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Protein
Submitted name:

Transcriptional regulator (H-T-H)

Gene

hth

Organism
Aquifex aeolicus (strain VF5)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi2 – 11ATPPROSITE-ProRule annotation10

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processTranscription, Transcription regulationPROSITE-ProRule annotationSAAS annotation
LigandATP-bindingPROSITE-ProRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Transcriptional regulator (H-T-H)Imported
Gene namesi
Name:hthImported
Ordered Locus Names:aq_093Imported
OrganismiAquifex aeolicus (strain VF5)Imported
Taxonomic identifieri224324 [NCBI]
Taxonomic lineageiBacteriaAquificaeAquificalesAquificaceaeAquifex
Proteomesi
  • UP000000798 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi224324.aq_091m.

Structurei

3D structure databases

ProteinModelPortaliO66502.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 140Sigma-54 factor interactionInterPro annotationAdd BLAST140

Phylogenomic databases

eggNOGiENOG4108JUB. Bacteria.
COG3829. LUCA.
InParanoidiO66502.
OMAiRALEMSH.
OrthoDBiPOG091H03UM.

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
3.40.50.300. 1 hit.
InterProiView protein in InterPro
IPR009057. Homeobox-like.
IPR002197. HTH_Fis.
IPR027417. P-loop_NTPase.
IPR002078. Sigma_54_int.
IPR025944. Sigma_54_int_dom_CS.
PfamiView protein in Pfam
PF02954. HTH_8. 1 hit.
PF00158. Sigma54_activat. 1 hit.
PRINTSiPR01590. HTHFIS.
SUPFAMiSSF46689. SSF46689. 1 hit.
SSF52540. SSF52540. 1 hit.
PROSITEiView protein in PROSITE
PS00688. SIGMA54_INTERACT_3. 1 hit.
PS50045. SIGMA54_INTERACT_4. 1 hit.

Sequencei

Sequence statusi: Complete.

O66502-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MANGGTLFLD EIGELPLHLQ VKLLGLIQDK EFERIGDLKP RKADVRIIAA
60 70 80 90 100
TNKNLKKLVE EGKFREDLYY RLNVVNVELP PLRERKEDIP HLVSYFLEKF
110 120 130 140 150
SKIHGKKVKG VSPEAMKLLL EYDYPGNVRE LENAIEHAVV VSSTSLIGPD
160 170 180 190 200
DLPEEIRIGS KVKKKFRENE ELEKIKEALE RAGGNKSLAA KLLGIHRTTL
210
WRKLKEYGLA
Length:210
Mass (Da):23,948
Last modified:August 1, 1998 - v1
Checksum:i29E0F23B11FD1A77
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000657 Genomic DNA. Translation: AAC06459.1.
PIRiC70309.
RefSeqiNP_213061.1. NC_000918.1.

Genome annotation databases

EnsemblBacteriaiAAC06459; AAC06459; aq_093.
GeneIDi1193997.
KEGGiaae:aq_091m.
PATRICi20957882. VBIAquAeo85532_0081.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000657 Genomic DNA. Translation: AAC06459.1.
PIRiC70309.
RefSeqiNP_213061.1. NC_000918.1.

3D structure databases

ProteinModelPortaliO66502.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi224324.aq_091m.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC06459; AAC06459; aq_093.
GeneIDi1193997.
KEGGiaae:aq_091m.
PATRICi20957882. VBIAquAeo85532_0081.

Phylogenomic databases

eggNOGiENOG4108JUB. Bacteria.
COG3829. LUCA.
InParanoidiO66502.
OMAiRALEMSH.
OrthoDBiPOG091H03UM.

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
3.40.50.300. 1 hit.
InterProiView protein in InterPro
IPR009057. Homeobox-like.
IPR002197. HTH_Fis.
IPR027417. P-loop_NTPase.
IPR002078. Sigma_54_int.
IPR025944. Sigma_54_int_dom_CS.
PfamiView protein in Pfam
PF02954. HTH_8. 1 hit.
PF00158. Sigma54_activat. 1 hit.
PRINTSiPR01590. HTHFIS.
SUPFAMiSSF46689. SSF46689. 1 hit.
SSF52540. SSF52540. 1 hit.
PROSITEiView protein in PROSITE
PS00688. SIGMA54_INTERACT_3. 1 hit.
PS50045. SIGMA54_INTERACT_4. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiO66502_AQUAE
AccessioniPrimary (citable) accession number: O66502
Entry historyiIntegrated into UniProtKB/TrEMBL: August 1, 1998
Last sequence update: August 1, 1998
Last modified: February 15, 2017
This is version 114 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.