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Protein
Submitted name:

Cation efflux (AcrB/AcrD/AcrF family)

Gene

acrD4

Organism
Aquifex aeolicus (strain VF5)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Cation efflux (AcrB/AcrD/AcrF family)Imported
Gene namesi
Name:acrD4Imported
Ordered Locus Names:aq_786Imported
OrganismiAquifex aeolicus (strain VF5)Imported
Taxonomic identifieri224324 [NCBI]
Taxonomic lineageiBacteriaAquificaeAquificalesAquificaceaeAquifex
Proteomesi
  • UP000000798 Componenti: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei12 – 30HelicalSequence analysisAdd BLAST19
Transmembranei326 – 346HelicalSequence analysisAdd BLAST21
Transmembranei353 – 374HelicalSequence analysisAdd BLAST22
Transmembranei380 – 403HelicalSequence analysisAdd BLAST24
Transmembranei423 – 444HelicalSequence analysisAdd BLAST22
Transmembranei456 – 484HelicalSequence analysisAdd BLAST29
Transmembranei515 – 532HelicalSequence analysisAdd BLAST18
Transmembranei836 – 859HelicalSequence analysisAdd BLAST24
Transmembranei866 – 886HelicalSequence analysisAdd BLAST21
Transmembranei892 – 913HelicalSequence analysisAdd BLAST22
Transmembranei941 – 963HelicalSequence analysisAdd BLAST23
Transmembranei969 – 992HelicalSequence analysisAdd BLAST24

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Interactioni

Protein-protein interaction databases

STRINGi224324.aq_786.

Structurei

3D structure databases

ProteinModelPortaliO66977.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. [View classification]SAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG4105BZS. Bacteria.
COG0841. LUCA.
HOGENOMiHOG000158128.
InParanoidiO66977.
OMAiMEFFREL.
OrthoDBiPOG091H01EK.

Family and domain databases

Gene3Di3.30.2090.10. 2 hits.
InterProiIPR027463. AcrB_DN_DC_subdom.
IPR001036. Acrflvin-R.
[Graphical view]
PfamiPF00873. ACR_tran. 1 hit.
[Graphical view]
PRINTSiPR00702. ACRIFLAVINRP.
SUPFAMiSSF82714. SSF82714. 2 hits.

Sequencei

Sequence statusi: Complete.

O66977-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQKFFIERPV TAFMLMLSFV FLGLYSLKLV PIDRLPDVEF PVVRISADYP
60 70 80 90 100
GADPYVVDTN VTRIIEEAVS TVSGIESIIS RSYPGFASVV VTFTLDKDID
110 120 130 140 150
VATQEVSNAI QRAMRRFPKG VEPPTVVKVD TSVAPIMVLL LYSDTADYQR
160 170 180 190 200
LTYYADKVIK RELEKLYGVG SVSLGGFRDN VLWVRLKVSE LYGYELTPLD
210 220 230 240 250
VLREIDKNHQ DIPAGNVYGK RREYILRLYG KFKTPEELSN LYIKENLRLG
260 270 280 290 300
DVARVYFGED EERSLARFNG NRAVALLVFK QAKVNTVRVI DEIKSRMEFF
310 320 330 340 350
RELLPPDIKL DYTFDASVYV KESIRAAFEE IIIGVFLTAF TVYLFLGNLR
360 370 380 390 400
LTLVPVFAIP VTILGTIFFL YQLGYSLNTI TLLALAVAVG IVIDDAIVVM
410 420 430 440 450
ESIHRRREEG LPPFEAGVKG TRVVMFALLA STSVLIVVFL PVVFLKGVLG
460 470 480 490 500
TFLKNFALTL IIAIGLSYLV AITFTPSATV RLITQRPREN FFMKLYKRFE
510 520 530 540 550
GSFDKALRFS LDHKFIVLLL SFFFVGLSVY LFPKVKKEFV PHVDEGRFMV
560 570 580 590 600
RMRMPVGTSF ERVKEKAKEV ERILLKNPHI AKVGMVVGEG VGGAGVHSGL
610 620 630 640 650
FFVYLKERSQ RPHQMVVMSE VRRELSELKN VKVSVEPPHG IGASAGRTTD
660 670 680 690 700
LQYIVRGERI EVLKKIAKSM EEHFSNVEGF RDVDTSLELS APYVKISVKR
710 720 730 740 750
EKLSHLGVSV EDLGLTLSLL FGKYRVGTYE LGSESYDFYI KAEEDFVKEI
760 770 780 790 800
HNLNRVYIRA RNGELIPITE LIDFSIEAGP FSLTRYNRQY SFVFYANLEG
810 820 830 840 850
IDLATARSLV EDWLKKNLPF GYTYDTAGRV KEFKKAFSGF VLSLAMSLIG
860 870 880 890 900
VYMILASLFE SLKHPFTVLL MVPLSALGVF GFMYLTDTSL NVSSYFGIIL
910 920 930 940 950
LVGIIVRDAV LFIERIIQLR KEGYAVREAI LEARRERLRP ILMTTITVVS
960 970 980 990 1000
ALLPVALGLT AGSEQRKPLA IAVIGGIASG LPLSLFLLPV LYELMEWKRK
Length:1,000
Mass (Da):112,872
Last modified:August 1, 1998 - v1
Checksum:i446A76D05462947B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000657 Genomic DNA. Translation: AAC06934.1.
PIRiF70368.
RefSeqiNP_213538.1. NC_000918.1.
WP_010880476.1. NC_000918.1.

Genome annotation databases

EnsemblBacteriaiAAC06934; AAC06934; aq_786.
GeneIDi1193427.
KEGGiaae:aq_786.
PATRICi20958984. VBIAquAeo85532_0623.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000657 Genomic DNA. Translation: AAC06934.1.
PIRiF70368.
RefSeqiNP_213538.1. NC_000918.1.
WP_010880476.1. NC_000918.1.

3D structure databases

ProteinModelPortaliO66977.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi224324.aq_786.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC06934; AAC06934; aq_786.
GeneIDi1193427.
KEGGiaae:aq_786.
PATRICi20958984. VBIAquAeo85532_0623.

Phylogenomic databases

eggNOGiENOG4105BZS. Bacteria.
COG0841. LUCA.
HOGENOMiHOG000158128.
InParanoidiO66977.
OMAiMEFFREL.
OrthoDBiPOG091H01EK.

Family and domain databases

Gene3Di3.30.2090.10. 2 hits.
InterProiIPR027463. AcrB_DN_DC_subdom.
IPR001036. Acrflvin-R.
[Graphical view]
PfamiPF00873. ACR_tran. 1 hit.
[Graphical view]
PRINTSiPR00702. ACRIFLAVINRP.
SUPFAMiSSF82714. SSF82714. 2 hits.
ProtoNetiSearch...

Entry informationi

Entry nameiO66977_AQUAE
AccessioniPrimary (citable) accession number: O66977
Entry historyi
Integrated into UniProtKB/TrEMBL: August 1, 1998
Last sequence update: August 1, 1998
Last modified: November 30, 2016
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.