O66986 (GCP_AQUAE) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable tRNA threonylcarbamoyladenosine biosynthesis protein Gcp

Alternative name(s):
t(6)A37 threonylcarbamoyladenosine biosynthesis protein

Gene names

Name:	gcp
Ordered Locus Names:	aq_801

Organism

Aquifex aeolicus (strain VF5)

Taxonomic identifier

224324 [NCBI]

Taxonomic lineage

Bacteria › Aquificae › Aquificales › Aquificaceae › Aquifex

Protein attributes

Sequence length	335 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t6A37) in tRNAs that read codons beginning with adenine By similarity. HAMAP MF_01445
Subcellular location	Cytoplasm Potential HAMAP MF_01445.
Sequence similarities	Belongs to the KAE1 / YgjD family.

Ontologies

Keywords
Biological process	tRNA processing
Cellular component	Cytoplasm
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	proteolysis Inferred from electronic annotation. Source: InterPro tRNA processing Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	metalloendopeptidase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 335	335	Probable tRNA threonylcarbamoyladenosine biosynthesis protein Gcp HAMAP MF_01445		PRO_0000096956

Sequences

	Sequence		Length	Mass (Da)
	O66986 [UniParc]. Last modified August 1, 1998. Version 1. Checksum: D3B1606646908EC1	FASTA	335	37,370
	10 20 30 40 50 60 MRTLAVETSC DETALAIYDD QKGVLGNVIL SQAVVHSPFG GVVPELSARE HTRNILPIFD 70 80 90 100 110 120 RLLKESRINL EEIDFISFTL TPGLILSLVV GVAFAKALAY EYRKPLVPVH HLEGHIYSVF 130 140 150 160 170 180 LEKKVEYPFL ALIISGGHTD LYLVRDFGRY DFLGGTLDDA VGEAYDKVAK MLGLGYPGGP 190 200 210 220 230 240 IIDRLAKEGK KLYPLPKPLM EEGNLNFSFS GLKTAILNLL KKEKNVRKED IAYSFQETVV 250 260 270 280 290 300 EILLEKSLWA MKKTGIKRLV VVGGVSANSR LREVFKKASQ EYGFELYIPH PSLSTDNALM 310 320 330 IAYAGMERFK RGVVAPLDVN PQPNIPLEEF GRIWT

References

[1]

"The complete genome of the hyperthermophilic bacterium Aquifex aeolicus." Deckert G., Warren P.V., Gaasterland T., Young W.G., Lenox A.L., Graham D.E., Overbeek R., Snead M.A., Keller M., Aujay M., Huber R., Feldman R.A., Short J.M., Olsen G.J., Swanson R.V. Nature 392:353-358(1998) [PubMed: 9537320] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: VF5.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE000657 Genomic DNA. Translation: AAC06951.1.
PIR	G70369.
RefSeq	NP_213547.1. NC_000918.1.
3D structure databases
ProteinModelPortal	O66986.
ModBase	Search...
Protein family/group databases
MEROPS	M22.A01.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1193436.
GenomeReviews	Gene locus aq_801 in contig AE000657_GR.
KEGG	aae:aq_801.
NMPDR	fig|224324.1.peg.562.
PATRIC	20959002. VBIAquAeo85532_0632.
Phylogenomic databases
HOGENOM	HBG304663.
OMA	PAVGVHH.
PhylomeDB	O66986.
ProtClustDB	PRK09604.
Enzyme and pathway databases
BioCyc	AAEO224324:AQ_801-MONOMER.
Family and domain databases
HAMAP	MF_01445. gcp. [Tree]
InterPro	IPR022450. Pept_M22_O-sialoglycopept. IPR000905. Peptidase_M22. IPR017860. Peptidase_M22_CS. IPR017861. Peptidase_M22_subgr. [Graphical view]
KO	K01409.
Pfam	PF00814. Peptidase_M22. 1 hit. [Graphical view]
PRINTS	PR00789. OSIALOPTASE.
TIGRFAMs	TIGR03723. Bact_gcp. 1 hit. TIGR00329. Gcp_kae1. 1 hit.
PROSITE	PS01016. GLYCOPROTEASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GCP_AQUAE

Accession

Primary (citable) accession number: O66986

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 30, 2000
Last sequence update:	August 1, 1998
Last modified:	January 25, 2012
This is version 77 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program