O66787 (O66787_AQUAE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Glucose-6-phosphate 1-dehydrogenase RuleBase RU000497
EC=1.1.1.49 RuleBase RU000497

Gene names

Name:	gsdA EMBL AAC06740.1
Ordered Locus Names:	aq_497 EMBL AAC06740.1

Organism

Aquifex aeolicus (strain VF5) [Reference proteome] [HAMAP] EMBL AAC06740.1

Taxonomic identifier

224324 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Aquificae › Aquificae › Aquificales › Aquificaceae › Aquifex › Aquifex aeolicus

Protein attributes

Sequence length	431 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	D-glucose 6-phosphate + NADP+ = D-glucono-1,5-lactone 6-phosphate + NADPH. RuleBase RU000497
Pathway	Carbohydrate degradation; pentose phosphate pathway. RuleBase RU000497
Sequence similarities	Belongs to the glucose-6-phosphate dehydrogenase family. RuleBase RU000497

Ontologies

Keywords
Biological process	Carbohydrate metabolism Glucose metabolism RuleBase RU000497
Ligand	NADP RuleBase RU000497
Molecular function	Oxidoreductase RuleBase RU000497
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	pentose-phosphate shunt Inferred from electronic annotation. Source: UniProtKB-UniPathway
Molecular_function	NADP binding Inferred from electronic annotation. Source: InterPro glucose-6-phosphate dehydrogenase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	O66787 [UniParc]. Last modified August 1, 1998. Version 1. Checksum: 371B8E4ABEE03658	FASTA	431	50,232
	10 20 30 40 50 60 MSSGDTELRK RIEFIIFGGT GDLSRNKLIP AILKLKDKID LKKIYILGRN RKKFEEIKEK 70 80 90 100 110 120 FKDFSELFVF VEFLAEREES YKNISSILGK ESLKVFYLAV PPDLFKEILE NVGKYLNFPE 130 140 150 160 170 180 KRIVIEKPFG LSLKHAKDLN KIISVYFKEE EIFRIDHYLG KPQVQNILAF KFSNYVFSEV 190 200 210 220 230 240 LNKCLVEKVE VIALEEVGVE GRKAYYEKVG VIRDMLQNHM LLLSSLIVMR LPPRAEDFHF 250 260 270 280 290 300 ELKNALKRAE FESESLILGK YKSYQGKAPT FALVKLHFDD ERFTGVPFVL ATGKKLKKKL 310 320 330 340 350 360 TRVCIHFKNF PKEIERLLGC VPERNLLVFE LYPEQEVSFR VNVISPLGFL RCTESINWRV 370 380 390 400 410 420 SLKDVLGEIP EAYESLLLDV IRGDKTLFLD AEETEILWEK TEPLLKKEKE VLTYDDRVLI 430 PEFAEDFISC L

References

[1]

"The complete genome of the hyperthermophilic bacterium Aquifex aeolicus." Deckert G., Warren P.V., Gaasterland T., Young W.G., Lenox A.L., Graham D.E., Overbeek R., Snead M.A., Keller M., Aujay M., Huber R., Feldman R.A., Short J.M., Olsen G.J., Swanson R.V. Nature 392:353-358(1998) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: VF5 EMBL AAC06740.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE000657 Genomic DNA. Translation: AAC06740.1.
PIR	G70344.
RefSeq	NP_213347.1. NC_000918.1.
3D structure databases
ProteinModelPortal	O66787.
ModBase	Search...
Protein-protein interaction databases
STRING	224324.aq_497.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAC06740; AAC06740; aq_497.
GeneID	1193205.
KEGG	aae:aq_497.
PATRIC	20958546. VBIAquAeo85532_0408.
Phylogenomic databases
HOGENOM	HOG000046192.
KO	K00036.
OMA	FANQMFE.
ProtClustDB	PRK05722.
Enzyme and pathway databases
BioCyc	AAEO224324:GJBH-367-MONOMER.
UniPathway	UPA00115.
Family and domain databases
Gene3D	3.40.50.720. 1 hit.
InterPro	IPR001282. G6P_DH. IPR022675. G6P_DH_C. IPR022674. G6P_DH_NAD-bd. IPR016040. NAD(P)-bd_dom. [Graphical view]
PANTHER	PTHR23429. PTHR23429. 1 hit.
Pfam	PF02781. G6PD_C. 1 hit. PF00479. G6PD_N. 1 hit. [Graphical view]
PIRSF	PIRSF000110. G6PD. 1 hit.
PRINTS	PR00079. G6PDHDRGNASE.
ProtoNet	Search...

Entry information

Entry name

O66787_AQUAE

Accession

Primary (citable) accession number: O66787
Secondary accession number(s): Q79LP1

Entry history

Integrated into UniProtKB/TrEMBL:	August 1, 1998
Last sequence update:	August 1, 1998
Last modified:	May 29, 2013
This is version 89 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)