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Protein
Submitted name:

AP4A hydrolase

Gene

apfA

Organism
Aquifex aeolicus (strain VF5)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei6ATPCombined sources1
Binding sitei31ATPCombined sources1
Binding sitei67ATPCombined sources1
Binding sitei78ATPCombined sources1
Binding sitei115ATPCombined sources1

GO - Molecular functioni

Keywordsi

Molecular functionHydrolaseUniRule annotationSAAS annotationImported
LigandATP-bindingCombined sources, Nucleotide-binding

Enzyme and pathway databases

BRENDAi3.6.1.17. 396.

Names & Taxonomyi

Protein namesi
Submitted name:
AP4A hydrolaseImported
Gene namesi
Name:apfAImported
Ordered Locus Names:aq_158Imported
OrganismiAquifex aeolicus (strain VF5)Imported
Taxonomic identifieri224324 [NCBI]
Taxonomic lineageiBacteriaAquificaeAquificalesAquificaceaeAquifex
Proteomesi
  • UP000000798 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi224324.aq_158.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3I7UX-ray1.80A/B/C/D1-134[»]
3I7VX-ray1.95A/B1-134[»]
ProteinModelPortaliO66548.
SMRiO66548.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiO66548.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini2 – 127Nudix hydrolaseInterPro annotationAdd BLAST126

Sequence similaritiesi

Belongs to the Nudix hydrolase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108WNV. Bacteria.
COG0494. LUCA.
HOGENOMiHOG000261976.
InParanoidiO66548.
KOiK03574.
OMAiNDPDHEA.
OrthoDBiPOG091H049J.

Family and domain databases

InterProiView protein in InterPro
IPR020476. Nudix_hydrolase.
IPR020084. NUDIX_hydrolase_CS.
IPR000086. NUDIX_hydrolase_dom.
IPR015797. NUDIX_hydrolase_dom-like.
PfamiView protein in Pfam
PF00293. NUDIX. 1 hit.
PRINTSiPR00502. NUDIXFAMILY.
SUPFAMiSSF55811. SSF55811. 1 hit.
PROSITEiView protein in PROSITE
PS51462. NUDIX. 1 hit.
PS00893. NUDIX_BOX. 1 hit.

Sequencei

Sequence statusi: Complete.

O66548-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKKEFSAGGV LFKDGEVLLI KTPSNVWSFP KGNIEPGEKP EETAVREVWE
60 70 80 90 100
ETGVKGEILD YIGEIHYWYT LKGERIFKTV KYYLMKYKEG EPRPSWEVKD
110 120 130
AKFFPIKEAK KLLKYKGDKE IFEKALKLKE KFKL
Length:134
Mass (Da):15,756
Last modified:August 1, 1998 - v1
Checksum:iDA363A35A82628DF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000657 Genomic DNA. Translation: AAC06510.1.
PIRiA70315.
RefSeqiNP_213108.1. NC_000918.1.
WP_010880046.1. NC_000918.1.

Genome annotation databases

EnsemblBacteriaiAAC06510; AAC06510; aq_158.
GeneIDi1192691.
KEGGiaae:aq_158.

Similar proteinsi

Entry informationi

Entry nameiO66548_AQUAE
AccessioniPrimary (citable) accession number: O66548
Entry historyiIntegrated into UniProtKB/TrEMBL: August 1, 1998
Last sequence update: August 1, 1998
Last modified: August 30, 2017
This is version 120 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported