true2000-12-012024-03-27119OGG1_AQUAEThe complete genome of the hyperthermophilic bacterium Aquifex aeolicus.Deckert G.Warren P.V.Gaasterland T.Young W.G.Lenox A.L.Graham D.E.Overbeek R.Snead M.A.Keller M.Aujay M.Huber R.Feldman R.A.Short J.M.Olsen G.J.Swanson R.V.doi:10.1038/328311998Nature392353-358NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]VF5BacteriaENDO3cHelix-hairpin-Helix base-excision DNA repair enzymes (C-terminal)OggDNA_glyclase/AP_lyase_OggDNA_glycosylaseHhH-GPD_domainHhH_base_excis_CThrmst_oggENDO3cDNA-glycosylase8-oxoguanine DNA glycosylase/AP lyase8-oxoguanine DNA glycosylase8-oxoG DNA glycosylase3.2.2.-DNA-(apurinic or apyrimidinic site) lyaseAP lyase4.2.99.18oggaq_251Catalyzes the excision of an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine = 8-oxoG) from DNA. Also cleaves the DNA backbone at apurinic/apyrimidinic sites (AP sites).Belongs to the type-2 OGG1 family.8-oxoguanine DNA glycosylase/AP lyase263061226149167Important for guanine/8-oxoguanine distinction1998-08-01126306d6efd4dd5e0f9947432bde437471aa7dMDAIQEVKRIIPEVQKYVNQRMEEFERLGREGWTHFDFRPFLDIDYDAGLFSELSFCILTANSSATLGIKIQAHLGEEGFLNKTKEELEEVFRKFGHRYAGQRAERIVEAREKFPKVKSLIEKEKNSKVIRELLADPKSPYKIKGFGYKEASHFLRNIGFKDLAIIDRHISRFLMEKGLLRQVKSITPKVYLEAEKALESLAKELGLSLGELDLYIFYIKTKKVLKtruetrue