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Protein

Cyanate hydratase

Gene

cynS

Organism
Aquifex aeolicus (strain VF5)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide.UniRule annotation

Catalytic activityi

Cyanate + HCO3- + 2 H+ = NH3 + 2 CO2.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei90 – 901UniRule annotation
Active sitei93 – 931UniRule annotation
Active sitei116 – 1161UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Lyase

Enzyme and pathway databases

BioCyciAAEO224324:GJBH-162-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Cyanate hydrataseUniRule annotation (EC:4.2.1.104UniRule annotation)
Short name:
CyanaseUniRule annotation
Alternative name(s):
Cyanate hydrolaseUniRule annotation
Cyanate lyaseUniRule annotation
Gene namesi
Name:cynSUniRule annotation
Ordered Locus Names:aq_212
OrganismiAquifex aeolicus (strain VF5)
Taxonomic identifieri224324 [NCBI]
Taxonomic lineageiBacteriaAquificaeAquificalesAquificaceaeAquifex
Proteomesi
  • UP000000798 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 149149Cyanate hydratasePRO_0000187521Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi224324.aq_212.

Structurei

3D structure databases

ProteinModelPortaliO66587.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the cyanase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108V7B. Bacteria.
COG1513. LUCA.
HOGENOMiHOG000043436.
InParanoidiO66587.
KOiK01725.
OMAiFPDRGRA.
OrthoDBiEOG63FW2F.

Family and domain databases

Gene3Di1.10.260.40. 1 hit.
3.30.1160.10. 1 hit.
HAMAPiMF_00535. Cyanate_hydrat.
InterProiIPR001387. Cro/C1-type_HTH.
IPR008076. Cyanase.
IPR003712. Cyanate_lyase_C.
IPR010982. Lambda_DNA-bd_dom.
[Graphical view]
PfamiPF02560. Cyanate_lyase. 1 hit.
PF01381. HTH_3. 1 hit.
[Graphical view]
PIRSFiPIRSF001263. Cyanate_hydratas. 1 hit.
PRINTSiPR01693. CYANASE.
SMARTiSM01116. Cyanate_lyase. 1 hit.
SM00530. HTH_XRE. 1 hit.
[Graphical view]
SUPFAMiSSF47413. SSF47413. 1 hit.
SSF55234. SSF55234. 1 hit.
TIGRFAMsiTIGR00673. cynS. 1 hit.

Sequencei

Sequence statusi: Complete.

O66587-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRSDIGRLSK YLIERKKNLG LTWEDVSRKL GKSPVYCAML FYGYAQADDE
60 70 80 90 100
EVKAVAELLN LEEKELAELK DAPYREPQQP VPPTDPFVYR LYEVVILYGP
110 120 130 140
ALKDVAHEMF GDGIMSAIDM SVELEKVEQE GAERMVLTFN GKWLKYRKF
Length:149
Mass (Da):17,201
Last modified:August 1, 1998 - v1
Checksum:i0E6F5F4FCF340A5C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000657 Genomic DNA. Translation: AAC06548.1.
PIRiG70319.
RefSeqiNP_213147.1. NC_000918.1.
WP_010880085.1. NC_000918.1.

Genome annotation databases

EnsemblBacteriaiAAC06548; AAC06548; aq_212.
GeneIDi1192821.
KEGGiaae:aq_212.
PATRICi20958076. VBIAquAeo85532_0178.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000657 Genomic DNA. Translation: AAC06548.1.
PIRiG70319.
RefSeqiNP_213147.1. NC_000918.1.
WP_010880085.1. NC_000918.1.

3D structure databases

ProteinModelPortaliO66587.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi224324.aq_212.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC06548; AAC06548; aq_212.
GeneIDi1192821.
KEGGiaae:aq_212.
PATRICi20958076. VBIAquAeo85532_0178.

Phylogenomic databases

eggNOGiENOG4108V7B. Bacteria.
COG1513. LUCA.
HOGENOMiHOG000043436.
InParanoidiO66587.
KOiK01725.
OMAiFPDRGRA.
OrthoDBiEOG63FW2F.

Enzyme and pathway databases

BioCyciAAEO224324:GJBH-162-MONOMER.

Family and domain databases

Gene3Di1.10.260.40. 1 hit.
3.30.1160.10. 1 hit.
HAMAPiMF_00535. Cyanate_hydrat.
InterProiIPR001387. Cro/C1-type_HTH.
IPR008076. Cyanase.
IPR003712. Cyanate_lyase_C.
IPR010982. Lambda_DNA-bd_dom.
[Graphical view]
PfamiPF02560. Cyanate_lyase. 1 hit.
PF01381. HTH_3. 1 hit.
[Graphical view]
PIRSFiPIRSF001263. Cyanate_hydratas. 1 hit.
PRINTSiPR01693. CYANASE.
SMARTiSM01116. Cyanate_lyase. 1 hit.
SM00530. HTH_XRE. 1 hit.
[Graphical view]
SUPFAMiSSF47413. SSF47413. 1 hit.
SSF55234. SSF55234. 1 hit.
TIGRFAMsiTIGR00673. cynS. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: VF5.

Entry informationi

Entry nameiCYNS_AQUAE
AccessioniPrimary (citable) accession number: O66587
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 31, 2002
Last sequence update: August 1, 1998
Last modified: May 11, 2016
This is version 89 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.