O66895 (O66895_AQUAE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Hydrogenase large subunit EMBL AAC06861.1

Gene names

Name:	mbhL1 EMBL AAC06861.1
Ordered Locus Names:	aq_662

Organism

Aquifex aeolicus (strain VF5)

Taxonomic identifier

224324 [NCBI]

Taxonomic lineage

Bacteria › Aquificae › Aquificales › Aquificaceae › Aquifex

Protein attributes

Sequence length	633 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. RuleBase RU003896

Ontologies

Keywords
Ligand	Metal-binding RuleBase RU003896 Nickel RuleBase RU003896
Molecular function	Oxidoreductase RuleBase RU003896
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Molecular function	ferredoxin hydrogenase activity Inferred from electronic annotation. Source: InterPro nickel cation binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	O66895 [UniParc]. Last modified August 1, 1998. Version 1. Checksum: A2457F5106BF4E79	FASTA	633	71,965
	10 20 30 40 50 60 MKRVVVDPVT RIEGHLRIEI MVDEETGQVK DALSAGTMWR GIELIVRNRD PRDVWAFTQR 70 80 90 100 110 120 ICGVCTSIHA LASLRAVEDA LEITIPKNAN YIRNIMYGSL QVHDHVVHFY HLHALDWVSP 130 140 150 160 170 180 VEALKADPVA TAALANKILE KYGVLNEFMP DFLGHRAYPK KFPKATPGYF REFQKKIKKL 190 200 210 220 230 240 VESGQLGIFA AHWWDHPDYQ MLPPEVHLIG IAHYLNMLDV QRELFIPQVV FGGKNPHPHY 250 260 270 280 290 300 IVGGVNCSIS MDDMNAPVNA ERLAVVEDAI YTQVESTDFF YIPDILAIAD IYLNQHNWFY 310 320 330 340 350 360 GGGLSKKRVI GYGDYPDEPY TGIKNGDYHK KILWHSNGVV EDFYKGVEKA KFYNLEGKDF 370 380 390 400 410 420 TDPEQIQEFV THSWYKYPDE TKGLHPWDGI TEPNYTGPKE GTKTHWKYLD ENGKYSWIKA 430 440 450 460 470 480 PRWRGKACEV GPLARYIIVY TKVKQGHIKP TWVDELIVNQ IDTVSKILNL PPEKWLPTTV 490 500 510 520 530 540 GRTIARALEA QMSAHTNLYW MKKLYDNIKA GDTSVANMEK WDPSTWPKEA KGVGLTEAPR 550 560 570 580 590 600 GALGHWVIIK DGKVANYQCV VPTTWNGSPK DPKGQHGAFE ESMIDTKVKV PEKPLEVLRG 610 620 630 IHSFDPCLAC STHLYNEKGE EIASVRVQGV VHV

References

[1]	"The complete genome of the hyperthermophilic bacterium Aquifex aeolicus." Deckert G., Warren P.V., Gaasterland T., Young W.G., Lenox A.L., Graham D.E., Overbeek R., Snead M.A., Keller M., Aujay M., Huber R., Feldman R.A., Short J.M., Olsen G.J., Swanson R.V. Nature 392:353-358(1998) [PubMed: 9537320] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: VF5.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE000657 Genomic DNA. Translation: AAC06861.1.
PIR	C70358.
RefSeq	NP_213455.1. NC_000918.1.
3D structure databases
HSSP	HSSP built from PDB template 1E3D based on UniProtKB Q9L868.
ProteinModelPortal	O66895.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1193957.
GenomeReviews	Gene locus aq_662 in contig AE000657_GR.
KEGG	aae:aq_662.
NMPDR	fig|224324.1.peg.470.
PATRIC	20958812. VBIAquAeo85532_0537.
Phylogenomic databases
HOGENOM	HBG733231.
OMA	DGVTEPN.
PhylomeDB	O66895.
ProtClustDB	CLSK2299463.
Family and domain databases
InterPro	IPR001501. Ni-dep_hyd_lsu. IPR018194. Ni-dep_hyd_lsu_Ni_BS. [Graphical view]
KO	K06281.
Pfam	PF00374. NiFeSe_Hases. 2 hits. [Graphical view]
PROSITE	PS00507. NI_HGENASE_L_1. 1 hit. PS00508. NI_HGENASE_L_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

O66895_AQUAE

Accession

Primary (citable) accession number: O66895

Entry history

Integrated into UniProtKB/TrEMBL:	August 1, 1998
Last sequence update:	August 1, 1998
Last modified:	January 25, 2012
This is version 68 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)