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O67139 (SELD_AQUAE) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 71. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Selenide, water dikinase
EC=2.7.9.3
Alternative name(s):
Selenium donor protein
Selenophosphate synthase
Gene names
Name:selD
Ordered Locus Names:aq_1030
OrganismAquifex aeolicus (strain VF5)
Taxonomic identifier224324 [NCBI]
Taxonomic lineageBacteria › Aquificae › Aquificales › Aquificaceae › Aquifex

Protein attributes

Sequence length336 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Synthesizes selenophosphate from selenide and ATP By similarity. HAMAP MF_00625

Catalytic activity

ATP + selenide + H2O = AMP + selenophosphate + phosphate. HAMAP MF_00625

Cofactor

Magnesium By similarity. HAMAP MF_00625

Sequence similarities

Belongs to the selenophosphate synthase 1 family. Class I subfamily.

Sequence caution

The sequence AAC07095.1 differs from that shown. Reason: Erroneous termination at position 13. Translated as Sec.

Ontologies

Keywords
   Coding sequence diversitySelenocysteine
   LigandATP-binding
Magnesium
Nucleotide-binding
Selenium
   Molecular functionKinase
Transferase
   Technical term3D-structure
Complete proteome
Reference proteome
Gene Ontology (GO)
   Molecular functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

selenide, water dikinase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 336336Selenide, water dikinase HAMAP MF_00625
PRO_0000127614

Regions

Nucleotide binding222 – 2287ATP Potential

Sites

Active site131 Potential
Site161Important for catalytic activity By similarity

Amino acid modifications

Non-standard residue131Selenocysteine Potential

Secondary structure

1 ....................................................... 336
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
O67139 [UniParc].

Last modified February 26, 2008. Version 3.
Checksum: 035E32948AB4755B

FASTA33636,856
        10         20         30         40         50         60 
MVELLKLVRS SGUAAKVGPG DLQEILKGFN IYTDESTLVS IGDDAGVYEH NGIIWVYTVD 

        70         80         90        100        110        120 
IITPVVNDPY LWGAISTANA LSDVYAMGGI PVNALAISCF NNCELDIEIF REVIRGALDK 

       130        140        150        160        170        180 
LREAKTVLLG GHTIDDKEPK FGLSVAGICP EGKYITQSGA QVGQLLILTK PIGTGILIKG 

       190        200        210        220        230        240 
LKEGILKEED INEAIENMLA LNDKARNLML SLDATACTDV TGFGLLGHAW NICKNSNIGA 

       250        260        270        280        290        300 
RIFFEKVPYY QLSENLVKKK IYPKGAIENL NFVKNYLKSN LDNWKLILLS DPVTSGGLLF 

       310        320        330 
TINKEKLEKI DETAKELEVN YWIIGETIAE NVLEVL

« Hide

References

[1]"The complete genome of the hyperthermophilic bacterium Aquifex aeolicus."
Deckert G., Warren P.V., Gaasterland T., Young W.G., Lenox A.L., Graham D.E., Overbeek R., Snead M.A., Keller M., Aujay M., Huber R., Feldman R.A., Short J.M., Olsen G.J., Swanson R.V.
Nature 392:353-358(1998) [PubMed: 9537320] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: VF5.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE000657 Genomic DNA. Translation: AAC07095.1. Sequence problems.
PIRH70388.
RefSeqNP_213702.1. NC_000918.1.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
2YYEX-ray2.10A/B1-336[»]
2ZAUX-ray2.00A/B/C27-336[»]
2ZODX-ray1.98A/B1-336[»]
ProteinModelPortalO67139.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1193773.
GenomeReviewsGene locus aq_1030 in contig AE000657_GR.
KEGGaae:aq_1030.
PATRIC20959364. VBIAquAeo85532_0804.

Phylogenomic databases

HOGENOMHBG383791.
OMAGGHTIED.
PhylomeDBO67139.
ProtClustDBCLSK2748400.

Family and domain databases

HAMAPMF_00625. SelD.
[Tree]
InterProIPR000728. AIR_synth.
IPR010918. AIR_synth_C.
IPR016188. PurM_N-like.
IPR004536. SelD.
IPR023061. SelD_I.
[Graphical view]
KOK01008.
PfamPF00586. AIRS. 1 hit.
PF02769. AIRS_C. 1 hit.
[Graphical view]
PIRSFPIRSF036407. Selenphspht_syn. 1 hit.
SUPFAMSSF56042. AIR_synth_C. 1 hit.
SSF55326. PurM_N-like. 1 hit.
TIGRFAMsTIGR00476. SelD. 1 hit.
ProtoNetSearch...

Entry information

Entry nameSELD_AQUAE
AccessionPrimary (citable) accession number: O67139
Entry history
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: February 26, 2008
Last modified: January 25, 2012
This is version 71 of the entry and version 3 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

SIMILARITY comments

Index of protein domains and families

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