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Protein
Submitted name:

Histidine kinase sensor protein

Gene

hksP4

Organism
Aquifex aeolicus (strain VF5)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

Catalytic activityi

ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.SAAS annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

KinaseSAAS annotationImported, Transferase

Keywords - Ligandi

ATP-bindingSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciAAEO224324:GJBH-172-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Histidine kinase sensor proteinImported
Gene namesi
Name:hksP4Imported
Ordered Locus Names:aq_231Imported
OrganismiAquifex aeolicus (strain VF5)Imported
Taxonomic identifieri224324 [NCBI]
Taxonomic lineageiBacteriaAquificaeAquificalesAquificaceaeAquifex
Proteomesi
  • UP000000798 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Interactioni

Protein-protein interaction databases

STRINGi224324.aq_231.

Structurei

3D structure databases

ProteinModelPortaliO66597.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini138 – 339202Histidine kinaseInterPro annotationAdd
BLAST

Phylogenomic databases

eggNOGiENOG4105BZU. Bacteria.
COG0642. LUCA.
COG2202. LUCA.
HOGENOMiHOG000115025.
InParanoidiO66597.
KOiK02482.
OMAiCDGECHP.
OrthoDBiPOG091H053D.

Family and domain databases

Gene3Di1.10.287.130. 1 hit.
3.30.565.10. 1 hit.
InterProiIPR003594. HATPase_C.
IPR005467. His_kinase_dom.
IPR003661. HisK_dim/P.
IPR000014. PAS.
IPR004358. Sig_transdc_His_kin-like_C.
[Graphical view]
PfamiPF02518. HATPase_c. 1 hit.
PF00512. HisKA. 1 hit.
PF13426. PAS_9. 1 hit.
[Graphical view]
PRINTSiPR00344. BCTRLSENSOR.
SMARTiSM00387. HATPase_c. 1 hit.
SM00388. HisKA. 1 hit.
[Graphical view]
SUPFAMiSSF47384. SSF47384. 1 hit.
SSF55785. SSF55785. 1 hit.
SSF55874. SSF55874. 1 hit.
PROSITEiPS50109. HIS_KIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O66597-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGEFEVFEKF KEQVVVIDKD YKIVYANESY VKENGYRSKE EVVGKPCYLV
60 70 80 90 100
SHKRDEPCDG ECHPCPLKEI QKRKGAVSVV HTHYTHDNKE VHVEICAFPI
110 120 130 140 150
EEGRKIIQFI KNIKNDKEKF YLFSLSQKLS SVGYLALGVA HQLNTPLATI
160 170 180 190 200
SLALEELEKK CGSCEEIEVI KNALISCKNT VDKLLLFARK DNNKDLVDTK
210 220 230 240 250
KAVEDVLELL RVYAKERGVI IEKELESVYM FGNETDIRHV VLNLVLNAIQ
260 270 280 290 300
ASDRGKKVRV FLKKEGEELI LIVEDEGKGI PPEEVDKIFL PFYHGKDKRE
310 320 330
GSGLGLAIVN DIVKSYGGKI NLRSAPGKGS IFEVHLPLS
Length:339
Mass (Da):38,348
Last modified:August 1, 1998 - v1
Checksum:iD88FD7D86EC0FA44
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000657 Genomic DNA. Translation: AAC06560.1.
PIRiA70321.
RefSeqiNP_213157.1. NC_000918.1.
WP_010880095.1. NC_000918.1.

Genome annotation databases

EnsemblBacteriaiAAC06560; AAC06560; aq_231.
GeneIDi1192831.
KEGGiaae:aq_231.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000657 Genomic DNA. Translation: AAC06560.1.
PIRiA70321.
RefSeqiNP_213157.1. NC_000918.1.
WP_010880095.1. NC_000918.1.

3D structure databases

ProteinModelPortaliO66597.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi224324.aq_231.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC06560; AAC06560; aq_231.
GeneIDi1192831.
KEGGiaae:aq_231.

Phylogenomic databases

eggNOGiENOG4105BZU. Bacteria.
COG0642. LUCA.
COG2202. LUCA.
HOGENOMiHOG000115025.
InParanoidiO66597.
KOiK02482.
OMAiCDGECHP.
OrthoDBiPOG091H053D.

Enzyme and pathway databases

BioCyciAAEO224324:GJBH-172-MONOMER.

Family and domain databases

Gene3Di1.10.287.130. 1 hit.
3.30.565.10. 1 hit.
InterProiIPR003594. HATPase_C.
IPR005467. His_kinase_dom.
IPR003661. HisK_dim/P.
IPR000014. PAS.
IPR004358. Sig_transdc_His_kin-like_C.
[Graphical view]
PfamiPF02518. HATPase_c. 1 hit.
PF00512. HisKA. 1 hit.
PF13426. PAS_9. 1 hit.
[Graphical view]
PRINTSiPR00344. BCTRLSENSOR.
SMARTiSM00387. HATPase_c. 1 hit.
SM00388. HisKA. 1 hit.
[Graphical view]
SUPFAMiSSF47384. SSF47384. 1 hit.
SSF55785. SSF55785. 1 hit.
SSF55874. SSF55874. 1 hit.
PROSITEiPS50109. HIS_KIN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiO66597_AQUAE
AccessioniPrimary (citable) accession number: O66597
Entry historyi
Integrated into UniProtKB/TrEMBL: August 1, 1998
Last sequence update: August 1, 1998
Last modified: September 7, 2016
This is version 115 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.