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Protein
Submitted name:

Cation efflux system (AcrB/AcrD/AcrF family)

Gene

acrD1

Organism
Aquifex aeolicus (strain VF5)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

Complete GO annotation...

Enzyme and pathway databases

BioCyciAAEO224324:GJBH-500-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Cation efflux system (AcrB/AcrD/AcrF family)Imported
Gene namesi
Name:acrD1Imported
Ordered Locus Names:aq_695Imported
OrganismiAquifex aeolicus (strain VF5)Imported
Taxonomic identifieri224324 [NCBI]
Taxonomic lineageiBacteriaAquificaeAquificalesAquificaceaeAquifex
Proteomesi
  • UP000000798 Componenti: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei354 – 37320HelicalSequence analysisAdd
BLAST
Transmembranei379 – 39618HelicalSequence analysisAdd
BLAST
Transmembranei408 – 42619HelicalSequence analysisAdd
BLAST
Transmembranei456 – 47722HelicalSequence analysisAdd
BLAST
Transmembranei489 – 50719HelicalSequence analysisAdd
BLAST
Transmembranei545 – 56319HelicalSequence analysisAdd
BLAST
Transmembranei904 – 92320HelicalSequence analysisAdd
BLAST
Transmembranei930 – 95021HelicalSequence analysisAdd
BLAST
Transmembranei956 – 97520HelicalSequence analysisAdd
BLAST
Transmembranei1010 – 103021HelicalSequence analysisAdd
BLAST
Transmembranei1036 – 105823HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Interactioni

Protein-protein interaction databases

STRINGi224324.aq_695.

Structurei

3D structure databases

ProteinModelPortaliO66916.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. [View classification]SAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG4105BZS. Bacteria.
COG0841. LUCA.
HOGENOMiHOG000280649.
InParanoidiO66916.
OMAiRHYNRFR.
OrthoDBiEOG6FZ47N.

Family and domain databases

Gene3Di3.30.2090.10. 2 hits.
InterProiIPR027463. AcrB_DN_DC_subdom.
IPR001036. Acrflvin-R.
[Graphical view]
PfamiPF00873. ACR_tran. 1 hit.
[Graphical view]
PRINTSiPR00702. ACRIFLAVINRP.
SUPFAMiSSF82714. SSF82714. 2 hits.

Sequencei

Sequence statusi: Complete.

O66916-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MYGLAGRLAN FFIDSKLTPI LILVSLALGL FAVLTTPREE EPQIVVPMID
60 70 80 90 100
IFIPYPGATP EEVEARVVFP LEKILWELKD IEYIYSASTN DMGIVTARFY
110 120 130 140 150
VGTDPVKALV DLNSKMMSAL DKAPPGVILP PVVRLMSIDD VPILTLTLWG
160 170 180 190 200
ENYDWYELRR LAATLQNEIK KIENVANVYL IGGRPRQIRI ILDPAKMAAY
210 220 230 240 250
GISPLYIDQL LRSANAQAIS GKINKGNMEY LVKTGPFFKS VRDVENVVVG
260 270 280 290 300
VRNGRVIFLK DVAKIVDGPS EIKDYVFFGI GEAHEYKGIE GKPGELYPAV
310 320 330 340 350
TIAVAKRKGT NAVVVAEQVI EFVESLKGKV IPSDVNITVT RNYGETAQEK
360 370 380 390 400
ALELLEHLFI ATFSVVLLIA VSLGVREAIV VGLAVPVTLS IALFLNEMYG
410 420 430 440 450
FTLNRVTLFA LIFSIGILVD DAIVVVENIH RWFEMQKLPP RDAIVHATDE
460 470 480 490 500
VGNPTILATF TVIAALMPMA FVTGMMGPYM RPIPINASVA MFFSLLVAFI
510 520 530 540 550
VTPWAAYHIL KKEREHEEIN IRKTLFWKLY CHIMYPLLAS KLKRYAFYLF
560 570 580 590 600
VLALMGGSVG LLFTKTVLVK MLPYDNKSEL EIVLDMPEGT TLEDTLKVAK
610 620 630 640 650
EIADYVGRYS IVTDYQIYAG TAAPFTFNGL VRHYYLRQAS NLAEIQVNLV
660 670 680 690 700
GKHDRDLQSH EFAKLIRPKV HEIASKYGAK YVAVVEVPPG PPVLSPIVAE
710 720 730 740 750
VYAPDMKVQR EFAWRVLKIF KDSPAITDEG IYLEYPAPMI RFEVKEDKVK
760 770 780 790 800
LAGLTKQEVV YTLKALIGGW QAGIMQTTDT EHVPIIIRLD EKYRVPELLK
810 820 830 840 850
NVKIPNREGK LIPLSELVEI KEGPIPETIY HKNLRRVIYV IGDVAGREEA
860 870 880 890 900
PIYGILDVRD KILNIENPYG EVGELWMSLP VLEDRVYVKW DGEMHITLEV
910 920 930 940 950
FRDLGLAFAV AVFVMYVLVL GWFKDFRIPG IILAPIPLTL VGIIPGHWLM
960 970 980 990 1000
DKIMGNVFFT ATSMIGFIAL GGIIVRNSIL LVDFAEQRLK EGLPVHVAVV
1010 1020 1030 1040 1050
EAGVIRTRPI LLTAAAVIIG AFVIIFDPIF NGLAISLIFG TIGSTTLTLV
1060 1070 1080
LIPVMYYASK IKRMPPEACP TPEMIKRDLM AD
Length:1,082
Mass (Da):120,761
Last modified:August 1, 1998 - v1
Checksum:i4B9A95D2A180BBF4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000657 Genomic DNA. Translation: AAC06875.1.
PIRiH70360.
RefSeqiNP_213476.1. NC_000918.1.
WP_010880414.1. NC_000918.1.

Genome annotation databases

EnsemblBacteriaiAAC06875; AAC06875; aq_695.
GeneIDi1193978.
KEGGiaae:aq_695.
PATRICi20958854. VBIAquAeo85532_0558.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000657 Genomic DNA. Translation: AAC06875.1.
PIRiH70360.
RefSeqiNP_213476.1. NC_000918.1.
WP_010880414.1. NC_000918.1.

3D structure databases

ProteinModelPortaliO66916.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi224324.aq_695.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC06875; AAC06875; aq_695.
GeneIDi1193978.
KEGGiaae:aq_695.
PATRICi20958854. VBIAquAeo85532_0558.

Phylogenomic databases

eggNOGiENOG4105BZS. Bacteria.
COG0841. LUCA.
HOGENOMiHOG000280649.
InParanoidiO66916.
OMAiRHYNRFR.
OrthoDBiEOG6FZ47N.

Enzyme and pathway databases

BioCyciAAEO224324:GJBH-500-MONOMER.

Family and domain databases

Gene3Di3.30.2090.10. 2 hits.
InterProiIPR027463. AcrB_DN_DC_subdom.
IPR001036. Acrflvin-R.
[Graphical view]
PfamiPF00873. ACR_tran. 1 hit.
[Graphical view]
PRINTSiPR00702. ACRIFLAVINRP.
SUPFAMiSSF82714. SSF82714. 2 hits.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: VF5Imported.

Entry informationi

Entry nameiO66916_AQUAE
AccessioniPrimary (citable) accession number: O66916
Entry historyi
Integrated into UniProtKB/TrEMBL: August 1, 1998
Last sequence update: August 1, 1998
Last modified: May 11, 2016
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.