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O66935 (GLGA_AQUAE) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 77. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glycogen synthase

EC=2.4.1.21
Alternative name(s):
Starch [bacterial glycogen] synthase
Gene names
Name:glgA
Ordered Locus Names:aq_721
OrganismAquifex aeolicus (strain VF5) [Reference proteome] [HAMAP]
Taxonomic identifier224324 [NCBI]
Taxonomic lineageBacteriaAquificaeAquificalesAquificaceaeAquifex

Protein attributes

Sequence length463 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Synthesizes alpha-1,4-glucan chains using ADP-glucose By similarity. HAMAP-Rule MF_00484

Catalytic activity

ADP-glucose + (1,4-alpha-D-glucosyl)(n) = ADP + (1,4-alpha-D-glucosyl)(n+1). HAMAP-Rule MF_00484

Pathway

Glycan biosynthesis; glycogen biosynthesis. HAMAP-Rule MF_00484

Sequence similarities

Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.

Ontologies

Keywords
   Biological processGlycogen biosynthesis
   Molecular functionGlycosyltransferase
Transferase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processglycogen biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Molecular_functionstarch synthase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 463463Glycogen synthase HAMAP-Rule MF_00484
PRO_0000188589

Sites

Binding site151ADP-glucose By similarity

Sequences

Sequence LengthMass (Da)Tools
O66935 [UniParc].

Last modified August 1, 1998. Version 1.
Checksum: D896172D0D3DB27D

FASTA46353,457
        10         20         30         40         50         60 
MRVLFCSSEI YPYAKTGGLA DFSFCLIKYL KKYGVKVKGV MPYYKTLKAE NLRKTDKGVT 

        70         80         90        100        110        120 
LNLNGKDYTF EVYESEDCYF LRNDELFGRD YIYGPPGWGY EDNDIRFGGF SRAVSELIST 

       130        140        150        160        170        180 
GQLEADVVHA NDWQTALIPL FLKEVFKTPV KTVFTIHNLA YQGLFPKETV ERVGIPPYLF 

       190        200        210        220        230        240 
HMEAVEFWGL VNFMKGGIVF SDLITTVSPT YAKEIQTQEY GYGLEGVLKK YSYKLRGILN 

       250        260        270        280        290        300 
GIDYEVWNPE KDKYIYQNYS LRNYSKKFKN KEFLSKELGI EAEKPLISFI NRFTHQKGVE 

       310        320        330        340        350        360 
LILNCAEEMS KLNANFVFLG TGEYENAFLD VSKIYKNFKV FAEFNEGFAR KLYASSDFIL 

       370        380        390        400        410        420 
MPSYFEPCGL TQMIGMRYGC VPIVRKTGGL RDTVKDISEG GYGITFEEPS KETFLCSLKR 

       430        440        450        460 
AIELYENAKK FRNSVKIVMS LDFSCDRMTK EYIECYEEVQ SHQ 

« Hide

References

[1]"The complete genome of the hyperthermophilic bacterium Aquifex aeolicus."
Deckert G., Warren P.V., Gaasterland T., Young W.G., Lenox A.L., Graham D.E., Overbeek R., Snead M.A., Keller M., Aujay M., Huber R., Feldman R.A., Short J.M., Olsen G.J., Swanson R.V.
Nature 392:353-358(1998) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: VF5.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE000657 Genomic DNA. Translation: AAC06894.1.
PIRC70363.
RefSeqNP_213495.1. NC_000918.1.

3D structure databases

ProteinModelPortalO66935.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING224324.aq_721.

Protein family/group databases

CAZyGT5. Glycosyltransferase Family 5.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAC06894; AAC06894; aq_721.
GeneID1193384.
KEGGaae:aq_721.
PATRIC20958894. VBIAquAeo85532_0578.

Phylogenomic databases

eggNOGCOG0297.
HOGENOMHOG000294940.
KOK00703.
OMAPYHDESQ.
OrthoDBEOG6JTC6Z.

Enzyme and pathway databases

BioCycAAEO224324:GJBH-519-MONOMER.
UniPathwayUPA00164.

Family and domain databases

HAMAPMF_00484. Glycogen_synth.
InterProIPR001296. Glyco_trans_1.
IPR011835. Glycogen/starch_synth.
IPR013534. Starch_synth_cat_dom.
[Graphical view]
PfamPF08323. Glyco_transf_5. 1 hit.
PF00534. Glycos_transf_1. 1 hit.
[Graphical view]
TIGRFAMsTIGR02095. glgA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameGLGA_AQUAE
AccessionPrimary (citable) accession number: O66935
Entry history
Integrated into UniProtKB/Swiss-Prot: November 16, 2001
Last sequence update: August 1, 1998
Last modified: May 14, 2014
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways