Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

AP4A hydrolase

Gene

apfA

Organism
Aquifex aeolicus (strain VF5)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei6ATPCombined sources1
Binding sitei31ATPCombined sources1
Binding sitei67ATPCombined sources1
Binding sitei78ATPCombined sources1
Binding sitei115ATPCombined sources1

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

HydrolaseUniRule annotationSAAS annotationImported

Keywords - Ligandi

ATP-bindingCombined sources, Nucleotide-binding

Enzyme and pathway databases

BRENDAi3.6.1.17. 396.

Names & Taxonomyi

Protein namesi
Submitted name:
AP4A hydrolaseImported
Gene namesi
Name:apfAImported
Ordered Locus Names:aq_158Imported
OrganismiAquifex aeolicus (strain VF5)Imported
Taxonomic identifieri224324 [NCBI]
Taxonomic lineageiBacteriaAquificaeAquificalesAquificaceaeAquifex
Proteomesi
  • UP000000798 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi224324.aq_158.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3I7UX-ray1.80A/B/C/D1-134[»]
3I7VX-ray1.95A/B1-134[»]
ProteinModelPortaliO66548.
SMRiO66548.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiO66548.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini2 – 127Nudix hydrolaseInterPro annotationAdd BLAST126

Sequence similaritiesi

Belongs to the Nudix hydrolase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108WNV. Bacteria.
COG0494. LUCA.
HOGENOMiHOG000261976.
InParanoidiO66548.
KOiK03574.
OMAiYEGWVLP.
OrthoDBiPOG091H049J.

Family and domain databases

Gene3Di3.90.79.10. 1 hit.
InterProiIPR020476. Nudix_hydrolase.
IPR020084. NUDIX_hydrolase_CS.
IPR000086. NUDIX_hydrolase_dom.
IPR015797. NUDIX_hydrolase_dom-like.
[Graphical view]
PfamiPF00293. NUDIX. 1 hit.
[Graphical view]
PRINTSiPR00502. NUDIXFAMILY.
SUPFAMiSSF55811. SSF55811. 1 hit.
PROSITEiPS51462. NUDIX. 1 hit.
PS00893. NUDIX_BOX. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

O66548-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKKEFSAGGV LFKDGEVLLI KTPSNVWSFP KGNIEPGEKP EETAVREVWE
60 70 80 90 100
ETGVKGEILD YIGEIHYWYT LKGERIFKTV KYYLMKYKEG EPRPSWEVKD
110 120 130
AKFFPIKEAK KLLKYKGDKE IFEKALKLKE KFKL
Length:134
Mass (Da):15,756
Last modified:August 1, 1998 - v1
Checksum:iDA363A35A82628DF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000657 Genomic DNA. Translation: AAC06510.1.
PIRiA70315.
RefSeqiNP_213108.1. NC_000918.1.
WP_010880046.1. NC_000918.1.

Genome annotation databases

EnsemblBacteriaiAAC06510; AAC06510; aq_158.
GeneIDi1192691.
KEGGiaae:aq_158.
PATRICi20957992. VBIAquAeo85532_0136.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000657 Genomic DNA. Translation: AAC06510.1.
PIRiA70315.
RefSeqiNP_213108.1. NC_000918.1.
WP_010880046.1. NC_000918.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3I7UX-ray1.80A/B/C/D1-134[»]
3I7VX-ray1.95A/B1-134[»]
ProteinModelPortaliO66548.
SMRiO66548.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi224324.aq_158.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC06510; AAC06510; aq_158.
GeneIDi1192691.
KEGGiaae:aq_158.
PATRICi20957992. VBIAquAeo85532_0136.

Phylogenomic databases

eggNOGiENOG4108WNV. Bacteria.
COG0494. LUCA.
HOGENOMiHOG000261976.
InParanoidiO66548.
KOiK03574.
OMAiYEGWVLP.
OrthoDBiPOG091H049J.

Enzyme and pathway databases

BRENDAi3.6.1.17. 396.

Miscellaneous databases

EvolutionaryTraceiO66548.

Family and domain databases

Gene3Di3.90.79.10. 1 hit.
InterProiIPR020476. Nudix_hydrolase.
IPR020084. NUDIX_hydrolase_CS.
IPR000086. NUDIX_hydrolase_dom.
IPR015797. NUDIX_hydrolase_dom-like.
[Graphical view]
PfamiPF00293. NUDIX. 1 hit.
[Graphical view]
PRINTSiPR00502. NUDIXFAMILY.
SUPFAMiSSF55811. SSF55811. 1 hit.
PROSITEiPS51462. NUDIX. 1 hit.
PS00893. NUDIX_BOX. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiO66548_AQUAE
AccessioniPrimary (citable) accession number: O66548
Entry historyi
Integrated into UniProtKB/TrEMBL: August 1, 1998
Last sequence update: August 1, 1998
Last modified: November 30, 2016
This is version 116 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.