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Protein

Phosphate-specific transport system accessory protein PhoU homolog

Gene

phoU

Organism
Aquifex aeolicus (strain VF5)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Plays a role in the regulation of phosphate uptake. In this role, it may bind, possibly as a chaperone, to PhoR, PhoB or a PhoR-PhoB complex to promote dephosphorylation of phospho-PhoB, or inhibit formation of the PhoR-PhoB transitory complex (Probable).Curated

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Phosphate transport, Transport

Enzyme and pathway databases

BioCyciAAEO224324:GJBH-647-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphate-specific transport system accessory protein PhoU homolog
Short name:
Pst system accessory protein PhoU homolog
Alternative name(s):
PhoU-like phosphate uptake regulator
Gene namesi
Name:phoU
Ordered Locus Names:aq_906
OrganismiAquifex aeolicus (strain VF5)
Taxonomic identifieri224324 [NCBI]
Taxonomic lineageiBacteriaAquificaeAquificalesAquificaceaeAquifex
Proteomesi
  • UP000000798 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

  • cytoplasm Source: UniProtKB
  • plasma membrane Source: GO_Central
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 221221Phosphate-specific transport system accessory protein PhoU homologPRO_0000155163Add
BLAST

Interactioni

Subunit structurei

Homodimer.1 Publication

GO - Molecular functioni

  • protein homodimerization activity Source: UniProtKB

Protein-protein interaction databases

STRINGi224324.aq_906.

Structurei

Secondary structure

221
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Helixi1 – 3333Combined sources
Helixi37 – 459Combined sources
Helixi47 – 6822Combined sources
Helixi72 – 10635Combined sources
Helixi115 – 13622Combined sources
Helixi140 – 17031Combined sources
Helixi172 – 1743Combined sources
Helixi175 – 20834Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1T72X-ray2.90A/B/D/E/F/G1-221[»]
1T8BX-ray3.23A/B1-221[»]
ProteinModelPortaliO67053.
SMRiO67053. Positions 1-209.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiO67053.

Family & Domainsi

Sequence similaritiesi

Belongs to the PhoU family.Curated

Phylogenomic databases

eggNOGiENOG4108UTW. Bacteria.
COG0704. LUCA.
HOGENOMiHOG000074026.
InParanoidiO67053.
KOiK02039.
OMAiELATYMM.
OrthoDBiPOG091H01TR.

Family and domain databases

InterProiIPR028366. P_trasport_PhoU.
IPR026022. PhoU_dom.
[Graphical view]
PANTHERiPTHR10010:SF14. PTHR10010:SF14. 1 hit.
PfamiPF01895. PhoU. 2 hits.
[Graphical view]
PIRSFiPIRSF003107. PhoU. 1 hit.
TIGRFAMsiTIGR02135. phoU_full. 1 hit.

Sequencei

Sequence statusi: Complete.

O67053-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKLFKELEET KEQVIKMAKL VQEAIDKATE ALNKQNVELA EEVIKGDDTI
60 70 80 90 100
DLLEVDIERR CIRMIALYQP EAGDLRMIMG IYKIVSDLER MGDEAENIAE
110 120 130 140 150
RAILLAEEPP LKPYVNINFM SEIVKEMVND SVISFIQQDT LLAKKVIEKD
160 170 180 190 200
DTVDELYHQL ERELMTYVLE DPRNIKRAMH LSFVARHYER IADHAENVAE
210 220
AAIYLSEGEI VKHQHIKEKG E
Length:221
Mass (Da):25,567
Last modified:August 1, 1998 - v1
Checksum:i42C83425B0EB5D84
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000657 Genomic DNA. Translation: AAC07012.1.
PIRiB70378.
RefSeqiNP_213615.1. NC_000918.1.
WP_010880553.1. NC_000918.1.

Genome annotation databases

EnsemblBacteriaiAAC07012; AAC07012; aq_906.
GeneIDi1193595.
KEGGiaae:aq_906.
PATRICi20959168. VBIAquAeo85532_0707.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000657 Genomic DNA. Translation: AAC07012.1.
PIRiB70378.
RefSeqiNP_213615.1. NC_000918.1.
WP_010880553.1. NC_000918.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1T72X-ray2.90A/B/D/E/F/G1-221[»]
1T8BX-ray3.23A/B1-221[»]
ProteinModelPortaliO67053.
SMRiO67053. Positions 1-209.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi224324.aq_906.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC07012; AAC07012; aq_906.
GeneIDi1193595.
KEGGiaae:aq_906.
PATRICi20959168. VBIAquAeo85532_0707.

Phylogenomic databases

eggNOGiENOG4108UTW. Bacteria.
COG0704. LUCA.
HOGENOMiHOG000074026.
InParanoidiO67053.
KOiK02039.
OMAiELATYMM.
OrthoDBiPOG091H01TR.

Enzyme and pathway databases

BioCyciAAEO224324:GJBH-647-MONOMER.

Miscellaneous databases

EvolutionaryTraceiO67053.

Family and domain databases

InterProiIPR028366. P_trasport_PhoU.
IPR026022. PhoU_dom.
[Graphical view]
PANTHERiPTHR10010:SF14. PTHR10010:SF14. 1 hit.
PfamiPF01895. PhoU. 2 hits.
[Graphical view]
PIRSFiPIRSF003107. PhoU. 1 hit.
TIGRFAMsiTIGR02135. phoU_full. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiPHOU_AQUAE
AccessioniPrimary (citable) accession number: O67053
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: August 1, 1998
Last modified: September 7, 2016
This is version 100 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.