O67146 (O67146_AQUAE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Formate dehydrogenase alpha subunit EMBL AAC07107.1

Gene names

Name:	fdoG EMBL AAC07107.1
Ordered Locus Names:	aq_1039

Organism

Aquifex aeolicus (strain VF5)

Taxonomic identifier

224324 [NCBI]

Taxonomic lineage

Bacteria › Aquificae › Aquificales › Aquificaceae › Aquifex

Protein attributes

Sequence length	1015 AA.
Sequence status	Complete.
Protein existence	Predicted

Ontologies

Keywords
Coding sequence diversity	Selenocysteine EMBL AAC07107.1
Ligand	4Fe-4S SAAS SAAS006311 Iron Iron-sulfur Metal-binding Molybdenum SAAS SAAS006311 Selenium EMBL AAC07107.1
Molecular function	Oxidoreductase SAAS SAAS006311
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	cellular respiration Inferred from sequence or structural similarity. Source: RefGenome
Cellular component	cytoplasm Inferred from electronic annotation. Source: InterPro membrane Inferred from sequence or structural similarity. Source: RefGenome
Molecular function	4 iron, 4 sulfur cluster binding Inferred from electronic annotation. Source: UniProtKB-KW electron carrier activity Inferred from electronic annotation. Source: InterPro formate dehydrogenase (NAD+) activity Inferred from electronic annotation. Source: InterPro molybdenum ion binding Inferred from electronic annotation. Source: InterPro oxidoreductase activity, acting on other nitrogenous compounds as donors Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Amino acid modifications
	Non-standard residue	199	1	Selenocysteine EMBL AAC07107.1

Sequences

	Sequence		Length	Mass (Da)
	O67146 [UniParc]. Last modified February 26, 2008. Version 3. Checksum: 885529F9819563B9	FASTA	1,015	114,467
	10 20 30 40 50 60 MNYMDISRRG FLKLSVGSVG AGILGGLGFD LTPAYARVRD LKITKAKVTK SICPYCSVSC 70 80 90 100 110 120 GILAYSLSDG AMNVKERIIH VEGNPDDPIN RGTLCPKGAT LRDFVNAPDR LTKPLYRPAG 130 140 150 160 170 180 STEWKEISWD EAIEKFARWV KDTRDRTFIH KDKAGRVVNR CDSIVWAVGS PLGNEEGWLM 190 200 210 220 230 240 VKIGIALGLS ARETQATIUH APTVASLAPT FGRGAMTNNW VDISNSDLVF VMGGNPAENH 250 260 270 280 290 300 PCGFKWAIKA REKRGAKIIC IDPRFNRTAA VADIFVQIRP GTDIAFLGGL INYVLQNEKY 310 320 330 340 350 360 QKEYVRLHTT GPFIVREDFG FKDGLFTGYD PKTRSYDTTT WDYEFDPATG YPKMDPEMKH 370 380 390 400 410 420 PRCVLNILKE HYSRYTPEVV SQICGCSKED FLRVAEEVAK CGAPNKFMTI LYALGWTHHS 430 440 450 460 470 480 YGTQLIRTAC MLQLLLGNIG CPGGGINALR GHSNVQGMTD LAGQNKNLPT YIKPPKPEEQ 490 500 510 520 530 540 TLAQHLKNRT PRKLHPTSLN YWANYPKFFI SFLKCMWGDA ATPENDFAYD YLYKPEGGYN 550 560 570 580 590 600 SWDKFIDDMY KGKIEGVVTA ALNFLNNTPN AKKTVRALKN LKWMVVMDPF MIETAQFWKA 610 620 630 640 650 660 EGLDPKEVKT EILVLPTAVF LEKEGSFTNS ARWVKWKYKA TDPPGDAKDE FWIFGRFFMK 670 680 690 700 710 720 LKEFYEKEGG AFPEPILNLV WPYKNPYYPT AEEILTEING YYTRDVDGHK KGERVRLFTD 730 740 750 760 770 780 LRDDGSTACG GWLYCGVFPP EGNLAKRTDL SDPLGLGTYP NYAWNWPANR RVLYNRASCD 790 800 810 820 830 840 EKGRPWDPER PLLRWDPERD MWVGDIPDYP ATAPPEKGIG AFIMLPEGKG RLFAAKSYVT 850 860 870 880 890 900 FKDGPLPEHY EPYESPVTNI LHPNVPHNPV AKVYKSDLDL LGTPDKFPHV ATTYRLTEHY 910 920 930 940 950 960 HFWTKHLYGP SLLAPVMFIE IPEELAKEKG IQNGDLVRVS TARASIEAIA LVTKRIKPLK 970 980 990 1000 1010 VAGKTVYTIG IPIHWGFEGL VKGAITNFIT PNVWDPNSRT PEFKGFLANI EKVKT

References

[1]	"The complete genome of the hyperthermophilic bacterium Aquifex aeolicus." Deckert G., Warren P.V., Gaasterland T., Young W.G., Lenox A.L., Graham D.E., Overbeek R., Snead M.A., Keller M., Aujay M., Huber R., Feldman R.A., Short J.M., Olsen G.J., Swanson R.V. Nature 392:353-358(1998) [PubMed: 9537320] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: VF5.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE000657 Genomic DNA. Translation: AAC07107.1.
RefSeq	NP_213709.1. NC_000918.1.
3D structure databases
ProteinModelPortal	O67146.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1193780.
GenomeReviews	Gene locus aq_1039 in contig AE000657_GR.
KEGG	aae:aq_1039.
PATRIC	20959376. VBIAquAeo85532_0810.
Phylogenomic databases
HOGENOM	HBG436656.
OMA	GWVTEAM.
PhylomeDB	O67146.
Family and domain databases
InterPro	IPR009010. Asp_de-COase-like_fold. IPR006443. Formate_DH_asu_anaerob. IPR006657. MoPterin_dinucl-bd_dom. IPR006656. Mopterin_OxRdtase. IPR006963. Mopterin_OxRdtase_Fe4S4_dom. IPR006655. Mopterin_OxRdtase_prok_CS. IPR006311. TAT_signal. [Graphical view]
Gene3D	G3DSA:2.40.40.20. Asp_decarboxylase-like_fold. 1 hit.
KO	K00123.
Pfam	PF04879. Molybdop_Fe4S4. 1 hit. PF00384. Molybdopterin. 1 hit. PF01568. Molydop_binding. 1 hit. [Graphical view]
SMART	SM00926. Molybdop_Fe4S4. 1 hit. [Graphical view]
SUPFAM	SSF50692. Asp_decarb_fold. 1 hit.
TIGRFAMs	TIGR01553. Formate-DH-alph. 1 hit.
PROSITE	PS00551. MOLYBDOPTERIN_PROK_1. 1 hit. PS51318. TAT. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

O67146_AQUAE

Accession

Primary (citable) accession number: O67146

Entry history

Integrated into UniProtKB/TrEMBL:	August 1, 1998
Last sequence update:	February 26, 2008
Last modified:	January 25, 2012
This is version 74 of the entry and version 3 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)