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Protein
Submitted name:

Nitrite reductase (NAD(P)H) large subunit

Gene

nirB

Organism
Aquifex aeolicus (strain VF5)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Ligandi

4Fe-4SSAAS annotation, Iron, Iron-sulfur, Metal-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Nitrite reductase (NAD(P)H) large subunitImported
Gene namesi
Name:nirBImported
Ordered Locus Names:aq_206Imported
OrganismiAquifex aeolicus (strain VF5)Imported
Taxonomic identifieri224324 [NCBI]
Taxonomic lineageiBacteriaAquificaeAquificalesAquificaceaeAquifex
Proteomesi
  • UP000000798 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi224324.aq_206.

Structurei

3D structure databases

ProteinModelPortaliO66583.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 280FAD/NAD-binding_domInterPro annotationAdd BLAST280
Domaini414 – 462Fer2_BFDInterPro annotationAdd BLAST49
Domaini523 – 587NIR_SIR_ferrInterPro annotationAdd BLAST65
Domaini597 – 750NIR_SIRInterPro annotationAdd BLAST154
Domaini773 – 830NIR_SIR_ferrInterPro annotationAdd BLAST58
Domaini875 – 983NIR_SIRInterPro annotationAdd BLAST109

Phylogenomic databases

eggNOGiENOG4107QZF. Bacteria.
COG0155. LUCA.
COG1251. LUCA.
HOGENOMiHOG000115024.
InParanoidiO66583.
KOiK00362.
OMAiCFYLAKK.
OrthoDBiPOG091H0PCN.

Family and domain databases

Gene3Di3.50.50.60. 2 hits.
3.90.480.10. 2 hits.
InterProiIPR007419. BFD-like_2Fe2S-bd_dom.
IPR023753. FAD/NAD-binding_dom.
IPR005117. NiRdtase/SiRdtase_haem-b_fer.
IPR006067. NO2/SO3_Rdtase_4Fe4S_dom.
[Graphical view]
PfamiPF04324. Fer2_BFD. 1 hit.
PF01077. NIR_SIR. 2 hits.
PF03460. NIR_SIR_ferr. 2 hits.
PF07992. Pyr_redox_2. 1 hit.
[Graphical view]
SUPFAMiSSF51905. SSF51905. 2 hits.
SSF55124. SSF55124. 2 hits.

Sequencei

Sequence statusi: Complete.

O66583-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKVVIVGNGI AGTALVEEIL RLSSGKDIRI QVFGDEKFIG YNRVLITEVL
60 70 80 90 100
AGRKTLSEIY IKRWQWYEEK GVRLEIGKKV ERLFPNKKIL VTKDGEFYRY
110 120 130 140 150
DKAIIATGSK PFIPPSIKGV NKKGVFTYRT AKDVFEILDY ARVSKRAVVI
160 170 180 190 200
GGGLLGIEVT KALRDIGLEV FLVHILDTLM EQQLDKTASE LLRKDLEDMG
210 220 230 240 250
IKVLLKKVTE EILGEKKAEG VRFSDGDELL ADFVIIATGI RPNVEVGVNS
260 270 280 290 300
GLKVNKGIVV NDYLETSASD IYAVGECIEH RGKTYGLVAP IMEQVKVCAH
310 320 330 340 350
NVVHGNEKKY TGSLTYAMLK VAGVNLFSAG EINEKDGDEV VAFLDNGRSL
360 370 380 390 400
YRKAVIRNNK IVGTILYGDV RGNNYLLDLI KSGKDISEER PYFLIKHILP
410 420 430 440 450
KGTTGVEELK DNDIVCNCNA VTKGEIVKCI KEGCKTLEEI QERTKASTSC
460 470 480 490 500
GSCIELVEEI LKHYVKEKPK RVNKIEVIKK ELHPFDLEFK KRLEKYFSEG
510 520 530 540 550
ELENIPEEDR DVRLKWYGIF YRKATPGYFM VRIRVPNGRL SYEQAKVVSH
560 570 580 590 600
ISEKFCRGEV EITSRQQLQI RWIKLKDLPE ILEALNRVGL STLQTGMDNV
610 620 630 640 650
RNVTGDPLTG LAEDSLIDTL RLSQEITNIF LGKKKYADLP RKLNVAVLGS
660 670 680 690 700
QTDCINALFN DVCFYLSEKD GKLGFNLYLG GKIGSGGPKK AIDMDMFVEP
710 720 730 740 750
YEVPEVFKAT LDIYSTFGNR ENRSKNRLYF LLQEWGVERF REELEKRLYK
760 770 780 790 800
AIPSKGKDLV NKTGEREGII NLRNGTYAVC VVVPAGKIKA KDFRQIAELA
810 820 830 840 850
RKYGSRELRL SVYQNIYIPN IPEENLNPLL GEEIFEKFST VSSPFTMHLI
860 870 880 890 900
ACAGSDTCSF GVIPNKSDAV RVAKYLSERL KLDIPVRMHW SACAKGCGQH
910 920 930 940 950
GSGDIGFVGT KTKLNGKAVL AVDVFVGGSP TKEGFKVIQG LPLDKVEEAS
960 970 980 990 1000
YLLLNYYLEN RLEGESFADF AHRVGVDKLK VVLTSLLQEG ECKLLKPESI

SK
Length:1,002
Mass (Da):112,414
Last modified:August 1, 1998 - v1
Checksum:i93FE6EE7AB2B78AC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000657 Genomic DNA. Translation: AAC06543.1.
PIRiC70319.
RefSeqiNP_213143.1. NC_000918.1.
WP_010880081.1. NC_000918.1.

Genome annotation databases

EnsemblBacteriaiAAC06543; AAC06543; aq_206.
GeneIDi1192725.
KEGGiaae:aq_206.
PATRICi20958068. VBIAquAeo85532_0174.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000657 Genomic DNA. Translation: AAC06543.1.
PIRiC70319.
RefSeqiNP_213143.1. NC_000918.1.
WP_010880081.1. NC_000918.1.

3D structure databases

ProteinModelPortaliO66583.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi224324.aq_206.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC06543; AAC06543; aq_206.
GeneIDi1192725.
KEGGiaae:aq_206.
PATRICi20958068. VBIAquAeo85532_0174.

Phylogenomic databases

eggNOGiENOG4107QZF. Bacteria.
COG0155. LUCA.
COG1251. LUCA.
HOGENOMiHOG000115024.
InParanoidiO66583.
KOiK00362.
OMAiCFYLAKK.
OrthoDBiPOG091H0PCN.

Family and domain databases

Gene3Di3.50.50.60. 2 hits.
3.90.480.10. 2 hits.
InterProiIPR007419. BFD-like_2Fe2S-bd_dom.
IPR023753. FAD/NAD-binding_dom.
IPR005117. NiRdtase/SiRdtase_haem-b_fer.
IPR006067. NO2/SO3_Rdtase_4Fe4S_dom.
[Graphical view]
PfamiPF04324. Fer2_BFD. 1 hit.
PF01077. NIR_SIR. 2 hits.
PF03460. NIR_SIR_ferr. 2 hits.
PF07992. Pyr_redox_2. 1 hit.
[Graphical view]
SUPFAMiSSF51905. SSF51905. 2 hits.
SSF55124. SSF55124. 2 hits.
ProtoNetiSearch...

Entry informationi

Entry nameiO66583_AQUAE
AccessioniPrimary (citable) accession number: O66583
Entry historyi
Integrated into UniProtKB/TrEMBL: August 1, 1998
Last sequence update: August 1, 1998
Last modified: November 30, 2016
This is version 119 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.