SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

O66787

- O66787_AQUAE

UniProt

O66787 - O66787_AQUAE

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Glucose-6-phosphate 1-dehydrogenase

Gene
gsdA, zwf, aq_497
Organism
Aquifex aeolicus (strain VF5)
Status
Unreviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone By similarity.UniRule annotation

Catalytic activityi

D-glucose 6-phosphate + NADP+ = 6-phospho-D-glucono-1,5-lactone + NADPH.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei51 – 511NADP By similarityUniRule annotation
Binding sitei127 – 1271NADP By similarityUniRule annotation
Binding sitei157 – 1571Substrate By similarityUniRule annotation
Binding sitei161 – 1611Substrate By similarityUniRule annotation
Binding sitei195 – 1951Substrate By similarityUniRule annotation
Binding sitei214 – 2141Substrate By similarityUniRule annotation
Active sitei219 – 2191Proton acceptor By similarityUniRule annotation
Binding sitei294 – 2941Substrate By similarityUniRule annotation
Binding sitei299 – 2991Substrate By similarityUniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi18 – 258NADP By similarityUniRule annotation

GO - Molecular functioni

  1. glucose-6-phosphate dehydrogenase activity Source: UniProtKB-HAMAP
  2. NADP binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. pentose-phosphate shunt Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotation

Keywords - Biological processi

Carbohydrate metabolism, Glucose metabolismUniRule annotation

Keywords - Ligandi

NADPUniRule annotation

Enzyme and pathway databases

BioCyciAAEO224324:GJBH-367-MONOMER.
UniPathwayiUPA00115; UER00408.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate 1-dehydrogenaseUniRule annotation (EC:1.1.1.49UniRule annotation)
Short name:
G6PDUniRule annotation
Gene namesi
Name:gsdAImported
Synonyms:zwfUniRule annotation
Ordered Locus Names:aq_497Imported
OrganismiAquifex aeolicus (strain VF5)Imported
Taxonomic identifieri224324 [NCBI]
Taxonomic lineageiBacteriaAquificaeAquificalesAquificaceaeAquifex
ProteomesiUP000000798: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi224324.aq_497.

Structurei

3D structure databases

ProteinModelPortaliO66787.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

HOGENOMiHOG000046192.
KOiK00036.
OMAiWRWVEPL.
OrthoDBiEOG61308Z.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
HAMAPiMF_00966. G6PD.
InterProiIPR001282. G6P_DH.
IPR022675. G6P_DH_C.
IPR022674. G6P_DH_NAD-bd.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PANTHERiPTHR23429. PTHR23429. 1 hit.
PfamiPF02781. G6PD_C. 1 hit.
PF00479. G6PD_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000110. G6PD. 1 hit.
PRINTSiPR00079. G6PDHDRGNASE.

Sequencei

Sequence statusi: Complete.

O66787-1 [UniParc]FASTAAdd to Basket

« Hide

MSSGDTELRK RIEFIIFGGT GDLSRNKLIP AILKLKDKID LKKIYILGRN    50
RKKFEEIKEK FKDFSELFVF VEFLAEREES YKNISSILGK ESLKVFYLAV 100
PPDLFKEILE NVGKYLNFPE KRIVIEKPFG LSLKHAKDLN KIISVYFKEE 150
EIFRIDHYLG KPQVQNILAF KFSNYVFSEV LNKCLVEKVE VIALEEVGVE 200
GRKAYYEKVG VIRDMLQNHM LLLSSLIVMR LPPRAEDFHF ELKNALKRAE 250
FESESLILGK YKSYQGKAPT FALVKLHFDD ERFTGVPFVL ATGKKLKKKL 300
TRVCIHFKNF PKEIERLLGC VPERNLLVFE LYPEQEVSFR VNVISPLGFL 350
RCTESINWRV SLKDVLGEIP EAYESLLLDV IRGDKTLFLD AEETEILWEK 400
TEPLLKKEKE VLTYDDRVLI PEFAEDFISC L 431
Length:431
Mass (Da):50,232
Last modified:August 1, 1998 - v1
Checksum:i371B8E4ABEE03658
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE000657 Genomic DNA. Translation: AAC06740.1.
PIRiG70344.
RefSeqiNP_213347.1. NC_000918.1.

Genome annotation databases

EnsemblBacteriaiAAC06740; AAC06740; aq_497.
GeneIDi1193205.
KEGGiaae:aq_497.
PATRICi20958546. VBIAquAeo85532_0408.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE000657 Genomic DNA. Translation: AAC06740.1 .
PIRi G70344.
RefSeqi NP_213347.1. NC_000918.1.

3D structure databases

ProteinModelPortali O66787.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 224324.aq_497.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAC06740 ; AAC06740 ; aq_497 .
GeneIDi 1193205.
KEGGi aae:aq_497.
PATRICi 20958546. VBIAquAeo85532_0408.

Phylogenomic databases

HOGENOMi HOG000046192.
KOi K00036.
OMAi WRWVEPL.
OrthoDBi EOG61308Z.

Enzyme and pathway databases

UniPathwayi UPA00115 ; UER00408 .
BioCyci AAEO224324:GJBH-367-MONOMER.

Family and domain databases

Gene3Di 3.40.50.720. 1 hit.
HAMAPi MF_00966. G6PD.
InterProi IPR001282. G6P_DH.
IPR022675. G6P_DH_C.
IPR022674. G6P_DH_NAD-bd.
IPR016040. NAD(P)-bd_dom.
[Graphical view ]
PANTHERi PTHR23429. PTHR23429. 1 hit.
Pfami PF02781. G6PD_C. 1 hit.
PF00479. G6PD_N. 1 hit.
[Graphical view ]
PIRSFi PIRSF000110. G6PD. 1 hit.
PRINTSi PR00079. G6PDHDRGNASE.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: VF5Imported.

Entry informationi

Entry nameiO66787_AQUAE
AccessioniPrimary (citable) accession number: O66787
Secondary accession number(s): Q79LP1
Entry historyi
Integrated into UniProtKB/TrEMBL: August 1, 1998
Last sequence update: August 1, 1998
Last modified: July 9, 2014
This is version 96 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

Similar proteinsi