Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Histidine kinase sensor protein

Gene

hksP1

Organism
Aquifex aeolicus (strain VF5)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

Catalytic activityi

ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.SAAS annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

KinaseSAAS annotationImported, Transferase

Keywords - Ligandi

ATP-bindingSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciAAEO224324:GJBH-796-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Histidine kinase sensor proteinImported
Gene namesi
Name:hksP1Imported
Ordered Locus Names:aq_1115Imported
OrganismiAquifex aeolicus (strain VF5)Imported
Taxonomic identifieri224324 [NCBI]
Taxonomic lineageiBacteriaAquificaeAquificalesAquificaceaeAquifex
Proteomesi
  • UP000000798 Componenti: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei6 – 2722HelicalSequence analysisAdd
BLAST
Transmembranei249 – 27224HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Interactioni

Protein-protein interaction databases

STRINGi224324.aq_1115.

Structurei

3D structure databases

ProteinModelPortaliO67197.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini317 – 36852PAS (PER-ARNT-SIM)InterPro annotationAdd
BLAST
Domaini439 – 639201Histidine kinaseInterPro annotationAdd
BLAST

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG4105BZU. Bacteria.
COG0642. LUCA.
COG2202. LUCA.
HOGENOMiHOG000115054.
InParanoidiO67197.
KOiK02482.
OMAiKRFVEDM.
OrthoDBiPOG091H053D.

Family and domain databases

Gene3Di1.10.287.130. 1 hit.
3.30.565.10. 1 hit.
InterProiIPR003594. HATPase_C.
IPR005467. His_kinase_dom.
IPR003661. HisK_dim/P.
IPR000014. PAS.
IPR013767. PAS_fold.
IPR004358. Sig_transdc_His_kin-like_C.
[Graphical view]
PfamiPF02518. HATPase_c. 1 hit.
PF00512. HisKA. 1 hit.
PF00989. PAS. 1 hit.
[Graphical view]
PRINTSiPR00344. BCTRLSENSOR.
SMARTiSM00387. HATPase_c. 1 hit.
SM00388. HisKA. 1 hit.
SM00091. PAS. 1 hit.
[Graphical view]
SUPFAMiSSF47384. SSF47384. 1 hit.
SSF55785. SSF55785. 1 hit.
SSF55874. SSF55874. 1 hit.
TIGRFAMsiTIGR00229. sensory_box. 1 hit.
PROSITEiPS50109. HIS_KIN. 1 hit.
PS50112. PAS. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O67197-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTLKTKIILL VILLTALPAL LSLLHYYSMK RELIQKALER NREIVEKLAD
60 70 80 90 100
RVDMYISETL HSIASKVNQY KGYGLNEREI IWKITGEVYG VFEGAFYSPE
110 120 130 140 150
GKLITSASRE KVNPNFPERI SPEGRSKLLY TPYLEPYVRV LYKDEEFGIT
160 170 180 190 200
FGYYIFSLDL SAFWNRLVNR YKGLEAFLLD ENSRLIAFPD TRFYDGRKIP
210 220 230 240 250
LREGIYRSDF LGTDVIGTFA KSKGGKWIVY AEEPLIYVLS PLENYRKEVI
260 270 280 290 300
LAGLFTSFSG GILCLIIIIR IFKPLENFKD YVVSWAKENL SENLKLKDDV
310 320 330 340 350
EIFLKTFRSL IKKVEEEKKI YEAFFKNSFD GVVLFDTSLK VSNVNENFCE
360 370 380 390 400
IFQVKKDEVI GKSMEDLIGE RLPLKNTFIR EVELKLGKKH YCSLRQGILI
410 420 430 440 450
IEDVPYVVWW LKDLSKEKEL RGMLERTSKL AVAGEIACSL AHQLNTPLAS
460 470 480 490 500
IMGYAELLNL SEKDQRTKEK LDLIIKQAHR CKEIIGKMLY LGKVDSRPAY
510 520 530 540 550
VNLEELILEV LEILEPKARK KGVNVRFENG DAGKIFGFPW QIEQILINIL
560 570 580 590 600
DNAIDALPEG ESIYIKLKKE EEYVVLEVKD KGKGFEDPEK AFEPFYTTKQ
610 620 630 640
NGTGLGLSIV KTFVEGMNGK IEVKNCSGAL VKVYLPEVAE SERFGN
Length:646
Mass (Da):74,185
Last modified:August 1, 1998 - v1
Checksum:i2643E4238EF30DC5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000657 Genomic DNA. Translation: AAC07158.1.
PIRiB70396.
RefSeqiNP_213761.1. NC_000918.1.
WP_010880699.1. NC_000918.1.

Genome annotation databases

EnsemblBacteriaiAAC07158; AAC07158; aq_1115.
GeneIDi1192543.
KEGGiaae:aq_1115.
PATRICi20959502. VBIAquAeo85532_0871.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000657 Genomic DNA. Translation: AAC07158.1.
PIRiB70396.
RefSeqiNP_213761.1. NC_000918.1.
WP_010880699.1. NC_000918.1.

3D structure databases

ProteinModelPortaliO67197.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi224324.aq_1115.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC07158; AAC07158; aq_1115.
GeneIDi1192543.
KEGGiaae:aq_1115.
PATRICi20959502. VBIAquAeo85532_0871.

Phylogenomic databases

eggNOGiENOG4105BZU. Bacteria.
COG0642. LUCA.
COG2202. LUCA.
HOGENOMiHOG000115054.
InParanoidiO67197.
KOiK02482.
OMAiKRFVEDM.
OrthoDBiPOG091H053D.

Enzyme and pathway databases

BioCyciAAEO224324:GJBH-796-MONOMER.

Family and domain databases

Gene3Di1.10.287.130. 1 hit.
3.30.565.10. 1 hit.
InterProiIPR003594. HATPase_C.
IPR005467. His_kinase_dom.
IPR003661. HisK_dim/P.
IPR000014. PAS.
IPR013767. PAS_fold.
IPR004358. Sig_transdc_His_kin-like_C.
[Graphical view]
PfamiPF02518. HATPase_c. 1 hit.
PF00512. HisKA. 1 hit.
PF00989. PAS. 1 hit.
[Graphical view]
PRINTSiPR00344. BCTRLSENSOR.
SMARTiSM00387. HATPase_c. 1 hit.
SM00388. HisKA. 1 hit.
SM00091. PAS. 1 hit.
[Graphical view]
SUPFAMiSSF47384. SSF47384. 1 hit.
SSF55785. SSF55785. 1 hit.
SSF55874. SSF55874. 1 hit.
TIGRFAMsiTIGR00229. sensory_box. 1 hit.
PROSITEiPS50109. HIS_KIN. 1 hit.
PS50112. PAS. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiO67197_AQUAE
AccessioniPrimary (citable) accession number: O67197
Entry historyi
Integrated into UniProtKB/TrEMBL: August 1, 1998
Last sequence update: August 1, 1998
Last modified: September 7, 2016
This is version 124 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.