Reviewed, UniProtKB/Swiss-Prot O66935 (GLGA_AQUAE)

Names and origin

Protein names

Recommended name:
    Glycogen synthase
    EC=2.4.1.21
Alternative name(s):
    Starch [bacterial glycogen] synthase

Gene names

Name:	glgA
Ordered Locus Names:	aq_721

Organism

Aquifex aeolicus [Complete proteome] [HAMAP]

Taxonomic identifier

63363 [NCBI]

Taxonomic lineage

Bacteria › Aquificae › Aquificales › Aquificaceae › Aquifex

Protein attributes

Sequence length	463 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Synthesizes alpha-1,4-glucan chains using ADP-glucose. HAMAP MF_00484
Catalytic activity	ADP-glucose + (1,4-alpha-D-glucosyl)(n) = ADP + (1,4-alpha-D-glucosyl)(n+1). HAMAP MF_00484
Pathway	Glycan biosynthesis; glycogen biosynthesis. HAMAP MF_00484
Sequence similarities	Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.

Ontologies

Keywords
Biological process	Glycogen biosynthesis
Molecular function	Glycosyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycogen biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	starch synthase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 463	463	Glycogen synthase HAMAP MF_00484		PRO_0000188589
Sites
	Binding site	15	1	ADP-glucose By similarity

Sequences

	Sequence		Length	Mass (Da)
	O66935-1 [UniParc]. Last modified August 1, 1998. Version 1. Checksum: D896172D0D3DB27D	FASTA	463	53,457
	10 20 30 40 50 60 MRVLFCSSEI YPYAKTGGLA DFSFCLIKYL KKYGVKVKGV MPYYKTLKAE NLRKTDKGVT 70 80 90 100 110 120 LNLNGKDYTF EVYESEDCYF LRNDELFGRD YIYGPPGWGY EDNDIRFGGF SRAVSELIST 130 140 150 160 170 180 GQLEADVVHA NDWQTALIPL FLKEVFKTPV KTVFTIHNLA YQGLFPKETV ERVGIPPYLF 190 200 210 220 230 240 HMEAVEFWGL VNFMKGGIVF SDLITTVSPT YAKEIQTQEY GYGLEGVLKK YSYKLRGILN 250 260 270 280 290 300 GIDYEVWNPE KDKYIYQNYS LRNYSKKFKN KEFLSKELGI EAEKPLISFI NRFTHQKGVE 310 320 330 340 350 360 LILNCAEEMS KLNANFVFLG TGEYENAFLD VSKIYKNFKV FAEFNEGFAR KLYASSDFIL 370 380 390 400 410 420 MPSYFEPCGL TQMIGMRYGC VPIVRKTGGL RDTVKDISEG GYGITFEEPS KETFLCSLKR 430 440 450 460 AIELYENAKK FRNSVKIVMS LDFSCDRMTK EYIECYEEVQ SHQ

References

[1]

"The complete genome of the hyperthermophilic bacterium Aquifex aeolicus." Deckert G., Warren P.V., Gaasterland T., Young W.G., Lenox A.L., Graham D.E., Overbeek R., Snead M.A., Keller M., Aujay M., Huber R., Feldman R.A., Short J.M., Olsen G.J., Swanson R.V. Nature 392:353-358(1998) [PubMed: 9537320] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: VF5.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE000657 Genomic DNA. Translation: AAC06894.1.
PIR	C70363.
RefSeq	NP_213495.1.
3D structure databases
ModBase	Search...
Protein family/group databases
CAZy	GT5. Glycosyltransferase Family 5.
Genome annotation databases
GeneID	1193384.
GenomeReviews	Gene locus aq_721 in contig AE000657_GR.
KEGG	aae:aq_721.
NMPDR	fig|224324.1.peg.510.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	O66935.
OMA	O66935. LTHIEIV.
Enzyme and pathway databases
BioCyc	AAEO224324:AQ_721-MON.
BRENDA	2.4.1.21. 189781.
Family and domain databases
HAMAP	MF_00484. [Tree]
InterPro	IPR011835. GlgA. IPR001296. Glyco_trans_1. IPR013534. Glyco_transf_5. [Graphical view]
Pfam	PF08323. Glyco_transf_5. 1 hit. PF00534. Glycos_transf_1. 1 hit. [Graphical view]
TIGRFAMs	TIGR02095. glgA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

GLGA_AQUAE

Accession

Primary (citable) accession number: O66935

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 16, 2001
Last sequence update:	August 1, 1998
Last modified:	June 16, 2009
This is version 46 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)