O66740 (O66740_AQUAE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Threonine synthase EMBL AAC06690.1

Gene names

Name:	thrC2 EMBL AAC06690.1
Ordered Locus Names:	aq_425

Organism

Aquifex aeolicus (strain VF5)

Taxonomic identifier

224324 [NCBI]

Taxonomic lineage

Bacteria › Aquificae › Aquificales › Aquificaceae › Aquifex

Protein attributes

Sequence length	352 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

Ontologies

Keywords
Ligand	Pyridoxal phosphate PDB 2ZSJ
Technical term	3D-structure PDB 2ZSJ Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	threonine biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	pyridoxal phosphate binding Inferred from electronic annotation. Source: InterPro threonine synthase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Amino acid modifications
	Modified residue	63	1	Pyridoxal phosphate PDB 2ZSJ

Sequences

	Sequence		Length	Mass (Da)
	O66740 [UniParc]. Last modified August 1, 1998. Version 1. Checksum: 3BF480E6E097ACD2	FASTA	352	37,809
	10 20 30 40 50 60 MNRWQGIIKQ YKKYLPVDEN TPIVTLYEGN TPLIEADNLA RAIGFKGKIY LKYEGLNPTG 70 80 90 100 110 120 SFKDRGMTLA ISKAVEAGKR AVICASTGNT SASAAAYAAR AGLRAYVLLP KGAVAIGKLS 130 140 150 160 170 180 QAMIYGAKVL AIQGTFDDAL NIVRKIGENF PVEIVNSVNP YRIEGQKTAA FEICDTLGEA 190 200 210 220 230 240 PDYHFIPVGN AGNITAYWKG FKIYYEEGKI TKLPRMMGWQ AEGAAPIVKG YPIKNPQTIA 250 260 270 280 290 300 TAIKIGNPYS WKSALKAAQE SGGKIDAVSD SEILYAYKLI ASTEGVFCEP ASAASVAGLI 310 320 330 340 350 KLVREGFFKG GEVVTCTLTG NGLKDPDTAI KVCEEPITVP PDFDEVVKVL GF

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The complete genome of the hyperthermophilic bacterium Aquifex aeolicus." Deckert G., Warren P.V., Gaasterland T., Young W.G., Lenox A.L., Graham D.E., Overbeek R., Snead M.A., Keller M., Aujay M., Huber R., Feldman R.A., Short J.M., Olsen G.J., Swanson R.V. Nature 392:353-358(1998) [PubMed: 9537320] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: VF5.
[2]	"Crystal structure of threonine synthase from Aquifex aeolicus VF5." Mizutani H., Kunishima N. Submitted (SEP-2008) to the PDB data bank Cited for: X-RAY CRYSTALLOGRAPHY (1.80 ANGSTROMS), PYRIDOXAL PHOSPHATE AT LYS-63.
+	Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

AE000657 Genomic DNA. Translation: AAC06690.1.

PIR

H70338.

RefSeq

NP_213300.1. NC_000918.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
2ZSJ	X-ray	1.80	A/B/C/D	1-352	[»]

ProteinModelPortal

O66740.

SMR

O66740. Positions 4-331.

ModBase

Search...

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Genome annotation databases

GeneID

1193066.

GenomeReviews

Gene locus aq_425 in contig AE000657_GR.

KEGG

aae:aq_425.

NMPDR

fig|224324.1.peg.315.

PATRIC

20958430. VBIAquAeo85532_0351.

Phylogenomic databases

HOGENOM

HBG694883.

OMA

GTPLYKC.

PhylomeDB

O66740.

ProtClustDB

PRK07409.

Family and domain databases

InterPro

IPR001926. PyrdxlP-dep_enz_bsu.
IPR000634. Ser/Thr_deHydtase_PyrdxlP-BS.
IPR004450. Thr_synthase.
[Graphical view]

KO

K01733.

Pfam

PF00291. PALP. 1 hit.
[Graphical view]

SUPFAM

SSF53686. PyrdxlP-dep_enz_bsu. 1 hit.

TIGRFAMs

TIGR00260. ThrC. 1 hit.

PROSITE

PS00165. DEHYDRATASE_SER_THR. 1 hit.
[Graphical view]

ProtoNet

Search...

Entry information

Entry name

O66740_AQUAE

Accession

Primary (citable) accession number: O66740

Entry history

Integrated into UniProtKB/TrEMBL:	August 1, 1998
Last sequence update:	August 1, 1998
Last modified:	January 25, 2012
This is version 66 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)