O67092 (O67092_AQUAE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Hydrogenase large subunit EMBL AAC07046.1

Gene names

Name:	mbhL2 EMBL AAC07046.1
Ordered Locus Names:	aq_960

Organism

Aquifex aeolicus (strain VF5)

Taxonomic identifier

224324 [NCBI]

Taxonomic lineage

Bacteria › Aquificae › Aquificales › Aquificaceae › Aquifex

Protein attributes

Sequence length	564 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. RuleBase RU003896

Ontologies

Keywords
Ligand	Metal-binding RuleBase RU003896 Nickel RuleBase RU003896
Molecular function	Oxidoreductase RuleBase RU003896
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Molecular function	ferredoxin hydrogenase activity Inferred from electronic annotation. Source: InterPro nickel cation binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	O67092 [UniParc]. Last modified August 1, 1998. Version 1. Checksum: 42768ABD16512754	FASTA	564	64,738
	10 20 30 40 50 60 MKRVVVDPVT RIEGHLRIEA EVKDGKITKA YSSGTMVRGI EIILKGRDPR EAWAFAQRIC 70 80 90 100 110 120 GVCTTVHAIA SVRAVEDALS INVPVNASLL RKLIIGTIFV HDHVVHFYHL HLLDWVNPVQ 130 140 150 160 170 180 ALKADPYETS RLAQSLSNYE KSTPGYFREV QKKIKQQVER GQLGIFNKGY WNHPEYKLPP 190 200 210 220 230 240 ELNLMLIAHY LDALDWQTRI VQVHTIIGGK NPHPNFAVGG MAAPINPESD TAINMEKLGR 250 260 270 280 290 300 IKTLIDEMYD FTVKVYLPDI KVLGKYYKDW FFKGEGLGNF LVLGEPEKDS WREGKWFIPP 310 320 330 340 350 360 TFIKGRNLKD FEEVNINEVK EYVTHSWYKY SVGDDKPLHP WEGETNLNYT GPKPPYEYLN 370 380 390 400 410 420 VEGKYSWLKA PRYKDYSVEV GPLSRILALY ARDMYGIREE VEKHLKEMDV PFEGMFSTMG 430 440 450 460 470 480 RTFARALETK LYSFSMKNWF SELMENVKKG NYDVFNPEKW EPSTWPKETK GVGFMEAPRG 490 500 510 520 530 540 SLSHWVHIKD GKLENYQAVV PTTWNASPRD AKGNPSAYEA SLVGHSLHNP KEPVEILRTI 550 560 HSFDPCLACA VHLYGDEEME IRVV

References

[1]	"The complete genome of the hyperthermophilic bacterium Aquifex aeolicus." Deckert G., Warren P.V., Gaasterland T., Young W.G., Lenox A.L., Graham D.E., Overbeek R., Snead M.A., Keller M., Aujay M., Huber R., Feldman R.A., Short J.M., Olsen G.J., Swanson R.V. Nature 392:353-358(1998) [PubMed: 9537320] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: VF5.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE000657 Genomic DNA. Translation: AAC07046.1.
PIR	A70383.
RefSeq	NP_213655.1. NC_000918.1.
3D structure databases
HSSP	HSSP built from PDB template 2FRV based on UniProtKB P12944.
ProteinModelPortal	O67092.
ModBase	Search...
Protein family/group databases
TCDB	3.D.7.2.1. H2:heterodisulfide oxidoreductase (HHO) family.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1193634.
GenomeReviews	Gene locus aq_960 in contig AE000657_GR.
KEGG	aae:aq_960.
NMPDR	fig|224324.1.peg.670.
PATRIC	20959260. VBIAquAeo85532_0752.
Phylogenomic databases
HOGENOM	HBG733231.
OMA	PIPRIEG.
PhylomeDB	O67092.
ProtClustDB	CLSK2748390.
Family and domain databases
InterPro	IPR001501. Ni-dep_hyd_lsu. IPR018194. Ni-dep_hyd_lsu_Ni_BS. [Graphical view]
KO	K06281.
Pfam	PF00374. NiFeSe_Hases. 1 hit. [Graphical view]
PROSITE	PS00507. NI_HGENASE_L_1. 1 hit. PS00508. NI_HGENASE_L_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

O67092_AQUAE

Accession

Primary (citable) accession number: O67092

Entry history

Integrated into UniProtKB/TrEMBL:	August 1, 1998
Last sequence update:	August 1, 1998
Last modified:	January 25, 2012
This is version 65 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)