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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Aquifex aeolicus (strain VF5)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciAAEO224324:G1G15-656-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligase (EC:6.1.1.19)
Alternative name(s):
Arginyl-tRNA synthetase
Short name:
ArgRS
Gene namesi
Name:argS
Ordered Locus Names:aq_923
OrganismiAquifex aeolicus (strain VF5)
Taxonomic identifieri224324 [NCBI]
Taxonomic lineageiBacteriaAquificaeAquificalesAquificaceaeAquifex
Proteomesi
  • UP000000798 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001515241 – 583Arginine--tRNA ligaseAdd BLAST583

Proteomic databases

PRIDEiO67068

Interactioni

Subunit structurei

Monomer.By similarity

Protein-protein interaction databases

STRINGi224324.aq_923

Structurei

3D structure databases

ProteinModelPortaliO67068
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi121 – 131"HIGH" regionAdd BLAST11

Sequence similaritiesi

Phylogenomic databases

eggNOGiENOG4105C75 Bacteria
COG0018 LUCA
HOGENOMiHOG000247214
InParanoidiO67068
KOiK01887
OMAiNKPLHLG
OrthoDBiPOG091H01RF

Family and domain databases

CDDicd00671 ArgRS_core, 1 hit
Gene3Di3.30.1360.70, 1 hit
3.40.50.620, 1 hit
HAMAPiMF_00123 Arg_tRNA_synth, 1 hit
InterProiView protein in InterPro
IPR001412 aa-tRNA-synth_I_CS
IPR001278 Arg-tRNA-ligase
IPR005148 Arg-tRNA-synth_N
IPR036695 Arg-tRNA-synth_N_sf
IPR035684 ArgRS_core
IPR008909 DALR_anticod-bd
IPR014729 Rossmann-like_a/b/a_fold
IPR009080 tRNAsynth_Ia_anticodon-bd
PANTHERiPTHR11956 PTHR11956, 1 hit
PfamiView protein in Pfam
PF03485 Arg_tRNA_synt_N, 1 hit
PF05746 DALR_1, 1 hit
PF00750 tRNA-synt_1d, 1 hit
PRINTSiPR01038 TRNASYNTHARG
SMARTiView protein in SMART
SM01016 Arg_tRNA_synt_N, 1 hit
SM00836 DALR_1, 1 hit
SUPFAMiSSF47323 SSF47323, 1 hit
SSF55190 SSF55190, 1 hit
TIGRFAMsiTIGR00456 argS, 1 hit
PROSITEiView protein in PROSITE
PS00178 AA_TRNA_LIGASE_I, 1 hit

Sequencei

Sequence statusi: Complete.

O67068-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKELVKEKVL KALKELYNTQ VENFKVEKPK EEAHGDLASN VAFLLARELK
60 70 80 90 100
KPPVNIAQEL ADFLSKDETF KSVEAVKGFI NFRFSEDFLK EEFKKFLLSG
110 120 130 140 150
EAYFKEDLGK GLKVQLEYVS ANPTGPLHLG HGRGAVVGDT LARLFKFFNY
160 170 180 190 200
DVTREYYIND AGRQVYLLGI SIYYRYLEKC PERDEETFKE IKEIFEKDGY
210 220 230 240 250
RGEYVKEIAE RLRKLVGESL CKPEEANLKE VREKILKEES IELYYTKKYE
260 270 280 290 300
PKDVVDLLSN YGLDLMMKEI REDLSLMDIS FDVWFSERSL YDSGEVERLI
310 320 330 340 350
NLLKEKGYVY EKDGALWLKT SLFGDDKDRV VKRSDGTYTY FASDIAYHYN
360 370 380 390 400
KFKRGFEKVI NVWGADHHGY IPRVKAALKM LEIPEDWLEI LLVQMVKLFR
410 420 430 440 450
EGKEVKMSKR AGTFVTLREL LDEVGKDAVR FIFLTKRSDT PLDFDVEKAK
460 470 480 490 500
EKSSENPVYY VQYAHARISG IFREFKERYK KDVSVEELIN YVQHLEEEAE
510 520 530 540 550
IKLIKKVLFF KDELVDITLK REPHLLTYYL IDLAGDFHHY YNHHRILGME
560 570 580
ENVMFSRLAL VKGIKEVVRL GLNLMGVSAP ERM
Length:583
Mass (Da):68,319
Last modified:August 1, 1998 - v1
Checksum:i350807CA39C1220B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000657 Genomic DNA Translation: AAC07033.1
PIRiA70380
RefSeqiNP_213630.1, NC_000918.1
WP_010880568.1, NC_000918.1

Genome annotation databases

EnsemblBacteriaiAAC07033; AAC07033; aq_923
GeneIDi1193610
KEGGiaae:aq_923
PATRICifig|224324.8.peg.723

Similar proteinsi

Entry informationi

Entry nameiSYR_AQUAE
AccessioniPrimary (citable) accession number: O67068
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: August 1, 1998
Last modified: May 23, 2018
This is version 117 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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