicus (strain VF5)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin (By similarity).By similarity

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Bacterial flagellum biogenesis, Bacterial flagellum protein export, Protein transport, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Flagellar biosynthesis protein FlhA
Gene namesi
Name:flhA
Ordered Locus Names:aq_1212
OrganismiAquifex aeolicus (strain VF5)
Taxonomic identifieri224324 [NCBI]
Taxonomic lineageiBacteriaAquificaeAquificalesAquificaceaeAquifex
Proteomesi
  • UP000000798 Componenti: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei8 – 28HelicalSequence analysisAdd BLAST21
Transmembranei29 – 49HelicalSequence analysisAdd BLAST21
Transmembranei57 – 77HelicalSequence analysisAdd BLAST21
Transmembranei105 – 125HelicalSequence analysisAdd BLAST21
Transmembranei194 – 214HelicalSequence analysisAdd BLAST21
Transmembranei231 – 251HelicalSequence analysisAdd BLAST21
Transmembranei275 – 295HelicalSequence analysisAdd BLAST21
Transmembranei340 – 360HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001900091 – 678Flagellar biosynthesis protein FlhAAdd BLAST678

Interactioni

Protein-protein interaction databases

STRINGi224324.aq_1212.

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105D7B. Bacteria.
COG1298. LUCA.
HOGENOMiHOG000254014.
InParanoidiO67265.
KOiK02400.
OMAiETKELGW.
OrthoDBiPOG091H0483.

Family and domain databases

InterProiIPR025505. FHIPEP_CS.
IPR006301. FlhA.
IPR001712. T3SS_FHIPEP.
[Graphical view]
PfamiPF00771. FHIPEP. 1 hit.
[Graphical view]
PIRSFiPIRSF005419. FlhA. 1 hit.
PRINTSiPR00949. TYPE3IMAPROT.
TIGRFAMsiTIGR01398. FlhA. 1 hit.
PROSITEiPS00994. FHIPEP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O67265-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRGKEFWIIL AVVLILSAII IPIPALLLDL LLTLSITFSL TVLLLTFFIK
60 70 80 90 100
NPLEFSSFPS VLLLGTLLRL SLNIAAARRI LLHGHEGTHA AGKVIEAFGK
110 120 130 140 150
LVAGGDVVVG LIVFLIFIVI NFIVITKGAE RISEVAARFT LDALPGKQMS
160 170 180 190 200
IDADLNAGLI TEEEAKRRRQ ELEKEANFYA AMDGASKFIR GDAIAALIIL
210 220 230 240 250
FLSLVGGLLI GIGIRGMDLA SAVKTYTILS IGEGLASQVP ALLLSTAAGV
260 270 280 290 300
LTTKMSSREN LGEAISEELT KQPRALLFSA GVLGFIGLIP GLPTLPFLAM
310 320 330 340 350
SAILAGAYYL VQQSLKEREL KELEKLAQEK TKEKEEEGEE LIPQPEPITL
360 370 380 390 400
EIGYALIPLV DESQGGQIPK KIKNLRKQIA KEYGVIVPLI HIRDNLRLKP
410 420 430 440 450
NEYRILIKGI EIDRYELMPG HYLAVNLGNA KGPIEGIETY DPAFKIKAYW
460 470 480 490 500
ITEDKKEEAQ KLGYMVVDAE TVLITHLSEV IKRNLHELLT RNEVMELIEM
510 520 530 540 550
LSKKYPKVVK EIVPEQVPIS IIHRVLQNLL REGIPVNDLL TILETLADYI
560 570 580 590 600
EQTKDPDLLT EYVRQALSKR ITRMYLTNGT LYAIALSPKV EAKLVKFLKE
610 620 630 640 650
NREDEFIDYV LNTLLPKIKN EIVKFAQYGA VPVLLTSGEV RRFVRKTIEP
660 670
YLSELAVLSY NELEKQVNIK IIGIVDED
Length:678
Mass (Da):75,392
Last modified:August 1, 1998 - v1
Checksum:i9C987330D32CA47D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000657 Genomic DNA. Translation: AAC07227.1.
PIRiF70404.
RefSeqiNP_213829.1. NC_000918.1.
WP_010880767.1. NC_000918.1.

Genome annotation databases

EnsemblBacteriaiAAC07227; AAC07227; aq_1212.
GeneIDi1192611.
KEGGiaae:aq_1212.
PATRICi20959648. VBIAquAeo85532_0943.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000657 Genomic DNA. Translation: AAC07227.1.
PIRiF70404.
RefSeqiNP_213829.1. NC_000918.1.
WP_010880767.1. NC_000918.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi224324.aq_1212.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC07227; AAC07227; aq_1212.
GeneIDi1192611.
KEGGiaae:aq_1212.
PATRICi20959648. VBIAquAeo85532_0943.

Phylogenomic databases

eggNOGiENOG4105D7B. Bacteria.
COG1298. LUCA.
HOGENOMiHOG000254014.
InParanoidiO67265.
KOiK02400.
OMAiETKELGW.
OrthoDBiPOG091H0483.

Family and domain databases

InterProiIPR025505. FHIPEP_CS.
IPR006301. FlhA.
IPR001712. T3SS_FHIPEP.
[Graphical view]
PfamiPF00771. FHIPEP. 1 hit.
[Graphical view]
PIRSFiPIRSF005419. FlhA. 1 hit.
PRINTSiPR00949. TYPE3IMAPROT.
TIGRFAMsiTIGR01398. FlhA. 1 hit.
PROSITEiPS00994. FHIPEP. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiFLHA_AQUAE
AccessioniPrimary (citable) accession number: O67265
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: August 1, 1998
Last modified: November 2, 2016
This is version 96 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.