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Protein

4-alpha-glucanotransferase

Gene

malQ

Organism
Aquifex aeolicus (strain VF5)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Catalytic activityi

Transfers a segment of a (1->4)-alpha-D-glucan to a new position in an acceptor, which may be glucose or a (1->4)-alpha-D-glucan.

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Keywords - Biological processi

Carbohydrate metabolism

Enzyme and pathway databases

BRENDAi2.4.1.25. 396.

Protein family/group databases

CAZyiGH77. Glycoside Hydrolase Family 77.

Names & Taxonomyi

Protein namesi
Recommended name:
4-alpha-glucanotransferase (EC:2.4.1.25)
Alternative name(s):
Amylomaltase
Disproportionating enzyme
Short name:
D-enzyme
Gene namesi
Name:malQ
Synonyms:malM
Ordered Locus Names:aq_723
OrganismiAquifex aeolicus (strain VF5)
Taxonomic identifieri224324 [NCBI]
Taxonomic lineageiBacteriaAquificaeAquificalesAquificaceaeAquifex
Proteomesi
  • UP000000798 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001701191 – 4854-alpha-glucanotransferaseAdd BLAST485

Interactioni

Protein-protein interaction databases

STRINGi224324.aq_723.

Structurei

Secondary structure

1485
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi3 – 7Combined sources5
Helixi10 – 12Combined sources3
Beta strandi16 – 19Combined sources4
Helixi24 – 36Combined sources13
Beta strandi40 – 42Combined sources3
Helixi51 – 53Combined sources3
Beta strandi63 – 65Combined sources3
Helixi68 – 70Combined sources3
Helixi74 – 78Combined sources5
Helixi84 – 86Combined sources3
Helixi97 – 113Combined sources17
Helixi118 – 127Combined sources10
Helixi129 – 145Combined sources17
Helixi149 – 151Combined sources3
Helixi154 – 157Combined sources4
Helixi161 – 170Combined sources10
Helixi172 – 198Combined sources27
Beta strandi202 – 207Combined sources6
Beta strandi213 – 215Combined sources3
Helixi216 – 220Combined sources5
Helixi222 – 224Combined sources3
Beta strandi233 – 239Combined sources7
Beta strandi243 – 247Combined sources5
Beta strandi249 – 254Combined sources6
Helixi258 – 263Combined sources6
Turni264 – 266Combined sources3
Helixi267 – 277Combined sources11
Beta strandi281 – 285Combined sources5
Helixi288 – 291Combined sources4
Beta strandi293 – 298Combined sources6
Beta strandi302 – 304Combined sources3
Beta strandi308 – 311Combined sources4
Helixi314 – 324Combined sources11
Beta strandi330 – 332Combined sources3
Helixi340 – 348Combined sources9
Beta strandi353 – 356Combined sources4
Helixi357 – 359Combined sources3
Helixi370 – 372Combined sources3
Beta strandi375 – 381Combined sources7
Helixi389 – 394Combined sources6
Helixi398 – 408Combined sources11
Helixi414 – 416Combined sources3
Helixi417 – 427Combined sources11
Beta strandi431 – 436Combined sources6
Helixi437 – 440Combined sources4
Helixi445 – 447Combined sources3
Helixi467 – 470Combined sources4
Helixi471 – 480Combined sources10

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1TZ7X-ray2.15A/B1-485[»]
ProteinModelPortaliO66937.
SMRiO66937.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiO66937.

Family & Domainsi

Sequence similaritiesi

Belongs to the disproportionating enzyme family.Curated

Phylogenomic databases

eggNOGiENOG4107SBB. Bacteria.
COG1640. LUCA.
HOGENOMiHOG000017376.
InParanoidiO66937.
KOiK00705.
OMAiEARMNFP.
OrthoDBiPOG091H0DLU.

Family and domain databases

Gene3Di3.20.20.80. 1 hit.
InterProiIPR003385. Glyco_hydro_77.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PfamiPF02446. Glyco_hydro_77. 1 hit.
[Graphical view]
SUPFAMiSSF51445. SSF51445. 1 hit.
TIGRFAMsiTIGR00217. malQ. 1 hit.

Sequencei

Sequence statusi: Complete.

O66937-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRLAGILLHV TSLPSPYGIG DLGKEAYRFL DFLKECGFSL WQVLPLNPTS
60 70 80 90 100
LEAGNSPYSS NSLFAGNYVL IDPEELLEED LIKERDLKRF PLGEALYEVV
110 120 130 140 150
YEYKKELLEK AFKNFRRFEL LEDFLKEHSY WLRDYALYMA IKEEEGKEWY
160 170 180 190 200
EWDEELKRRE KEALKRVLNK LKGRFYFHVF VQFVFFKQWE KLRRYARERG
210 220 230 240 250
ISIVGDLPMY PSYSSADVWT NPELFKLDGD LKPLFVAGVP PDFFSKTGQL
260 270 280 290 300
WGNPVYNWEE HEKEGFRWWI RRVHHNLKLF DFLRLDHFRG FEAYWEVPYG
310 320 330 340 350
EETAVNGRWV KAPGKTLFKK LLSYFPKNPF IAEDLGFITD EVRYLRETFK
360 370 380 390 400
IPGSRVIEFA FYDKESEHLP HNVEENNVYY TSTHDLPPIR GWFENLGEES
410 420 430 440 450
RKRLFEYLGR EIKEEKVNEE LIRLVLISRA KFAIIQMQDL LNLGNEARMN
460 470 480
YPGRPFGNWR WRIKEDYTQK KEFIKKLLGI YGREV
Length:485
Mass (Da):58,086
Last modified:August 1, 1998 - v1
Checksum:iD6D9B98BB90A0E22
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000657 Genomic DNA. Translation: AAC06897.1.
PIRiE70363.
RefSeqiNP_213497.1. NC_000918.1.
WP_010880435.1. NC_000918.1.

Genome annotation databases

EnsemblBacteriaiAAC06897; AAC06897; aq_723.
GeneIDi1193386.
KEGGiaae:aq_723.
PATRICi20958898. VBIAquAeo85532_0580.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000657 Genomic DNA. Translation: AAC06897.1.
PIRiE70363.
RefSeqiNP_213497.1. NC_000918.1.
WP_010880435.1. NC_000918.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1TZ7X-ray2.15A/B1-485[»]
ProteinModelPortaliO66937.
SMRiO66937.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi224324.aq_723.

Protein family/group databases

CAZyiGH77. Glycoside Hydrolase Family 77.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC06897; AAC06897; aq_723.
GeneIDi1193386.
KEGGiaae:aq_723.
PATRICi20958898. VBIAquAeo85532_0580.

Phylogenomic databases

eggNOGiENOG4107SBB. Bacteria.
COG1640. LUCA.
HOGENOMiHOG000017376.
InParanoidiO66937.
KOiK00705.
OMAiEARMNFP.
OrthoDBiPOG091H0DLU.

Enzyme and pathway databases

BRENDAi2.4.1.25. 396.

Miscellaneous databases

EvolutionaryTraceiO66937.

Family and domain databases

Gene3Di3.20.20.80. 1 hit.
InterProiIPR003385. Glyco_hydro_77.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PfamiPF02446. Glyco_hydro_77. 1 hit.
[Graphical view]
SUPFAMiSSF51445. SSF51445. 1 hit.
TIGRFAMsiTIGR00217. malQ. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiMALQ_AQUAE
AccessioniPrimary (citable) accession number: O66937
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: August 1, 1998
Last modified: November 2, 2016
This is version 101 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.