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Protein

Flagellar motor switch protein FliG

Gene

fliG

Organism
Aquifex aeolicus (strain VF5)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

FliG is one of 2 proteins (FliG, FliN) that might form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity).By similarity

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sitei162 – 1621Part of the EHPQR-motif

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Chemotaxis, Flagellar rotation

Enzyme and pathway databases

BioCyciAAEO224324:GJBH-474-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Flagellar motor switch protein FliG
Gene namesi
Name:fliG
Ordered Locus Names:aq_653
OrganismiAquifex aeolicus (strain VF5)
Taxonomic identifieri224324 [NCBI]
Taxonomic lineageiBacteriaAquificaeAquificalesAquificaceaeAquifex
Proteomesi
  • UP000000798 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Bacterial flagellum, Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 328328Flagellar motor switch protein FliGPRO_0000184081Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi224324.aq_653.

Structurei

Secondary structure

1
328
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Helixi6 – 2015Combined sources
Helixi23 – 3210Combined sources
Helixi35 – 4612Combined sources
Helixi53 – 6917Combined sources
Helixi77 – 8711Combined sources
Helixi92 – 11322Combined sources
Helixi117 – 1248Combined sources
Helixi129 – 1368Combined sources
Helixi141 – 1499Combined sources
Helixi153 – 16513Combined sources
Helixi171 – 19222Combined sources
Helixi198 – 20811Combined sources
Helixi211 – 22414Combined sources
Helixi226 – 23611Combined sources
Helixi239 – 2446Combined sources
Helixi247 – 2548Combined sources
Helixi259 – 2679Combined sources
Helixi271 – 2788Combined sources
Helixi283 – 29513Combined sources
Helixi301 – 31919Combined sources
Beta strandi321 – 3233Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3HJLX-ray2.40A1-328[»]
ProteinModelPortaliO66891.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiO66891.

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi127 – 1304Part of the EHPQR-motif

Sequence similaritiesi

Belongs to the FliG family.Curated

Phylogenomic databases

eggNOGiENOG4105CS3. Bacteria.
COG1536. LUCA.
HOGENOMiHOG000257646.
InParanoidiO66891.
KOiK02410.
OMAiTLQVRPF.
OrthoDBiEOG683S79.

Family and domain databases

Gene3Di1.10.220.30. 3 hits.
InterProiIPR001810. F-box_dom.
IPR000090. Flg_Motor_Flig.
IPR023087. Flg_Motor_Flig_C.
IPR011002. FliG_a-hlx.
IPR032779. FliG_M.
IPR028263. FliG_N.
[Graphical view]
PANTHERiPTHR30534. PTHR30534. 1 hit.
PfamiPF01706. FliG_C. 1 hit.
PF14841. FliG_M. 1 hit.
PF14842. FliG_N. 1 hit.
[Graphical view]
PIRSFiPIRSF003161. FliG. 1 hit.
PRINTSiPR00954. FLGMOTORFLIG.
SUPFAMiSSF48029. SSF48029. 2 hits.
TIGRFAMsiTIGR00207. fliG. 1 hit.

Sequencei

Sequence statusi: Complete.

O66891-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAQEKSALSK AQKAAVLLLS LPEEVSMNIV KELSEEELQK LFALAKDLES
60 70 80 90 100
VPEEEIENIA EELLDEIKKA GIKIKKPEEF IENIKKVIPP TLAEKFRGIL
110 120 130 140 150
ELGDAEKILK EIEKVDSRIL ASLLKNEHPQ TIALFLSQLS PKKSAEIIQN
160 170 180 190 200
LPEELKKEVV KRIATLENVN VQYVKELAQI LLEEISSLGA KEALKLEGTA
210 220 230 240 250
VAAELLNTLD KETRELILQS IGQEDPLLEE RIREKMFTFE DIRKLSDRDI
260 270 280 290 300
IEILKVVDKN TLMIALLGAP EDIKQKFLSN MSKRAAKLFL EDMEALGPVK
310 320
KSEIEKAQRQ VVNIIRKMID EGKIEIGD
Length:328
Mass (Da):37,032
Last modified:August 1, 1998 - v1
Checksum:i0C5DF04156A2C0F6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000657 Genomic DNA. Translation: AAC06845.1.
PIRiG70357.
RefSeqiNP_213451.1. NC_000918.1.
WP_010880389.1. NC_000918.1.

Genome annotation databases

EnsemblBacteriaiAAC06845; AAC06845; aq_653.
GeneIDi1193953.
KEGGiaae:aq_653.
PATRICi20958800. VBIAquAeo85532_0532.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000657 Genomic DNA. Translation: AAC06845.1.
PIRiG70357.
RefSeqiNP_213451.1. NC_000918.1.
WP_010880389.1. NC_000918.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3HJLX-ray2.40A1-328[»]
ProteinModelPortaliO66891.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi224324.aq_653.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC06845; AAC06845; aq_653.
GeneIDi1193953.
KEGGiaae:aq_653.
PATRICi20958800. VBIAquAeo85532_0532.

Phylogenomic databases

eggNOGiENOG4105CS3. Bacteria.
COG1536. LUCA.
HOGENOMiHOG000257646.
InParanoidiO66891.
KOiK02410.
OMAiTLQVRPF.
OrthoDBiEOG683S79.

Enzyme and pathway databases

BioCyciAAEO224324:GJBH-474-MONOMER.

Miscellaneous databases

EvolutionaryTraceiO66891.

Family and domain databases

Gene3Di1.10.220.30. 3 hits.
InterProiIPR001810. F-box_dom.
IPR000090. Flg_Motor_Flig.
IPR023087. Flg_Motor_Flig_C.
IPR011002. FliG_a-hlx.
IPR032779. FliG_M.
IPR028263. FliG_N.
[Graphical view]
PANTHERiPTHR30534. PTHR30534. 1 hit.
PfamiPF01706. FliG_C. 1 hit.
PF14841. FliG_M. 1 hit.
PF14842. FliG_N. 1 hit.
[Graphical view]
PIRSFiPIRSF003161. FliG. 1 hit.
PRINTSiPR00954. FLGMOTORFLIG.
SUPFAMiSSF48029. SSF48029. 2 hits.
TIGRFAMsiTIGR00207. fliG. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: VF5.
  2. "Structure of the torque ring of the flagellar motor and the molecular basis for rotational switching."
    Lee L.K., Ginsburg M.A., Crovace C., Donohoe M., Stock D.
    Nature 466:996-1000(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.40 ANGSTROMS).

Entry informationi

Entry nameiFLIG_AQUAE
AccessioniPrimary (citable) accession number: O66891
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: August 1, 1998
Last modified: May 11, 2016
This is version 100 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.